{"id":236,"date":"2017-08-25T14:14:32","date_gmt":"2017-08-25T18:14:32","guid":{"rendered":"http:\/\/geiselmed.dartmouth.edu\/huang\/?page_id=236"},"modified":"2026-06-27T15:30:28","modified_gmt":"2026-06-27T19:30:28","slug":"rachel-a-brog","status":"publish","type":"page","link":"https:\/\/geiselmed.dartmouth.edu\/huang\/lab-members\/former-members\/rachel-a-brog\/","title":{"rendered":"Rachel Brog, PhD"},"content":{"rendered":"<p><em><strong>Currently:<\/strong> Cofounder of Eris Biotech<br \/>\nMCB student (Huang Lab)<a href=\"http:\/\/geiselmed.dartmouth.edu\/huang\/wp-content\/uploads\/sites\/7\/2017\/08\/Rachel-Brog-e1503684767941.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-238 alignright\" src=\"http:\/\/geiselmed.dartmouth.edu\/huang\/wp-content\/uploads\/sites\/7\/2017\/08\/Rachel-Brog-e1503684767941-259x300.jpg\" alt=\"\" width=\"235\" height=\"257\" \/><\/a><\/em><\/p>\n<p>&nbsp;<\/p>\n<p>Rachel first became interested in research during my undergraduate studies at Brigham Young University where she was working to characterize novel biomarker for immunotherapy. This is when her love for the jargon-filled, acronym-heavy field of immunology commenced. After graduating with a BS in Molecular Biology at BYU and entry into the MCB program at Dartmouth, Rachel joined the Huang lab in June of 2017 and defended her PhD in 2021. Rachel's research in the Huang lab focused on engineering improved antigen recognition by chimeric antigen receptors (CARs) and expression of immune modulators that transform the tumor microenvironment from immune suppressive to immune activating. She is a co-inventor on a patent application, co-founded the Dartmouth Biotech club and served as Guarini Housing representative. Rachel is currently a scientist at Thunder Biotech in Utah. As a Utah native, she loves riding ATVs in the Rockies and hitting up the local national parks. She also enjoys baking, snowboarding, and playing soccer.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Publications<\/strong><\/p>\n<p><strong>Brog RA<\/strong>, Ferry SL, Schiebout CT, Messier CM, Cook WJ, Abdullah L, Zou J, Kumar P, Sentman CL, Frost HR, Huang YH. Superkine IL2 and IL33 armored CAR T cells reshape the tumor microenvironment and reduce growth of multiple solid tumors. <em>Cancer Immunol Res<\/em>. 2022 doi: 10.1158\/2326-6066.CIR-21-0536. PubMed PMID: 35696724.<\/p>\n<p>Butler SE*, <strong>Brog RA*<\/strong>, Chang CH, Sentman CL, Huang YH, Ackerman ME. Engineering a natural ligand-based CAR: directed evolution of the stress-receptor NKp30. <em>Cancer Immunol Immunother.<\/em> 2021 doi: 10.1007\/s00262-021-02971-y. PMID: 34046711<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"text-indent: 20px;width: auto;padding: 0px 4px 0px 0px;text-align: center;font: bold 11px\/20px 'Helvetica Neue',Helvetica,sans-serif;color: #ffffff;background: #bd081c no-repeat scroll 3px 50% \/ 14px 14px;cursor: pointer\">Save<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Currently: Cofounder of Eris Biotech MCB student (Huang Lab) &nbsp; Rachel first became interested in research during my undergraduate studies at Brigham Young University where she was working to characterize novel biomarker for immunotherapy. This is when her love for the jargon-filled, acronym-heavy field of immunology commenced. After graduating with [\u2026] <\/p>\n<div class=\"clear\"><\/div>\n<p><a class=\"more_link clearfix\" href=\"https:\/\/geiselmed.dartmouth.edu\/huang\/lab-members\/former-members\/rachel-a-brog\/\" rel=\"nofollow\">Read More<\/a><\/p>\n","protected":false},"author":37,"featured_media":0,"parent":95,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-236","page","type-page","status-publish","hentry","author-37"],"_links":{"self":[{"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/pages\/236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/users\/37"}],"replies":[{"embeddable":true,"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/comments?post=236"}],"version-history":[{"count":7,"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/pages\/236\/revisions"}],"predecessor-version":[{"id":496,"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/pages\/236\/revisions\/496"}],"up":[{"embeddable":true,"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/pages\/95"}],"wp:attachment":[{"href":"https:\/\/geiselmed.dartmouth.edu\/huang\/wp-json\/wp\/v2\/media?parent=236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}