Pharmacology (PHARM)

The PHARM LC covers pharmacodynamics, pharmacokinetics, and clinical properties of drugs, as well as preparing students to recognize and address the scientific, social, economic, legal, and ethical factors that affect drug development, availability, and application.

Longitudinal Curriculum Leader (Interim)

David W. Mullins, PhD

Email: David.W.Mullins@Dartmouth.edu
Phone: 603 650-1208 (office) or 802 299-8960 (text)
Office Location: 232 Remsen Hall
Twitter @dmullinsdms
Instagram @dmullinsvt
LinkedIn https://www.linkedin.com/in/dmullinsdms/

Dr. Mullins trained as a research microbiologist and immunologist at Virginia Tech and the University of Virginia.  He has instructed microbiology, immunology, and virology at UVa (2003-2011) and Geisel (2011-present).  Dr. Mullins has published in the field of cancer immunology and immunotherapy and presently serves as Associate Dean for Basic Science Integration at Geisel.

Longitudinal Curriculum Objectives

  1. Describe the pharmacokinetic properties (absorption, distribution, metabolism, and elimination) that apply to all drugs, and how they are affected by anatomy, biochemistry, genetics, and physiology.
  2. Explain how drugs interact with receptors, cells, tissues, and organs to produce pharmacodynamic effects, and describe the categories these drugs are classified under (e.g., agonism, antagonism, inhibition) based on the nature of their drug-receptor interactions.
  3. Describe and differentiate the pharmacodynamic, pharmacokinetic, and clinical properties (therapeutic and adverse) of the commonly prescribed classes of drugs, including specific class-representitive drugs, used to treat the clinical indications associated with each of the major organ systems.
  4. Solve the fundamental pharnacokinetic equations to obtain values that are used in measuring drug serum levels and to calculate patient drug doses, and describe the factors that can affect drug dosages for special patient groups.
  5. Explain how diet and nutrition, including the use of dietary, herbal, and over-the-counter supplements, can affect the efficacy and safety of prescribed drugs.
  6. Discuss the scientific, social, economic, legal and ethical factors that can affect the development, FDA approval and regulation, pricing, advertising, and availability of drugs (branded and generic), and their impact on pharmacotherapy.
  7. Generate a proper and legal prescription, explain what is required to ensure a patient is fully counseled about their medications, and demonstrate the skills necessary for assisting patients to understand treatment options.
  8. Discuss clinical cases in small groups, demonstrate the ability to communicate clearly and behave professionally with other students and faculty, and participate effectively as a team member.