{"id":230,"date":"2017-08-31T08:47:18","date_gmt":"2017-08-31T12:47:18","guid":{"rendered":"http:\/\/sites.dartmouth.edu\/koop\/?page_id=230"},"modified":"2026-03-09T20:04:31","modified_gmt":"2026-03-09T20:04:31","slug":"tobacco-research","status":"publish","type":"page","link":"https:\/\/geiselmed.dartmouth.edu\/koop\/research\/tobacco-research\/","title":{"rendered":"Tobacco Research"},"content":{"rendered":"
\"\"<\/a>
Illustration by John Cuneo<\/figcaption><\/figure>\n

The Institute provides a home at Dartmouth for researchers who focus on behavior and non-communicable diseases. We conduct research that has a measurable impact on the risk of these diseases.<\/em><\/p>\n

Tobacco is by far the deadliest commodity. \u00a0The 6 trillion cigarettes produced and consumed each year contribute to millions of deaths worldwide. \u00a0The tobacco industry pioneered public relations campaigns that undermined science showing tobacco causes chronic disease; they manipulate governments to avoid regulation of\u00a0cigarettes in violation of international convention.\u00a0 C. Everett Koop envisioned a world free of tobacco, and the Koop Institute pursues research and policies that will promote the end of cigarette smoking.\u00a0 This includes studies of cigarette marketing and youth use of cigarettes, as well as studies that promote a better understanding of how alternate nicotine delivery systems like e-cigarettes might affect cigarette smoking and health.<\/p>\n

Koop Institute members are required to disclose all\u00a0conflicts of interests.\u00a0Access\u00a0this information on the\u00a0Conflicts of Interest Page<\/a>.<\/p>\n

Selected publications<\/strong><\/h3>\n

Program Evaluation for a Novel Multicomponent Smoking Cessation Intervention for Smokers With Serious Mental Illness. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nBrunette MF<\/strong>, Bourassa JG, Ferron JC, Aschbrenner KA, Santos MM, Gowarty MA, Pratt SI<\/strong>. Health Promot Pract. 2026 Mar;27(2):315-323. doi: 10.1177\/15248399251348169. Epub 2025 Jun 27. PMID: 40575927<\/p>\n

Clinical Pharmacists, Medications, and Contingency Management for Targeting Smoking in HIV Clinics: A Randomized Clinical Trial. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nEdelman EJ, Deng Y, Dziura J, Nahum-Shani I, Weiss JM, Aoun-Barakat L, Bold KW, Harsono D, Mistler C, Payne E, Aiudi S, Sigel KM, Yager JE, Ledgerwood DM, Bernstein SL<\/strong>. JAMA Netw Open. 2026 Feb 2;9(2):e2560593. doi: 10.1001\/jamanetworkopen.2025.60593. PMID: 41758512 Free PMC article.<\/p>\n

Rural-Urban Patterns in Household Rules Limiting Combustible Tobacco, Noncombustible Tobacco, and E-Cigarette Use. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nSteinberg AW, Ozga JE, Tang Z, Stanton CA<\/strong>, Sargent JD<\/strong>, Paulin LM<\/strong>.\u00a0Ann Am Thorac Soc. 2025 Dec;22(12):1836-1842. doi: 10.1513\/AnnalsATS.202504-419OC. PMID: 40587370<\/p>\n

An Examination of Sex Differences and Cigarette Smoking as Predictors of COPD Prevalence and Incidence in Older US Adults. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nOzga JE, Steinberg AW, Sargent JD<\/strong>, Tang Z, Stanton CA<\/strong>, Paulin LM<\/strong>.\u00a0Nicotine Tob Res. 2025 Aug 5:ntaf162. doi: 10.1093\/ntr\/ntaf162. PMID: 40913563<\/p>\n

Carcinogen reduction in a randomized controlled study comparing e-cigarette provision to assessment only among people with serious mental illness who smoke. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nPratt SI<\/strong>, Ferron JC, Santos M, Brunette MF<\/strong>, Bianco C, Sargent J<\/strong>, Xie H.\u00a0Drug Alcohol Depend. 2025 Sep 1;274:112740. doi: 10.1016\/j.drugalcdep.2025.112740. Epub 2025 Jun 1. PMID: 40505215 Clinical Trial<\/p>\n

An Examination of Sex Differences and Cigarette Smoking as Predictors of COPD Prevalence and Incidence in Older US Adults. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nOzga JE, Steinberg AW, Sargent JD<\/strong>, Tang Z, Stanton CA<\/strong>, Paulin LM<\/strong>.\u00a0Nicotine Tob Res. 2025 Aug 5:ntaf162. doi: 10.1093\/ntr\/ntaf162. PMID: 40913563<\/p>\n

Rural-Urban Patterns in Household Rules Limiting Combustible Tobacco, Noncombustible Tobacco, and E-Cigarette Use. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nSteinberg AW, Ozga JE, Tang Z, Stanton CA, Sargent JD<\/strong>, Paulin LM<\/strong>.\u00a0Ann Am Thorac Soc. 2025 Jun 30. doi: 10.1513\/AnnalsATS.202504-419OC. Online ahead of print. PMID: 40587370<\/p>\n

Program Evaluation for a Novel Multicomponent Smoking Cessation Intervention for Smokers With Serious Mental Illness. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nBrunette MF<\/strong>, Bourassa JG, Ferron JC, Aschbrenner KA, Santos MM, Gowarty MA, Pratt SI. Health Promot Pract. 2025 Jun 27:15248399251348169. doi:\u00a0PMID: 40575927<\/p>\n

Carcinogen reduction in a randomized controlled study comparing e-cigarette provision to assessment only among people with serious mental illness who smoke. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nPratt SI, Ferron JC, Santos M, Brunette MF<\/strong>, Bianco C, Sargent J<\/strong>, Xie H.\u00a0Drug Alcohol Depend. 2025 Jun 1;274:112740. doi: 10.1016\/j.drugalcdep.2025.112740. Online ahead of print. PMID: 40505215<\/p>\n

Corrigendum to \"Correlates of tobacco product initiation among youth and young adults between waves 1-4 of the population assessment of tobacco and Health (PATH) study (2013-2018)\" [Addict. Behav. 134 (2022) 107396]. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nCooper M, Day HR, Ren C, Oniyide O, Corey CG, Ambrose BK, Michael Cummings K, Sargent J<\/strong>, Niaura R, Pierce JP, Kaufman A, Choi K, Goniewicz ML, Stanton CA<\/strong>, Villanti A, Kasza K, Bansal-Travers M, Silveira ML, Kimmel HL, Hull LC, Koblitz A, Poonai K, Paredes A, Taylor K, Borek N, Hyland AJ. Addict Behav. 2025 Mar 26:108343. doi: 10.1016\/j.addbeh.2025.108343. Online ahead of print. PMID: 40148165. No abstract available.<\/p>\n

Functionally important respiratory symptoms and continued cigarette use versus e-cigarette switching: population assessment of tobacco and health study waves 2-6. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nSargent JD<\/strong>, Lauten K, Edwards KC, Tanski SE<\/strong>, MacKenzie TA, Paulin LM<\/strong>, Brunette MF<\/strong>, Goniewicz ML, Malasky A, Stark D, de Moura FB, Griffin H, Nguyen KH, Backlund E, Kimmel HL, Kingsbury JH, Ozga JE, Cummings KM, Hyland A. EClinicalMedicine. 2024 Dec 19;79:102951. doi: 10.1016\/j.eclinm.2024.102951. eCollection 2025 Jan.\u00a0PMID: 39968205 Free PMC article<\/p>\n

Relationship Between Tobacco Product Use and Health-Related Quality of Life Among Individuals With COPD in Waves 1-5 (2013-2019) of the Population Assessment of Tobacco and Health Study. [pubmed.ncbi.nlm.nih.gov]<\/a>
\nPaulin LM<\/strong>., Chronic Obstr Pulm Dis. 2024 Jul 24;11(4):436. doi: 10.15326\/jcopdf.2023.0422E., PMID: 39048097<\/p>\n

Discordance Between Insurance Coverage of Antiviral Medications and Nicotine Replacement Therapy Among Individuals With Human Immunodeficiency Virus Who Smoke<\/a>
\nBernstein SL<\/strong>, Yager JE, Sigel K, Porter E, Do T, Payne E, Bold K, Ledgerwood D, Edelman EJ. J Addict Med. 2024 Apr 12. doi: 10.1097\/ADM.0000000000001302. Online ahead of print. PMID: 38606851<\/p>\n

Tobacco, Alcohol, and Drug Use Among Young Adults with Serious Mental Illness<\/a>
\nFerron JC, Brunette MF<\/strong>, Aschbrenner KA, ElSayed MW, Pratt SI. Community Ment. Health J. 2024 Mar 1. doi: 10.1007\/s10597-024-01246-x. Online ahead of print. PMID: 38427276<\/p>\n

A selective review of smoking cessation interventions in the emergency department<\/span><\/a>
\nPettit N, Pope I, Neuner B, Lash R, Bernstein SL<\/strong>.
\nEmerg Cancer Care 2022;1. Doi:10.1186\/s44201-022-00006-5.<\/p>\n

Relationship Between Tobacco Product Use and Health-Related Quality of Life Among Individuals With COPD in Waves 1-5 (2013-2019) of the Population Assessment of Tobacco and Health Study.<\/a> Paulin LM<\/strong>, Halenar MJ, Edwards KC, Lauten K, Taylor K, Brunette M<\/strong>, Tanski S<\/strong>, MacKenzie T, Stanton CA, Hatsukami D, Hyland A, Mahoney MC, Niaura R, Trinidad D, Blanco C, Compton W, Gardner LD, Kimmel HL, Cummings KM, Lauterstein D, Roh EJ, Marshall D, Sargent JD<\/strong>. Chronic Obstr Pulm Dis. 2024 Jan 25;11(1):68-82. doi: 10.15326\/jcopdf.2023.0422.
\nPMID: 38113525<\/p>\n

Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR.<\/a>
\nHansel NN, Woo H, Koehler K, Gassett A, Paulin LM<\/strong>, Alexis NE, Putcha N, Lorizio W, Fawzy A, Belz D, Sack C, Barr RG, Martinez FJ, Han MK, Woodruff P, Pirozzi C, Paine R 3rd, Barjaktarevic I, Cooper CB, Ortega V, Zusman M, Kaufman JD. Am J Respir Crit Care Med. 2023 Nov 15;208(10):1042-1051. doi: 10.1164\/rccm.202302-0207OC. PMID: 37523421<\/p>\n

Impact of Nicotine Replacement Therapy on Breast Surgery Outcomes.<\/a>
\nPatel SM, Junn A, Sasson D, Dinis J, Duan K, Islam S, Fucito L, Bernstein SL<\/strong>, Hsia HC.
\nJ Reconstr Microsurg. 2024 Mar;40(3):239-244. doi: 10.1055\/a-2133-1130. Epub 2023 Jul 19.
\nPMID: 37467771<\/p>\n

Childhood Cigarette Smoking and Risk of Chronic Obstructive Pulmonary Disease in Older U.S. Adults.<\/a> Sargent JD<\/strong>, Halenar M, Steinberg AW, Ozga J, Tang Z, Stanton CA, Paulin LM<\/strong>.
\nAm J Respir Crit Care Med. 2023 Aug 15;208(4):428-434. doi: 10.1164\/rccm.202303-0476OC.
\nPMID: 37348105<\/p>\n

A Secondary Analysis of a Preliminary Contingency Management Intervention for Presurgical Cancer Patients: Evaluating Individual Participant Data.<\/a> Sanford BT, Toll BA, Fucito LM, Baker NL, Krishnan-Sarin S, Carpenter MJ, Bernstein SL<\/strong>, Rojewski AM. Nicotine Tob Res. 2023 Aug 19;25(9):1614-1618. doi: 10.1093\/ntr\/ntad071. PMID: 37156634<\/p>\n

Cost-Effectiveness of Smoking Cessation Approaches in Emergency Departments.<\/a>
\nMiller TR, Johnson MB, Dziura JD, Weiss J, Carpenter KM, Grau LE, Pantalon MV, Abroms L, Collins LM, Toll BA, Bernstein SL<\/strong>. Am J Prev Med. 2023 Jul;65(1):39-44. doi: 10.1016\/j.amepre.2023.01.006. Epub 2023 Jan 28. PMID: 36710199<\/p>\n

Successful Optimization of Tobacco Dependence Treatment in the Emergency Department: A Randomized Controlled Trial Using the Multiphase Optimization Strategy.<\/a>
\nBernstein SL<\/strong>, Dziura J, Weiss J, Brooks AH, Miller T, Vickerman KA, Grau LE, Pantalon MV, Abroms L, Collins LM, Toll B. Ann Emerg Med. 2023 Feb;81(2):209-221. doi: 10.1016\/j.annemergmed.2022.08.018. Epub 2022 Dec 28. PMID: 36585318<\/p>\n

Integrating Tobacco Treatment Into Oncology Care: Reach and Effectiveness of Evidence-Based Tobacco Treatment Across National Cancer Institute-Designated Cancer Centers.<\/a>
\nHohl SD, Matulewicz RS, Salloum RG, Ostroff JS, Baker TB, Schnoll R, Warren G, Bernstein SL<\/strong>, Minion M, Lenhoff K, Dahl N, Juon HS, Tsosie U, Fleisher L, D'Angelo H, Ramsey AT, Ashing KT, Rolland B, Nolan MB, Bird JE, Nguyen CVT, Pauk D, Adsit RT, Tindle HA, Shoenbill K, Yeung S, Presant CA, Wiseman KP, Wen KY, Chichester LA, Chen LS. J Clin Oncol. 2023 May. 20;41(15):2756-2766. doi: 10.1200\/JCO.22.00936. Epub 2022 Dec 6. PMID: 36473135<\/p>\n

Smoking Status, Nicotine Medication, Vaccination, and COVID-19 Hospital Outcomes: Findings from the COVID EHR Cohort at the University of Wisconsin (CEC-UW) Study.<\/a>
\nPiasecki TM, Smith SS, Baker TB, Slutske WS, Adsit RT, Bolt DM, Conner KL, Bernstein SL<\/strong>, Eng OD, Lazuk D, Gonzalez A, Jorenby DE, D'Angelo H, Kirsch JA, Williams BS, Nolan MB, Hayes-Birchler T, Kent S, Kim H, Lubanski S, Yu M, Suk Y, Cai Y, Kashyap N, Mathew JP, McMahan G, Rolland B, Tindle HA, Warren GW, An LC, Boyd AD, Brunzell DH, Carrillo V, Chen LS, Davis JM, Deshmukh VG, Dilip D, Ellerbeck EF, Goldstein AO, Iturrate E, Jose T, Khanna N, King A, Klass E, Mermelstein RJ, Tong E, Tsoh JY, Wilson KM, Theobald WE, Fiore MC. Nicotine Tob Res. 2023 May 22;25(6):1184-1193. doi: 10.1093\/ntr\/ntac201. PMID: 36069915<\/p>\n

Correlates of tobacco product initiation among youth and young adults between waves 1-4 of the population assessment of tobacco and Health (PATH) study (2013-2018).<\/a>
\nCooper M, Day HR, Ren C, Oniyide O, Corey CG, Ambrose BK, Michael Cummings K, Sargent J<\/strong>, Niaura R, Pierce JP, Kaufman A, Choi K, Goniewicz ML, Stanton CA, Villanti A, Kasza K, Bansal-Travers M, Silveira ML, Kimmel HL, Hull LC, Koblitz A, Poonai K, Paredes A, Taylor K, Borek N, Hyland AJ. Addict Behav. 2022 Nov;134:107396. doi: 10.1016\/j.addbeh.2022.107396. Epub 2022 Jun 7. PMID: 35749867<\/p>\n

A qualitative study of smokers' assessments of four smoking cessation interventions delivered in a hospital emergency department.<\/a> Grau LE, Jurczak E, Zahid M, Brooks AH, Weiss J, O'Leary TK, Pham T, Bernstein SL<\/strong>. Drug Alcohol Depend. 2022 Aug 1;237:109512. doi: 10.1016\/j.drugalcdep.2022.109512. Epub 2022 May 27. PMID: 35714533<\/p>\n

The effectiveness of smoking cessation interventions for socio-economically disadvantaged women: a systematic review and meta-analysis.<\/a> O'Connell N, Burke E, Dobbie F, Dougall N, Mockler D, Darker C, Vance J, Bernstein SL<\/strong>, Gilbert H, Bauld L, Hayes CB. Syst Rev. 2022 Jun 2;11(1):111. doi: 10.1186\/s13643-022-01922-7. Epub 2022 Jun 2. PMID: 35655281<\/p>\n

Practices, attitudes, and confidence related to tobacco treatment interventions in HIV clinics: a multisite cross-sectional survey.<\/a> Bold KW, Deng Y, Dziura J, Porter E, Sigel KM, Yager JE, Ledgerwood DM, Bernstein SL<\/strong>, Edelman EJ. Transl Behav Med. 2022 Jul 7;12(6):726-733. doi: 10.1093\/tbm\/ibac022. PMID: 35608982<\/p>\n

Proposing a Model of Proactive Outreach to Advance Clinical Research and Care Delivery for Patients Who Use Tobacco.<\/a> Burris JL, Borger TN, Baker TB, Bernstein SL<\/strong>, Ostroff JS, Rigotti NA, Joseph AM. J Gen Intern Med. 2022 Aug;37(10):2548-2552. doi: 10.1007\/s11606-022-07553-x. Epub 2022 Apr 26. PMID: 35474504<\/p>\n

Introduction to the Cancer Center Cessation Initiative Working Groups: Improving Oncology Care and Outcomes by Including Tobacco Treatment.<\/a> Cancer Center Cessation Initiative Coordinating Center and Expert Advisory Panel. Cancer Center Cessation Initiative Coordinating Center and Expert Advisory Panel: Betsy Rolland , Sarah D. Hohl, Mara Minion 1, Robert Adsit, Margaret B. Nolan, Danielle Pauk, Steven L. Bernstein<\/strong>, Jessica L. Burris, Paul M. Cinciripini, Anne Joseph, Jamie Ostroff, Graham W. Warren, Michael C. Fiore. \u00a0J Natl Compr Canc Netw. 2021 Nov;19(Suppl_1):S1-S3. doi: 10.6004\/jnccn.2021.7095. PMID: 34872051<\/p>\n

Preoperative contingency management intervention for smoking abstinence in cancer patients: trial protocol for a multisite randomised controlled trial.\u00a0<\/a>Rojewski AM, Fucito LM, Baker NL, Palmer AM, Foster MG, Warren GW, Bernstein SL<\/strong>, Toll BA. BMJ Open. 2021 Jun 29;11(6):e051226. doi: 10.1136\/bmjopen-2021-051226. Epub 2021 Jun 29. PMID: 34187835<\/p>\n

A Brief Negotiation Interview Adherence Scale for Smoking Cessation: A psychometric evaluation.<\/a> Pantalon MV, Dziura J, Li FY, D'Onofrio G, Weiss J, Bernstein SL<\/strong>. J Subst Abuse Treat. 2021 Jul;126:108398. doi: 10.1016\/j.jsat.2021.108398. Epub 2021 Apr 20. PMID: 34116807<\/p>\n

A SMARTTT approach to Treating Tobacco use disorder in persons with HIV (SMARTTT): Rationale and design for a hybrid type 1 effectiveness-implementation study.\u00a0<\/a>Edelman EJ, Dziura J, Deng Y, Bold KW, Murphy SM, Porter E, Sigel KM, Yager JE, Ledgerwood DM, Bernstein SL<\/strong>. Contemp Clin Trials. 2021 Nov;110:106379. doi: 10.1016\/j.cct.2021.106379. Epub 2021 Mar 29. PMID: 33794354<\/p>\n

COVID-19 Challenges Confronted by Smoking Cessation Clinical Trials for People Living With HIV: The Experience of Grantees of the US National Cancer Institute.\u00a0<\/a>Schnoll R, Bernstein SL<\/strong>, Kaufman A, Gross R, Catz SL, Cioe PA, Hitsman B, Marhefka SL, Pacek LR, Vidrine DJ, Vilardaga R, Edelman EJ, McClure JB, Ashare R, Lockhart E, Crothers K. Nicotine Tob Res. 2021 Aug 18;23(9):1629-1632. doi: 10.1093\/ntr\/ntab035. PMID: 33657227<\/p>\n

A Preoperative Contingency Management Intervention for Smoking Abstinence in Cancer Patients: A Preliminary Randomized Controlled Trial.<\/a> Rojewski AM, Fucito LM, Baker NL, Krishnan-Sarin S, Carpenter MJ, Bernstein SL<\/strong>, Toll BA. Nicotine Tob Res. 2021 May 24;23(6):1064-1067. doi: 10.1093\/ntr\/ntaa266. PMID: 33340400<\/p>\n

The United States National Cancer Institute's Coordinated Research Effort on Tobacco Use as a Major Cause of Morbidity and Mortality among People with HIV.<\/a> Ashare RL, Bernstein SL<\/strong>, Schnoll R, Gross R, Catz SL, Cioe P, Crothers K, Hitsman B, Marhefka SL, McClure JB, Pacek LR, Vidrine DJ, Vilardaga R, Kaufman A, Edelman EJ. Nicotine Tob Res. 2021 Jan 22;23(2):407-410. doi: 10.1093\/ntr\/ntaa155. PMID: 32803251<\/p>\n

Pragmatic Application of the RE-AIM Framework to Evaluate the Implementation of Tobacco Cessation Programs Within NCI-Designated Cancer Centers.<\/a> D'Angelo H, Ramsey AT, Rolland B, Chen LS, Bernstein SL<\/strong>, Fucito LM, Webb Hooper M, Adsit R, Pauk D, Rosenblum MS, Cinciripini PM, Joseph A, Ostroff JS, Warren GW, Fiore MC, Baker TB. Front Public Health. 2020;8:221. doi: 10.3389\/fpubh.2020.00221. Epub 2020 Jun 12. PMID: 32596200<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

The Institute provides a home at Dartmouth for researchers who focus on behavior and non-communicable diseases. We conduct research that has a measurable impact on the risk of these diseases. Tobacco is by far the deadliest commodity. \u00a0The 6 trillion cigarettes produced and consumed each year contribute to millions of [\u2026] <\/p>\n

<\/div>\n

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