Landino Laboratory

About Us

How do cells organize themselves to divide?

We reconstruct the cell cortex from its molecular components to discover how biochemical signaling, membranes, and the cytoskeleton self-organize into the dynamic patterns that drive cytokinesis.

We build cells to understand them.

Cyotosol + membrane 
            ↓
Artificial cell cortex
            ↓
Self-organized patterns
            ↓
Cytokinesis

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Recent Publications

Membrane composition-dependent patterning of Rho and F-actin in an artificial cell cortex.
Schwarz GJ, Suber JR, Andhare D, Ragusa MJ, Landino J
Mol Biol Cell. 2026 Apr 1;37(4):ar30. doi: 10.1091/mbc.E25-07-0362. Epub 2026 Feb 18.
PMID: 41705942

Neighbor cells restrain furrowing during Xenopus epithelial cytokinesis.
Landino J, Misterovich E, van den Goor L, Adhikary B, Chumki S, Davidson LA, Miller AL
Dev Cell. 2025 Aug 18;60(16):2139-2148.e6. doi: 10.1016/j.devcel.2025.03.010. Epub 2025 Apr 8.
PMID: 40203834

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