Marina Kirkland, a MCB graduate student, recently joined the laboratory. Her project aims to elucidate the role of cytotoxic cells following infection with certain Aspergillus fumigatus strains.
Our collaborative paper examining the role of leukotriene B4 in regulating the inflammatory response induced by Aspergillus fumigatus was recently published in a special research topic in Frontiers in Immunology entitled: “Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference”. The work was spearheaded by Alayna Caffrey-Carr and involved a collaboration with Dr. Robert Cramer’s laboratory.
Our collaborative paper examining Aspergillus fumigatus strain specific inflammatory responses was recently published in Infection & Immunity and selected by the editor as an “Article of Significant Interest from This Issue”. The work was spearheaded by Alayna Caffrey-Carr and involved collaborations with both Dr. Robert Cramer’s and Dr. Tobias Hohl’s laboratories.
A collaboration with Dr. Amariliz Rivera and colleagues examining the role of type I and type III interferon in host resistance against Aspergillus fumigatus was recently published in Science Immunology.
Dylan Wang, a MCB graduate student, recently joined the laboratory. His project aims to further elucidate why certain Aspergillus fumigatus strains induce distinct inflammatory responses.
Alayna Caffrey-Carr successfully defend her Ph.D. thesis entitled: "THE ROLES OF INTERLEUKIN-1 AND LEUKOTRIENE-B4 IN THE INNATE IMMUNE RESPONSE TO PULMONARY ASPERGILLUS FUMIGATUS INFECTION". Alayna will be moving on to become a post-doctoral fellow in the laboratory of Dr. Ross Kedl at the University of Colorado – Denver. CONGRATULATIONS!
Drs. Josh Obar and Rachel Temple recently attended the Immunology 2017™ Meeting held in Washington DC. Both presented their work at the meeting and participated in AAI’s Capitol Hill Day.
McKenzie Stannard recently joined the laboratory as a Research Technician. His project aims to elucidate why certain Aspergillus fumigatus strains grow better in the mammalian respiratory tract than others.
Dr. Josh Obar, Alayna Caffrey, and Rachel Temple recently attended the Immunology 2016™ Meeting held in Seattle, Washington. Both Alayna and Rachel were awarded AAI Trainee Abstract Awards to present their research. Rachel gave a short talk entitled "When signals get crossed: the consequences of dual allergen- and influenza-mediated signaling in mast cells" in the Mast Cell & IgE Block Symposium, while Alayna gave a short talk entitled "Aspergillus fumigatus strain-specific host response is regulated by glucose sensing" in the Molecular Signatures of Eukaryotic Pathogens Block Symposium. CONGRATULATIONS!
Rachel Temple was one of ten young investigators selected to participate in the sixth class of the AAI Public Policy Fellowship Program. CONGRATULATIONS!
Dr. Josh Obar and Alayna Caffrey recently attended the 7th Advance Against Aspergillosis Meeting held in Manchester, UK. Dr. Obar gave a short talk entitled "Compartment-specific activation of the inflammasome by Aspergillus fumigatus" and Alayna presented a poster on Aspergillus fumigatus strain specific immune response. Based on Alayna's poster presentation she was selected as one of the Outstanding Poster Presenters at the meeting. CONGRATULATIONS!
Rachel Temple recently attended the both the Gordon Research Seminar and Gordon Research Conference on the Biology of Acute Respiratory Infections held in Galveston, Texas. Based on her submitted abstract she was invited to give short talks at BOTH meetings. CONGRATULATIONS!
Alayna Caffrey was recently awarded the Ferguson Award from the Department of Microbiology & Immunology at Montana State University. This award is given to a Ph.D. candidate in recognition of excellence in research. CONGRATULATIONS!
Rachel Temple was recently awarded the Translational Immunology Travel Award from ImmuNext. Rachel will attend the Gordon Research Conference on the Biology of Acute Respiratory Infections to be held in Galveston, Texas in February 2016. CONGRATULATIONS!
The Obar Laboratory officially moves back to Dr. Obar's alma mater, the Department of Microbiology & Immunology at the Geisel School of Medicine
Dr. Josh Obar was recently appointed an Associate Editor at the Journal of Immunology.
Alayna Caffrey was recently awarded the Kopriva Graduate Fellowship from the College of Letters & Sciences at Montana State University. CONGRATULATIONS!
Dr. Josh Obar gave an invited seminar in the Society for Leukocyte Biology Symposium at the 2015 American Association of Immunologist Annual Meeting in New, Orleans, LA.
Our review on the role that mast cell plays in virus induced immunopathology was recently published in Frontiers in Immunology as part of the Research Topic on "Influenza Virus Vaccines and Immunotherapies".
CONGRATULATIONS to Dr. Amy C. Graham who graduated with her PhD from the Department of Microbiology & Immunology, we will miss you! Good luck at OUHSC with Dr. Noah Butler.
Dr. Josh Obar and Alayna Caffrey recently attended the Gordon Research Conference on Fungal Immunology in Galveston, TX. Alayna gave a talk on her IL-1α project at the Gordon Research Seminar held prior to the conference and was selected for the Best Oral Presentation at the seminar. CONGRATULATIONS, Alayna!
Our manuscript examining the role of IL-1α in regulating the neutrophil response following Aspergillus fumigatus challenge was recently published in PLoS Pathogens.
The Obar Laboratory welcome Dr. Rachel M. Temple, Ph.D. to the laboratory as a post-doctoral fellow. Dr. Temple received her Ph.D. from Pennsylvania State University Medical Center in Hershey, PA working in the laboratory of Dr. Clare Sample.
Dr. Josh Obar, Alayna Caffrey, and Amy Graham recently attended the annual American Association of Immunology meeting in Pittsburgh, PA. Amy and Dr. Obar both gave a talks on the role of mast cells during influenza A virus infections.
Dr. Josh Obar and Amy Graham recently attended the Keystone Symposium on the Pathogenesis of Respiratory Viruses in Keystone, CO. Amy gave a short talk on role of the influenza hemagglutinin in the activation of mast cells.
Dr. Josh Obar was awarded one of five ICAAC Young Investigator Award by the American Society for Microbiology at the ICAAC Meeting in Denver, CO.
Dr. Josh Obar was award an R01 from NIH/NIAID entitled: "Mast cell dependent inflammation during respiratory influenza A virus infection".
Dr. Josh Obar was one of ten young investigators selected to participate in the second class of the AAI Public Policy Fellowship Program.