{"id":26,"date":"2025-09-09T15:11:22","date_gmt":"2025-09-09T15:11:22","guid":{"rendered":"https:\/\/geiselmed2.dartmouth.edu\/goodrum-lab\/?page_id=26"},"modified":"2026-06-26T16:18:32","modified_gmt":"2026-06-26T16:18:32","slug":"recent-publications","status":"publish","type":"page","link":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/recent-publications\/","title":{"rendered":"Publications"},"content":{"rendered":"Full Publication List@PubMed<\/span><\/a>\n

FEATURED ORIGINAL RESEARCH<\/strong><\/p>\n

Human cytomegalovirus regulates host DNA repair machinery for viral<\/a> genom<\/a>e<\/a> integrity<\/a>. Longmire, P., S. Zeltzer, K. Zarrella, O. Daigle, M. Svoboda, J.M. Reitsma, S.S. Terhune, C. Bobak, G. Bosco, and F. Goodrum<\/strong>. 2026. Nucleic Acids Research<\/em>, 54(2):gkaf1445. PMID:41533576<\/a><\/p>\n

Viral and host network analysis of the human cytomegalovirus transcriptome in latency<\/a>. Collins-McMillen, D., D. De Oliviera-Pessoa, K. Zarrella, N.J. Moorman, J. P. Kamil, P. Caposio, M. Padi, and F.D. Goodrum<\/strong>. 2025.\u00a0 Proc. Natl. Acad. Sci. USA<\/em>,122(22): e2416114122. PMID:40434638<\/a><\/p>\n

Human Cytomegalovirus UL138 Interaction with USP1 Activates STAT1 in Infection<\/a>. Zarrella, K., P. Longmire, S. Zeltzer, D. Collins-McMillen, M. Hancock, J. Buehler, J. Reitsma, J. Nelson, S. S. Terhune, and F. Goodrum<\/strong>. 2023. PLoS Pathogens,<\/em> June 8; 19(6):e1011185. PMID:37289831<\/a><\/p>\n

Host translesion polymerases are required for viral genome integrity<\/a>. Zeltzer, S., P. Longmire, M. Svoboda, G. Bosco, and F. Goodrum<\/strong>. 2022.\u00a0 Proc Natl Acad Sci USA<\/em>, 119(33):e2203203119. PMID: 35947614<\/a><\/p>\n

Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and lat<\/a>ency. Buehler, J., E. Carpenter, S. Zeltzer, S. Igarashi, M. Rak, I. Mikell, J.A. Nelson, and F. Goodrum<\/strong>. 2019.\u00a0 PLoS Pathogens<\/em>, 15<\/strong>(11):e1008037. PMID: 31725811<\/p>\n

Alternative Promoters Drive Human Cytomegalovirus Reactivation from Latency. Collins-McMillen, D., M. Rak, J.C. Buehler, S. Igarashi-Hayes, J.P. Kamil, N.J. Moorman, and F. Goodrum<\/strong>. 2019.\u00a0 Proc Natl Acad Sci USA, <\/em>116<\/strong>(35):17492-17497. PMID: 31409717.<\/p>\n

Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins to Regulate Epidermal Growth Factor Receptor and Reactivation from Latency. Rak, M., J. Buehler, S. Zeltzer, J. Reitsma, S. Terhune, F. Goodrum<\/strong>. 2018.\u00a0 J Virology<\/em>, 92<\/strong>(20): e00919-18. PMID: 30089695<\/p>\n

Virus control of trafficking from sorting endosomes. Zeltzer, S., C. A. Zeltzer, J. Wilson, J. G. Donaldson, and F. Goodrum<\/strong>. 2018. MBio<\/em>, 9<\/strong>(4): e00683-18.<\/em> PMID: 30042195<\/p>\n

FEATURED REVIEWS<\/strong><\/p>\n

DNA Damage Responses in Human Cytomegalovirus Infection: Emerging Mechanisms and Outstanding Questions. Savanagouder, M., P. Longmire, A. Hassan, D. R. McKinzey, R. Dansereau, G. Bosco, and F. Goodrum<\/strong>. 2026.\u00a0J Virology<\/em>, Jun 16:e0037626<\/em>. PMID: 42300770<\/p>\n

Human cytomegalovirus latency \u2013 the sum of subtleties. Hancock, M.H., P. Caposio, D. Collins-McMillen, N.L Diggins, B-.J. Lee, S. Medica, D. N. Streblow, T. White, A.D. Yurochko, F. Goodrum<\/strong>. 2025. J Virology<\/em>, Jul30:e0066425. PMID:40736257<\/p>\n

Virology \u2013 the next fifty years. Holmes, E., F. Krammer, and F. Goodrum<\/strong>. 2024. Cell<\/em>, Sep 19; 187 (19): 5128-5145. PMID:39303682\u00a0 PMC11467463<\/p>\n

The complex biology of human cytomegalovirus latency and reactivation.\u00a0 Goodrum, F.<\/strong> \u00a02022. In Adv.Virus Res. <\/em>v112. <\/em>Aug 1. PMID:35840181<\/p>\n

FEATURED SCIENCE ADVOCACY<\/strong><\/p>\n

Bieniasz, P., C. Rice, T. Dermody, L. Enquist, F. Goodrum<\/strong>, D. Kushner, H. Lazear, S. Lemon, A. Pekosz, J. Purdy, V. Racaniello, T. Schountz, S. Weiss, C. Wobus, J. Alwine, S. Bertuzzi, J. Marrazzo, Shan-Lu-Liu. 2026. Protecting strength and integrity in virology. J Virology<\/em>, in press<\/em>. Published also as a response to Science<\/em> article.<\/p>\n

A call for the United States to continue investing in science. Blader, I. \u2020<\/sup>, F. Goodrum<\/strong>\u2020<\/sup>, M.J. Imperiale\u2020<\/sup>, A. Casadevall, C. Arias, A. Baumler, C.A. Burnham, C. Cuomo, C. Detweiler, G. Forrest, J. Gilbert, S. Lovett, S. Maloy, A. McAdam, I. Newton, G. Reguera, G. O\u2019Toole, P. D. Scloss, A. Shade, M. Whiteley. 2025. mBio<\/em>, Apr 9; 16(4)e0064825. Co-published in J Virology<\/em>, J Bacteriology<\/em>, mSphere<\/em>, mSystems<\/em>, Appl. Env. Micro<\/em>., ASM Case Reports<\/em>, Antimicrobial Agents and Chemotherapy<\/em>, J Clin.Microbiol<\/em>., Microbiol Spectrum<\/em>, Clin. Microbiol. Rev<\/em>., Infection and Immunity<\/em>, Microbiol. Resouce Announcements<\/em>, Microbiol. and Mol. Bio. Rev<\/em>., J Microbiol. and Bio. Educ<\/em>. PMID: 40013856<\/p>\n

The harms of promoting the lab leak hypothesis without evidence. Alwine, J.\u2020<\/sup>, Goodrum<\/strong>\u2020<\/sup>, B. Banfield, D. Bloom, W. J. Britt, A. J. Broadbent, S. K. Campos, A. Casadevall, T. Dermody, W. P. Duprex, L. W. Enquist, K. Frueh, M. Gaglia, A.P. Geballe, et al<\/em> (41 authors total)<\/em>. 2024. J Virology<\/em>, 98(9) Sep 17:e0124024. PMID: 39087765. Notable press: LA Times<\/em>, <\/em>TWiV<\/em>, STAT<\/em><\/p>\n

Virology \u2013 the path forward. Rasmussen, A. \u2020<\/sup>, G. Gronvall\u2020<\/sup>, A. Lowen\u2020<\/sup>, Goodrum<\/strong>\u2020<\/sup>, et al. (79 total authors<\/em><\/strong>)<\/em>. 2024. J Virology<\/em>, 98(1)Jan 3: e0179123. PMID: 38168672\u00a0<\/p>\n

Field research is essential to counter virological threats. Runstadler, J. A., A. C. Lowen, G. Kayeli, S. M. Tompkins, R. A. Albrecht, R. A. M. Fouchier, D. E. Stallknecht, S. S. Lakdawala, F. D. Goodrum<\/strong>, A. Casadevall, L. W. Enquist, J. C. Alwine, M. J. Imperiale, S. Schultz-Cherry, R. J. Webby 2023. J. <\/em>Virology<\/em>. doi:10.1128\/jvi.00544-23:e0054423. PMID:37166327<\/p>\n

A critical analysis of the evidence for the SARS-CoV-2 origin hypotheses. Alwine, J.C., A. Casadevall, L.W. Enquist, D. Goodrum\u2020<\/sup><\/strong>, M.J. Imperiale. 2023.\u00a0 Co-published in: mBio, J Virology, mSphere<\/em>. March 28. \u00a0PMID: 36897089<\/p>\n

Oversight of pathogen research must be carefully calibrated and clearly defined. Lowen, A., A. Casadevall, J.C. Alwine, L.W. Enquist, F.D. Goodrum<\/strong>, M.J. Imperiale, S.S. Lakdawala. 2023.\u00a0 Co-published in: mBio, J Virology, <\/em>and mSphere. <\/em>Feb 22. PMID:36811609.<\/p>\n

Virology under the microscope \u2013 a call for rational discourse. Goodrum, F. \u2020<\/sup><\/strong>, A. Lowen, S. Lakdawala, J. Alwine, A. Casadevall, M. Imperiale, et al.<\/em> (156 total authors<\/em><\/strong>)<\/em>. 2023. Co-published in: mBio, J Virology, <\/em>and 27 Jan. . PMID:\u00a036700640 Notable press: New York Times<\/em>, <\/em>NPR<\/em>, <\/em>Arizona Republic<\/em>, and <\/em>This Week in Virology (TWiV)<\/em><\/p>\n

 <\/p>\nMore Publications@PubMed<\/span><\/a>\n","protected":false},"excerpt":{"rendered":"

DNA damage responses in HCMV infection: emerging mechanisms and outstanding questions.<\/a>
Savanagouder M, Longmire P, Hassan A, McKinzey D, Dansereau R, Bosco G, Goodrum F
J Virol. 2026 Jun 16;:e0037626. doi: 10.1128\/jvi.00376-26. Epub 2026 Jun 16.
PMID: 42300770<\/p>

Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance.<\/a>
Longmire P, Chen H, McKinzey DR, Savanagouder M, Kosarek NN, Pesola JM, Bobak CA, Bosco G, Goodrum F, Coen DM
bioRxiv. 2026 May 22; pii: 2026.05.21.726832. doi: 10.64898\/2026.05.21.726832. Epub 2026 May 22.
PMID: 42239149<\/p>

Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity.<\/a>
Longmire P, Zeltzer S, Zarrella K, Daigle O, Svoboda M, Reitsma JM, Terhune SS, Bobak C, Bosco G, Goodrum F
Nucleic Acids Res. 2026 Jan 14;54(2) doi: 10.1093\/nar\/gkaf1445.
PMID: 41533576<\/p>
\nMore Publications<\/span><\/a>\u00a0<\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-26","page","type-page","status-publish","hentry","author-9"],"_links":{"self":[{"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/pages\/26","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":17,"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/pages\/26\/revisions"}],"predecessor-version":[{"id":342,"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/pages\/26\/revisions\/342"}],"wp:attachment":[{"href":"https:\/\/geiselmed.dartmouth.edu\/goodrum-lab\/wp-json\/wp\/v2\/media?parent=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}