Edit Entry | Edit CV

Robert A Cramer Jr, PhD

Title(s)
Professor of Microbiology and Immunology

Department(s)
Microbiology and Immunology

Education
Lawrence University Appleton, WI - BA Biology 1999
Colorado State University, MSc - 2001
Colorado State University, PhD - 2004
Duke University Medical Center, Post-Doctoral Fellow 2007

Programs
Immunology Program
Molecular and Cellular Biology Graduate Programs
Molecular Pathogenesis Program

Websites
https://geiselmed.dartmouth.edu/cramer/

Academic Analytics
View Profile

Contact Information

74 College Street Vail Loading Dock
Remsen 213
Hanover NH 03755

Office: Remsen 208
Phone: (603)650-1040
Email: Robert.A.Cramer.Jr@Dartmouth.edu

Professional Interests

Fungi, Fungal pathogenesis and Virulence, hypoxia, oxygen, innate immunity, metabolism, host-pathogen interactions, lung, cystic fibrosis, regulated cell death, antifungal drugs, biofilms

Rotations and Thesis Projects

Please see our laboratory website: https://geiselmed.dartmouth.edu/cramer/

Grant Information

National Institutes of Health, NIAID
Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Diseases Fellow
Cystic Fibrosis Research Foundation

Biography

Please see our laboratory web site.

Selected Publications
 

  • Kowalski CH, Kerkaert JD, Liu KW, Bond MC, Hartmann R, Nadell CD, Stajich JE, Cramer RA Fungal biofilm morphology impacts hypoxia fitness and disease progression. Nature Microbiology (view details in PubMed)

  • Beattie SR, Mark KMK, Thammahong A, Ries LNA, Dhingra S, Caffrey-Carr AK, Cheng C, Black CC, Bowyer P, Bromley MJ, Obar JJ, Goldman GH, Cramer RA. Filmentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression. PLoS Pathogens (view details in PubMed)

  • Kowalski CH, Beattie SR, Fuller KK, McGurk EA, Tang YW, Hohl TM, Obar JJ, Cramer RA Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence. mBIO (view details in PubMed)

  • Chung D, Barker BM, Carey CC, Merriman B, Werner ER, Lechner BE, Dhingra S, Cheng C, Xu W, Blosser SJ, Morohashi K, Mazurie A, Mitchell TK, Haas H, Mitchell AP, Cramer RA ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence. PLoS Pathogens (view details in PubMed)

  • Shepardson KM, Jhingran A, Caffrey A, Obar JJ, Suratt BT, Berwin BL, Hohl TM, Cramer RA Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection. PLoS Pathogens (view details in PubMed)

  • Shlezinger N, Irmer H, Dhingra S, Beattie SR, Cramer RA, Braus GH, Sharon A, Hohl TM Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death. Science (view details in PubMed)

  • Thammahong A, Caffrey-Card AK, Dhingra S, Obar JJ, Cramer RA Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity. mBIO (view details in PubMed)

  • Caffrey-Carr AK, Kowalski CH, Beattie SR, Blaseg NA, Upshaw CR, Thammahong A, Lust HE, Tang YW, Hohl TM, Cramer RA, Obar JJ Interleukin 1α Is Critical for Resistance against Highly Virulent Aspergillus fumigatus Isolates. Infection and Immunity (view details in PubMed)

    		•