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Charles R Thomas Jr, MD

Professor of Medicine

Additional Titles/Positions/Affiliations
Chief, Radiation Oncology

Deputy Editor, JAMA Oncology

Advisory Board, Dartmouth Undergraduate Journal of Science (DUJS)


Dartmouth College, BA, 1979
University of Illinois College of Medicine, MD, 1985

Norris Cotton Cancer Center

Curriculum Vitae

NIH Biosketch



Instagram: @dartmouthradonc

PubMed citations:








Academic Analytics
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Contact Information

1 Medical Center Drive
2K, Room 263L5
Lebanon NH 03756

Office: 236L5
Phone: 603-650-6674
Fax: 603-640-6844
Email: Charles.R.Thomas.Jr@Dartmouth.edu

Assistant: Carrie Hertel
Asst. Phone: 603-650-6686
Asst. Email: Carrie.D.Hertel@Hitchcock.org

Professional Interests

Area(s) of Research/Scholarly Interest:

1) Protocol development of translational research-based national cooperative group combined modality therapeutic clinical trials for GI and thoracic solid tumors
2) Development of strategies to address barriers to participation in cancer clinical trials amongst minority and ethnic populations in the U.S.
3) Mediastinal tumors
4) SMMART (Serial Measurements of Molecular Architecture Responses to Therapy) trials, including radiomics as a tool to increase the therapeutic ratio in radiation oncology
5) Pre-clinical & clinical characterization of the interaction between novel systemic therapeutics and ionizing radiation
6) Cancer emergency medicine; https://link.springer.com/book/10.1007/978-3-030-67123-5

1) Mentorship in Academic Radiation Oncology


2) Development of pipeline strategies to increase URM investigators into radiologic sciences and cancer medicine
3) Patient-Provider Communication
4) Burnout Assessment & Management in Academic Leaders
5) Interaction of Mentoring and Academic Productivity; https://cancer.dartmouth.edu/stories/article/building-culture-mentorship-dartmouth-cancer-center

Rotations and Thesis Projects

Pending update

Grant Information

Pending update

Courses Taught

Geisel Elective-248, Topics in Radiation Oncology (Fall, 2022)

ENG 56, Introduction to Biomedical Engineering (Spring, 2022, Spring 2023)

Mentoring Information





Charles R. Thomas, Jr., M.D., is Professor and Chief, Radiation Oncology at the Dartmouth Cancer Center. He previously served as Prof. & Chair of the Dept. of Radiation Medicine @ the Knight Cancer Institute/Oregon Health & Science University. Dr. Thomas has received triple-board certification in Radiation Oncology (American Board of Radiology), Medical Oncology and Internal Medicine (American Board of Internal Medicine). He attended the 1998 Vail course as a student and later taught @ the Vail Workshop from 2009-12, as well as the Flims/Zeist clinical trials workshop from 2012-2017. Dr. Thomas has serves on the NCI Rectal-Anal Cancer Task Force. He is also active in protocol development either as chair or co-chair, within the U.S. cooperative group mechanism, with a focus on novel therapeutic translational clinical research on GI and thoracic malignancies that have tested incorporation of novel antiproliferative systemic agents with radiotherapy. Dr. Thomas has served as the chair of the Radiation Oncology Committee of the American College of Surgeons Oncology Group (ACOSOG). He is currently Deputy Editor of JAMA Oncology and has served as Editor-in-Chief of Radiation Medicine Rounds (Demos Medical Publishing), as well as on the Editorial Boards of the Seminars in Radiation Oncology, Advances in Radiation Oncology, Journal of Clinical Oncology, Journal of Gastrointestinal Oncology, Diseases of the Esophagus, Radiographics, and CA: A Cancer Journal for Clinicians. Dr. Thomas has served as an oral and written examiner for the GI section of The American Board of Radiology Certification Examination, as well as on multiple committees within ASCO (Grants Selection Committee, Membership Committee past-chair, Scientific Program Committee), RSNA (past chair, Radiation Oncology Study Section), and ASTRO (Nominating Committee, Science Council Steering Committee, Bylaws & Constitution Committee, Membership Committee, Scientific Program Committee & GI Abstract Review Committee). Dr. Thomas has served as chair of the Grant Writing Workshop for the 2017-2020 annual ASCO meeting. He is the author or co-author of over 350 journal articles & editorials and is a co-editor of multiple textbooks including Oncologic Emergency Medicine: Principles & Practice (Springer, 2nd ed), Career Development in Academic Radiation Oncology (Springer, 2021), Mediastinal Tumors (Springer), Biliary Tract & Gallbladder Cancers: Diagnosis and Therapy (2 editions, Springer & Demos Medical Publishing), and Esophagus Cancers: Practice and Principles (1st ed 2009, 2nd ed 2021). Dr. Thomas has received funding from the NIH, NSF, foundations, & industry. In 2022, he was a recipient of the ASTRO Mentoring Award.

Selected Publications


Selection and Prejudice: Addressing Clinical Trial Disparities With a Review of Current Shortcomings and Future Directions.
Corrigan KL, Rooney MK, Kouzy R, Manzar G, Thomas CR Jr, Ludmir EB
Semin Radiat Oncol. 2023 Oct;33(4):367-373. doi: 10.1016/j.semradonc.2023.06.002.
PMID: 37684066

In Reply to Shueng et al.
Mattes MD, Thomas CR Jr, Deville C Jr
Int J Radiat Oncol Biol Phys. 2023 Oct 1;117(2):516-517. doi: 10.1016/j.ijrobp.2023.05.041.
PMID: 37652612

Effects of UHDR and Conventional Irradiation on Behavioral and Cognitive Performance and the Percentage of Ly6G+ CD45+ Cells in the Hippocampus.
Chaklai A, Canaday P, O'Niel A, Cucinotta FA, Sloop A, Gladstone D, Pogue B, Zhang R, Sunnerberg J, Kheirollah A, Thomas CR Jr, Hoopes PJ, Raber J
Int J Mol Sci. 2023 Aug 6;24(15) doi: 10.3390/ijms241512497. Epub 2023 Aug 6.
PMID: 37569869

Thomas CR Jr
Hematol Oncol Clin North Am. 2024 Feb;38(1):xvii. doi: 10.1016/j.hoc.2023.06.006. Epub 2023 Jul 7.
PMID: 37423822

Incidence of Primary End Point Changes Among Active Cancer Phase 3 Randomized Clinical Trials.
Florez MA, Jaoude JA, Patel RR, Kouzy R, Lin TA, De B, Beck EJ, Taniguchi CM, Minsky BD, Fuller CD, Lee JJ, Kupferman M, Raghav KP, Overman MJ, Thomas CR Jr, Ludmir EB
JAMA Netw Open. 2023 May 1;6(5):e2313819. doi: 10.1001/jamanetworkopen.2023.13819. Epub 2023 May 1.
PMID: 37195664

Society for Women in Radiation Oncology Consensus Statement on Family and Medical Leave.
Baniel CC, Ponce SB, Lichter KE, Peters GW, Small C, Seldon C, Nguyen KT, Khan AF, Thomas CR Jr, Small W Jr, Kahn JM, Olivier KR, Masters AH, Barry PN, Pollom EL, Jagsi R
Int J Radiat Oncol Biol Phys. 2023 Jun 1;116(2):270-275. doi: 10.1016/j.ijrobp.2022.12.027.
PMID: 37179087

CRT Maxims for the Department Chair Role in Inclusiveness in Academic Radiation Oncology.
Thomas CR Jr
Int J Radiat Oncol Biol Phys. 2023 Jun 1;116(2):229-231. doi: 10.1016/j.ijrobp.2022.06.099.
PMID: 37179086

Phase 2 study of preoperative chemotherapy with nab-paclitaxel and gemcitabine followed by chemoradiation for borderline resectable or node-positive pancreatic ductal adenocarcinoma.
Chen EY, Kardosh A, Nabavizadeh N, Foster B, Mayo SC, Billingsley KG, Gilbert EW, Lanciault C, Grossberg A, Bensch KG, Maynard E, Anderson EC, Sheppard BC, Thomas CR Jr, Lopez CD, Vaccaro GM, OHSU Gastrointestinal Cancer Disease Group
Cancer Med. 2023 Jun;12(12):12986-12995. doi: 10.1002/cam4.5971. Epub 2023 May 3.
PMID: 37132281

Consensus Quality Measures and Dose Constraints for Lung Cancer From the Veterans Affairs Radiation Oncology Quality Surveillance Program and ASTRO Expert Panel.
Puckett LL, Titi M, Kujundzic K, Dawes SL, Gore EM, Katsoulakis E, Park JH, Solanki AA, Kapoor R, Kelly M, Palta J, Chetty IJ, Jabbour SK, Liao Z, Movsas B, Thomas CR Jr, Timmerman RD, Werner-Wasik M, Kudner R, Wilson E, Simone CB 2nd
Pract Radiat Oncol. 2023 Sep-Oct;13(5):413-428. doi: 10.1016/j.prro.2023.04.003. Epub 2023 Apr 18.
PMID: 37075838

Pilot Study Exploring the Feasibility of Incorporating Radiation Oncology Into Pre-existing Early Pathway Programs for Diverse Premedical Students.
Mattes MD, Munoz SM, Thomas CR Jr, Deville C Jr
Int J Radiat Oncol Biol Phys. 2023 Aug 1;116(5):992-998. doi: 10.1016/j.ijrobp.2023.01.023. Epub 2023 Jan 23.
PMID: 36702316

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