Student Publications and Awards

Arielle Baker

Awards
Top Speaker Award, University of Vermont Neuroscience, Behavior & Health Research Forum, 2016
American Association for the Advancement of Science (AAAS) Program for Excellence in Science, 2015


Stephanie Bouley

Publications
Allaway RJ, Fischer DA, de Abreu FB, Gardner TB, Gordon SR, Barth RJ, Colacchio TA, Wood M, Kacsoh BZ, Bouley SJ, Cui J, Hamilton J, Choi JA, Lange JT, Peterson JD, Padmanabhan V, Tomlinson CR, Tsongalis GJ, Suriawinata AA, Greene CS, Sanchez Y, Smith KD. Fine-needle biopsy patient-derived xenografts from early stage pancreatic cancer and patient-matched metastatic-PDX models for testing targeted agents. Oncotarget. 2016 Feb 25.

Allaway RJ, Wood MD, Downey SL, Bouley SJ, Traphagan NA, Wells JD, Batra J, Melancon SN, Ringelberg C, Seibel W, Ratner N, and Sanchez Y. Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells. July 18. Oncotarget. 2017

Hosford SR, Dillon LM, Bouley SJ, Rosati R, Yang W, Chen VS, Demidenko E, Morra RP, Miller TW. Combined inhibition of both p110α and p110β isoforms of phosphatidylinositol 3-kinase is required for sustained therapeutic effect in PTEN-deficient, ER+ breast cancer. Clin Cancer Res. 2016 Nov 30.

Way GP, Allaway RJ, Bouley SJ, Fadul CE, Sanchez Y, and Greene CS. A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma. BMC Genomics. 2017 Feb 6.

Awards
Best Poster Award, Molecular Therapeutics of Cancer Research Conference, Burlington VT, 2017
Children's Tumor Foundation Young Investigator Award 2016
Dartmouth Graduate Student Travel Award, 2017


Heidi Chapman

Publications
Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA. PTEN recruitment controls synaptic and cognitive function in Alzheimer's models. Nat Neurosci. 2016;19:443-53.


David Chen

Publications
Chen Y*, Marotti JD*, Jensen EG, Onega TL, Johnson KC, Christensen BC. “Concordance of DNA methylation profiles between breast core biopsy and surgical excision specimens containing ductal carcinoma in situ (DCIS)”. Exp. Mol. Path. 2017; 103: 78-83.

Awards
Burroughs-Wellcome Big Data in Life Sciences (BDLS) Fellowship


Will Feng

Publications
Matsuura K, Canfield K, Feng W, Kurokawa M. Metabolic Regulation of Apoptosis in Cancer. Int Rev Cell Mol Biol. 2016;327:43-87.


Edmond Feris

Publications
Bates D, Feris EJ, Danilov AV, Eastman A. Rapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105. Cancer Biol Ther. 2016.

Feris EJ, Encinales L, Awad C, Stern JN, Tabansky I, Jiménez-Alvarez L, Ramírez-Martínez G, Cruz-Lagunas A, Bobadilla K, Márquez E, Granados-Montiel J, Rodriguez-Reyna TS, Fernandez-Vina M, Granados J, Zuñiga J, Yunis EJ. High levels of anti-tuberculin (IgG) antibodies correlate with the blocking of T-cell proliferation in individuals with high exposure to Mycobacterium tuberculosis. Int J Infect Dis. 2016;43:21.

Awards
Albert J. Ryan Predoctoral Fellowship, 2016


Sarah Hosford

Publications
Hosford SR, Dillon LM, Bouley SJ, Rosati R, Yang W, Chen VS, Demidenko E, Morra RP, Miller TW. Combined inhibition of both p110α and p110β isoforms of phosphatidylinositol 3-kinase is required for sustained therapeutic effect in PTEN-deficient, ER+ breast cancer. Clin Cancer Res. 2016 Nov 30.

Yang W, Hosford SR, Dillon LM, Shee K, Liu SC, Bean JR, Salphati L, Pang J, Zhang X, Nannini MA, Demidenko E, Bates DJ, Lewis LD, Marotti JD, Eastman A, Miller TW. Strategically timing inhibition of phosphatidylinositol 3-kinase to maximize therapeutic index in estrogen receptor alpha-positive, PIK3CA-mutant breast cancer. Clin Cancer Res. 2016.

Bean JR, Hosford SR, Symonds LK, Owens P, Dillon LM, Yang W, Shee K, Schwartz GN, Marotti JD, Muller KE, Rosenkranz KM, Barth RJ, Chen VS, Agarwal VR, Miller TW. The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer. Breast Cancer Res Treat. 2015;149:69-79.

Hosford SR, Miller TW. Clinical potential of novel therapeutic targets in breast cancer: CDK4/6, Src, JAK/STAT, PARP, HDAC, and PI3K/AKT/mTOR pathways. Pharmgenomics Pers Med. 2014;7:203-15.


Leslie Lupien

Publications
Kinlaw WB, Baures PW, Lupien LE, Davis WL, Kuemmerle NB. Fatty Acids and Breast Cancer: Make them on Site or have them Delivered. J Cell Physiol. 2016.

Zaidi N, Lupien L, Kuemmerle NB, Kinlaw WB, Swinnen JV, Smans K. Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids. Prog Lipid Res. 2013; 52(4):585-9.


David Mallick

Awards
Best Poster Award, Molecular Therapeutics of Cancer Research
Conference, Burlington VT, 2017


Kyla Rodgers

Publications
Rodgers KR, Gui J, Dinulos MB, Chou RC. Ehlers-Danlos syndrome hypermobility type is associated with rheumatic diseases. Sci Rep. 2017 Jan 4;7:39636.

Langan TJ, Rodgers KR, Chou RC. Synchronization of Mammalian Cell Cultures by Serum Deprivation. Methods Mol Biol. 2017;1524:97-105.

Li V, Langan TJ, Rodgers KR, Chou RC. Differential and kinetic effects of cell cycle inhibitors on neoplastic and primary astrocytes. Cell Cycle. 2016 Oct;15:2669-2679.

Rodgers KR, Chou RC. Therapeutic monoclonal antibodies and derivatives: Historical perspectives and future directions. Biotechnol Adv. 2016 Nov 1;34:1149-58.


Kevin Shee

Publications
Yang W, Hosford SR, Dillon LM, Shee K, Liu SC, Bean JR, Salphati L, Pang J, Zhang X, Nannini MA, Demidenko E, Bates DJ, Lewis LD, Marotti JD, Eastman A, Miller TW. Strategically timing inhibition of phosphatidylinositol 3-kinase to maximize therapeutic index in estrogen receptor alpha-positive, PIK3CA-mutant breast cancer. Clin Cancer Res. 2016.

Gogna R, Shee K, Moreno E. Cell Competition During Growth and Regeneration. Annu Rev Genet. 2015;49:697-718.

Bean JR, Hosford SR, Symonds LK, Owens P, Dillon LM, Yang W, Shee K, Schwartz GN, Marotti JD, Muller KE, Rosenkranz KM, Barth RJ, Chen VS, Agarwal VR, Miller TW. The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer. Breast Cancer Res Treat. 2015;149:69-79.


Patrick Skelton

Publications
Robinson S, Todd TP, Pasternak AR, Luikart BW, Skelton PD, Urban DJ, Bucci DJ. Chemogenetic silencing of neurons in retrosplenial cortex disrupts sensory preconditioning. J Neurosci. 2014 13;34:10982-8.


Emily Stephens

Publications
Gulledge AT, Dasari S, Onoue K, Stephens EK, Hasse JM, Avesar D. A sodium-pump-mediated afterhyperpolarization in pyramidal neurons. J Neurosci. 2013;33:13025-41.

Stephens EK, Avesar D, Gulledge AT. Activity-dependent serotonergic excitation of callossal projection neurons in the mouse prefrontal cortex. Front Neural Circuits. 2014. Aug 26;8:97. doi: 10.3389/fncir.2014.00097. eCollection 2014.

Awards
National Institutes of Drug Abuse (NIDA) Travel Award 2016 for the International Society for Serotonin Research
The Graduate Alumni Research Award, 2015
Neuroscience Center at Dartmouth Travel Award, 2013 & 2014


Nicholas Warren

Awards
Albert J. Ryan Predoctoral Fellowship, 2016


Owen Wilkins

Publications
Canfield K, Li J, Wilkins OM, Morrison MM, Ung M, Wells W, Williams CR, Liby KT, Vullhorst D, Buonanno A, Hu H, Schiff R, Cook RS, Kurokawa M. Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells. Cell Cycle. 2015;14:648-55.

Wilkins OM, Downey SL, Weyburne ES, Williams DA, Mirabella AC, Overkleeft HS, Kisselev AF. Cell-line-specific high background in the Proteasome-Glo assay of proteasome trypsin-like activity. Anal Biochem. 2014; 451:1-3.

Wilkins OM, Titus AJ, Gui J, Eliot M, Butler RA, Sturgis EM, Li G, Kelsey KT, Christensen BC. Genome-scale identification of microRNA-related SNPs associated with risk of head and neck squamous cell carcinoma. Carcinogenesis. 2017; 10.1093/carcin/bgx056.

Weyburne ES, Wilkins OM, Sha Z, Williams DA, Pletnev AA, de Bruin G, Overkleeft HS, Goldberg AL, Cole MD, Kisselev AF. Inhibition of the Proteasome β2 Site Sensitizes Triple-Negative Breast Cancer Cells to β5 Inhibitors and Suppresses Nrf1 Activation. Cell Chem Biol. 2017; 24:218-230.

Awards
Neukom Institute Travel Grant, 2016
Best Journal Club Presentation, MPTT/CBMT seminar series, 2014
Best Journal Club Presentation, MPTT/CBMT seminar series, 2015
Neukom Institute Travel Grant, 2017
National Institute of General Medical Sciences Workshop Scholarship , 2017