Clinical Microbiology and Immunology (CMI)

The Clinical Microbiology and Immunology (CMI) Longitudinal Curriculum provides ongoing learning and reinforcement of the principles of microbiology/infectious disease and the host immune response, which are introduced in Phase I during the Infection and Immunity (I3) course.

Across the four-year curriculum, students will develop advanced medically-relevant knowledge of the microorganisms that mediate human health and disease; the pathologic consequences of infectious disease; the mechanisms and functions of the immune system to eliminate pathogens and maintain homeostasis; and the pharmacologic and immunologic interventions to treat infectious and immunologic diseases.

Longitudinal Curricula Co-Leaders

David W. Mullins, PhD

Phone: 603 650-1208 (office) or 802 299-8960 (text)
Office Location: 232 Remsen Hall
Twitter @dmullinsdms
Instagram @dmullinsvt

Dr. Mullins trained as a research microbiologist and immunologist at Virginia Tech and the University of Virginia.  He has instructed microbiology, immunology, and virology at UVa (2003-2011) and Geisel (2011-present).  Dr. Mullins has published in the field of cancer immunology and immunotherapy and presently serves as Associate Dean for Basic Science Integration at Geisel.

Richard A. Zuckerman, MD, MPH

Phone: 603 650-5345 (office) or 802 280-5507 (text)
Office Location: 330W Borwell
Twitter @DartmouthID

Dr. Zuckerman came to Dartmouth in 2005 after completing his residency in Internal Medicine and Fellowship in ID at UW in Seattle, WA.  He is Director of the Infectious Disease Service for Transplant and Immunocompromised Hosts, the Program Director of for the ID Fellowship and is a co-course Director at Geisel for preclinical Infectious Disease content.  He is active clinically in ID and HIV medicine and is co-chair of the GME subcommittee for Diversity, Equity, Inclusion and Belonging at DHMC.  His research has focused on HIV prevention and intervention, Herpes and translational research in immunocompromised hosts.

Longitudinal Curriculum Objectives

  1. Describe the medical subspecialties of Infectious Disease and Allergy/Immunology, and explain their relationship to other medical disciplines.
  2. Recognize and explain the role of the microbiome (the normal flora) in maintaining homeostasis and health.
  3. Describe the morphology, pathogenicity, and immunogenicity of the most important microbial (bacterial, viral, prion, fungal, and parasitic) pathogens in humans.
  4. Recognize the clinical manifestations, symptoms, and pathology induced by the most important microbial pathogens in humans.
  5. Explain the principles of innate and adaptive immunity.
  6. Describe the function of immune effectors in the maintenance of homeostasis and the control of infectious and neoplastic diseases.
  7. Describe the principles of passive and active immunization in the prevention and control of infectious and neoplastic diseases.
  8. Explain and interpret microbiologic, immunologic, and pathology diagnostic methodologies, and correlate these findings with other laboratory and clinical data to generate a diagnosis for infectious and immunologic diseases.
  9. Describe the mechanisms and application of antimicrobial agents in the treatment of infectious diseases, and practice antibiotic stewardship.
  10. Describe immune system disorders and their treatments.
  11. Explain the rationale and application of immunotherapeutic agents, and describe the potential contraindications, adverse reactions, and drug interactions.
  12. Apply clinical reasoning to formulate therapeutic approaches for infectious and immunologic diseases.
  13. Describe the epidemiology of infections caused by the most important human pathogens.
  14. Explain the medical, social, and economic significance of community- and hospital-acquired infections.
  15. Describe the structure and functions of hospital infection control programs and infection control isolation procedures that are appropriate to specific diseases.
  16. Identify and interpret connections between local and global events relating to infectious and immunologic diseases.
  17. Discuss ethics and confidentiality as related to patients with infectious and immunologic diseases.
  18. Identify the historical, economic, cultural, and societal impacts of critical issues in infectious and immunologic diseases.
  19. Critically read, interpret, and assess current literature in human infectious and immunologic diseases. Effectively communicate with patients and peers about infectious and immunologic diseases and their treatments.