Mass Spectrometers
Bruker timsTOF AIP
Coming soon!
Bruker timsTOF HT
The timsTOF HT is Bruker's latest iteration of the high dynamic range trapped ion mobility spectrometry (tims) time-of-flight (TOF) mass spectrometer, with the high capacity TIMS-XR analyzer and advanced digitizer technology. The timsTOF HT supports parallel accumulation serial fragmentation (PASEF), allowing for rapid and efficient data acquisition with high dynamic range and increased coverage of the proteome for label-free quantification.
Thermo Orbitrap Fusion
The Thermo Scientific Orbitrap Fusion Tribrid™ mass spectrometer is equipped with three mass analyzers that permit complex MSn experimental design: a quadrupole, an Orbitrap and a linear ion trap. CID, HCD, and ETD fragmentation modes, scan speeds up to 20 Hz, resolution up to 500,000 (FWHM) at m/z 200 in the Orbitrap.
Thermo Orbitrap Fusion Lumos
The Thermo Scientific Orbitrap Fusion Lumos Tribrid™ Mass Spectrometer provides key improvements to Fusion that enhance analytical performance, including a brighter ion source, a segmented quadrupole with higher selectivity, and Advanced Vacuum Technology for improved transmission.
Thermo Q Exactive Plus
The Thermo Scientific Q Exactive™ Plus benchtop LC-MS offers high performance quadrupole precursor selection followed by high-resolution, accurate-mass (HR/AM) full scan Orbitrap detection. Sub-ppm mass accuracy, scan speeds up to 12 Hz, mass resolution up to 140,000 (FWHM) at m/z 200.
HPLCs
Bruker proteoElute
The proteoElute is a nanoflow liquid chromatography system designed for robust and ultra-sensitive applications and is paired with our timsTOF HT and timsUltra AIP mass spectrometers for on-line peptide and protein separations.
Thermo Easy-nLC 1000
The Thermo Scientific Easy nLC™ 1000 is a nano-flow UHPLC with a pressure rating of 1000 bar and is used for on-line separation with the Q Exactive™ Plus.
Thermo Easy-nLC 1200
The Thermo Scientific Easy nLC™ 1200 is a nano-flow UHPLC with a pressure rating of 1200 bar and is used for on-line separation with the Orbitrap Fusion Tribrid™.
Thermo Vanquish Neo
The Thermo Scientific Vanquish Neo UHPLC system delivers reproducible nano-flow LC-MS with a pressure rating of 1500 bar. The Vanquish is used for on-line separation with the Orbitrap Fusion Lumos Tribrid™.
Waters ACQUITY Arc
The Waters ACQUITY Arc is used for uHPLC pre-fractionation of complex peptide mixtures. Common applications include off-line fractionation of TMT-labeled peptides from whole proteome or phosphoproteome preparations and fractionation of unlabeled peptides for spectral library generation.