The Pathology and Laboratory Medicine (PATH) Longitudinal Curriculum will provide students with the opportunity to learn the fundamental, pathophysiologic changes that occur in cellular injury, inflammation, healing, autoimmunity and neoplasia; and then to apply these concepts to individual organs and organ systems in support of the understanding of human disease. Over the course of the four-year curriculum, students will be expected to build an appreciation of the role of Pathology and Laboratory Medicine in disease diagnosis, monitoring, treatment, outcomes, and public health.
Longitudinal Curriculum Leader
Candice C. Black, DO
Office Location: DHMC, Borwell 4th floor
1992, University of Mississippi, Oxford MS – BA, Chemistry
1996, Nova Southeastern University, College of Osteopathic Medicine, Davie, FL – DO
1996-1997, Intern, Florida Medical Center, Plantation, FL
1997-2000 , Resident in Anatomic/Clinical Pathology, Mount Sinai Medical Center, New York, NY
2000-2001, Chief Resident, Anatomic/ Clinical Pathology, Mount Sinai Medical Center, New York, NY
2000 (Jan), Fellow, Department of Pulmonary and Mediastinal Pathology, Armed Forces Institute of Pathology, Washington D.C.
2001-2002 , Fellow, Oncologic Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY
Dartmouth Hitchcock Medical Center, Pathology and Laboratory Medicine, since 2002.
Dr. Black focuses on diagnostic surgical pathology of the head, neck, lung and breast. Other interests include medical education, pathology-specific teaching and feedback, curriculum design, and evaluation.
Longitudinal Curriculum Objectives
- Describe the medical subspecialty field of Pathology and Laboratory Medicine, its distinct terminology, and its relationship to other medical disciplines and regulatory bodies.
- Explain cellular injury, adaptation and healing with resultant changes in the tissues and organs
- Describe the pathways and mechanisms of injury produced by radiation, chemical injury, environmental toxins, physical stressors, and nutrient deficiency and excess across tissues and organs.
- Explain the pathophysiologic mechanisms of acute and chronic inflammation, the associated mediators, and the functional effects at the cellular, tissue and organ levels across different systems.
- Explain how mechanisms of immune system dysfunction produce cellular injury, acute and chronic inflammation, autoimmunity, allergic reactions, and susceptibility to infection; how these changes affect function; and how therapeutic intervention can mitigate these effects.
- Predict the pathogenic mechanisms, and clinical manifestations, of infectious diseases at the cellular, tissue and organism levels.
- Using knowledge of the pathogenic mechanisms that result in shock, heart failure, atherosclerosis and alterations in hemostasis, explain the clinical manifestations associated with these pathologic changes.
- Using knowledge of the functional consequences of changes in the genome, explain the molecular genetic mechanisms in developmental and functional abnormalities, and in neoplasia.
- Explain the morphology, biological behavior, nomenclature, classification, grading and staging of neoplasia.
- Identify the pathologic features of organ-specific cancers and describe their clinical presentations (including paraneoplastic syndromes) and diagnostic laboratory markers.
- Describe the pathology, pathophysiology, clinical presentation, diagnosis and treatment monitoring of common, organ-specific diseases. Discuss how pathologists participate in Team care.
- Explain the consultative expertise that is provided by clinical faculty in the disciplines of Pathology and Laboratory Medicine and know when to ask for assistance in clinical test choice, cost or interpretation.
- Using knowledge of the principles of clinical laboratory testing, explain reference ranges and sources of error in medicine.
- Explain the importance of autopsies (hospital and medicolegal), the processes of obtaining and conducting them, and the role of the medical examiner in medicine and jurisprudence.
- Demonstrate the ability to formulate differential and final clinical diagnoses by incorporating presenting signs and symptoms, laboratory data, tissue slide microscopic examination and group discussion.
- Identify and fill gaps in knowledge and understanding while preparing for course sessions.