Precisely orchestrated changes in cell proliferation and differentiation drive the remarkable transformation of a single cell to a fully developed embryo. In all metazoans, a small number of evolutionarily conserved proteins instruct this profound process. These proteins, which are the core components of cell-to-cell signaling pathways, allow one cell to communicate with its neighbors and to thereby direct and coordinate their behavior. Remarkably, deregulation of the same proteins triggers many human diseases, uncovering opportunities for the development of targeted therapies. Join us at the Life Sciences Symposium to learn how the study of cell signaling has revolutionized our understanding of animal development and provided strategies for treatment of human diseases.<\/p>\n
Kathryn Anderson, PhD<\/b>
\nProfessor and Chair of Developmental Biology Program, Sloan-Kettering Institute<\/i><\/p>\n
Yashi Ahmed, MD, PhD<\/b>
\nAssociate Professor of Genetics, Geisel School of Medicine at Dartmouth College<\/p>\n
Jayaraj Rajagopal, MD<\/b>
\nCenter for Regenerative Medicine, Massachusetts General Hospital<\/i><\/p>\n
Jean-Paul Vincent, PhD<\/b>
\nGroup Leader, The Francis Crick Institute<\/i><\/p>\n
Denise Montell, PhD<\/b>
\nDuggan Professor of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara<\/i><\/p>\n
Michael Cole, PhD<\/b>
\nProfessor of Pharmacology and Toxicology, and of Genetics, Geisel School of Medicine at Dartmouth College<\/i><\/p>\n
James Bradner, MD<\/b>
\nAssociate Professor, Dana-Farber Cancer Institute, Harvard Medical School<\/i><\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
Dartmouth Life Sciences Symposium History: 2015 Signal Transduction in Development and Disease Precisely orchestrated changes in cell proliferation and differentiation drive the remarkable transformation of a single cell to a fully developed embryo. In all metazoans, a small number of evolutionarily conserved proteins instruct this profound process. These proteins, which [\u2026] <\/p>\n