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Charles R Thomas Jr, MD

Professor of Medicine

Additional Titles/Positions/Affiliations
Chief, Radiation Oncology

Deputy Editor, JAMA Oncology

Advisory Board, Dartmouth Undergraduate Journal of Science (DUJS)


Dartmouth College, BA, 1979
University of Illinois College of Medicine, MD, 1985

Dartmouth Cancer Center

Curriculum Vitae

NIH Biosketch




Instagram: @dartmouthradonc

PubMed citations:








Academic Analytics
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Contact Information

1 Medical Center Drive
2K, Room 263L5
Lebanon NH 03756

Office: 236L5
Phone: 603-650-6674
Fax: 603-640-6844
Email: Charles.R.Thomas.Jr@Dartmouth.edu

Assistant: Carrie Hertel
Asst. Phone: 603-650-6686
Asst. Email: Carrie.D.Hertel@Hitchcock.org

Professional Interests

Area(s) of Research/Scholarly Interest:

1) Protocol development of translational research-based national cooperative group combined modality therapeutic clinical trials for GI and thoracic solid tumors
2) Development of strategies to address barriers to participation in cancer clinical trials amongst minority and ethnic populations in the U.S.
3) Mediastinal tumors
4) SMMART (Serial Measurements of Molecular Architecture Responses to Therapy) trials, including radiomics as a tool to increase the therapeutic ratio in radiation oncology
5) Pre-clinical & clinical characterization of the interaction between novel systemic therapeutics and ionizing radiation
6) Cancer emergency medicine; https://link.springer.com/book/10.1007/978-3-030-67123-5

1) Mentorship in Academic Radiation Oncology


2) Development of pipeline strategies to increase URM investigators into radiologic sciences and cancer medicine
3) Patient-Provider Communication
4) Burnout Assessment & Management in Academic Leaders
5) Interaction of Mentoring and Academic Productivity; https://cancer.dartmouth.edu/stories/article/building-culture-mentorship-dartmouth-cancer-center

Rotations and Thesis Projects

Pending update

Grant Information

Pending update

Courses Taught

Geisel Elective-248, Topics in Radiation Oncology (Fall, 2022)

ENG 56, Introduction to Biomedical Engineering (Spring, 2022, Spring 2023, Spring 2024)

MEDI-522, Introduction to Radiation Oncology

MEDI-555, Advanced Clerkship in Radiation Oncology

Mentoring Information





Charles R. Thomas, Jr., M.D., is Professor and Founding Chair, Dept. of Radiation Oncology & Applied Sciences (July 2024) at the Geisel School of Medicine and Dartmouth Cancer Center. He previously served as Prof. & Chair of the Dept. of Radiation Medicine @ the Knight Cancer Institute/Oregon Health & Science University. Dr. Thomas has received triple-board certification in Radiation Oncology (American Board of Radiology), Medical Oncology and Internal Medicine (American Board of Internal Medicine). He attended the 1998 Vail course as a student and later taught @ the Vail Workshop from 2009-12, as well as the Flims/Zeist clinical trials workshop from 2012-2017. Dr. Thomas has served on the NCI Rectal-Anal Cancer Task Force. He is also active in protocol development either as chair or co-chair, within the U.S. cooperative group mechanism, with a focus on novel therapeutic translational clinical research on GI and thoracic malignancies that have tested incorporation of novel antiproliferative systemic agents with radiotherapy. Dr. Thomas has served as the chair of the Radiation Oncology Committee of the American College of Surgeons Oncology Group (ACOSOG). He is currently Deputy Editor of JAMA Oncology and has served as Editor-in-Chief of Radiation Medicine Rounds (Demos Medical Publishing), as well as on the Editorial Boards of the Seminars in Radiation Oncology, Advances in Radiation Oncology, Journal of Clinical Oncology, Journal of Gastrointestinal Oncology, Diseases of the Esophagus, Radiographics, and CA: A Cancer Journal for Clinicians. Dr. Thomas has served as an oral and written examiner for the GI section of The American Board of Radiology Certification Examination, as well as on multiple committees within ASCO (Grants Selection Committee, Membership Committee past-chair, Scientific Program Committee), RSNA (past chair, Radiation Oncology Study Section), and ASTRO (Nominating Committee, Science Council Steering Committee, Bylaws & Constitution Committee, Membership Committee, Scientific Program Committee & GI Abstract Review Committee). Dr. Thomas has served as chair of the Grant Writing Workshop for the 2017-2020 annual ASCO meeting. He is the author or co-author of over 360 journal articles & editorials and is a co-editor of multiple textbooks including Oncologic Emergency Medicine: Principles & Practice (Springer, 2nd ed), Career Development in Academic Radiation Oncology (Springer, 2021), Absolute Therapeutic Medical Physics Review (Springer, 2022), Mediastinal Tumors (Springer), Biliary Tract & Gallbladder Cancers: Diagnosis and Therapy (2 editions, Springer & Demos Medical Publishing), and Esophagus Cancers: Practice and Principles (1st ed 2009, 2nd ed 2021). Dr. Thomas has received funding from the NIH, NSF, foundations, & industry. In 2022, he was a recipient of the ASTRO Mentoring Award.

Selected Publications


Disease Site Specialization in the Academic Radiation Oncology Workforce: Evidence of Gender Differences.
Corrigan KL, Bankston ME, Holliday EB, Shaitelman SF, Lee A, Goodman CR, Fuller CD, Chino FL, Thomas CR Jr, Jagsi R, Ludmir EB
Int J Radiat Oncol Biol Phys. 2024 Jun 17; pii: S0360-3016(24)00736-3. doi: 10.1016/j.ijrobp.2024.06.004. Epub 2024 Jun 17.
PMID: 38897359

Anesthetic Oxygen Use and Sex Are Critical Factors in the FLASH Sparing Effect.
Tavakkoli AD, Clark MA, Kheirollah A, Sloop AM, Soderholm HE, Daniel NJ, Petusseau AF, Huang YH, Thomas CR Jr, Jarvis LA, Zhang R, Pogue BW, Gladstone DJ, Hoopes PJ
Adv Radiat Oncol. 2024 Jun;9(6):101492. doi: 10.1016/j.adro.2024.101492. Epub 2024 Mar 13.
PMID: 38711960

Empirically Derived Principles for Research Funding Success: A Primer for Early Career Academic Investigators.
Wahid KA, Rooney MK, Gunther JR, Moreno AC, Pinnix CC, Thomas CR Jr, Fuller CD
Int J Radiat Oncol Biol Phys. 2024 Mar 1;118(3):590-594. doi: 10.1016/j.ijrobp.2023.09.030.
PMID: 38340768

Association of differential censoring with survival and suboptimal control arms among oncology clinical trials.
Hsu EJ, Lin TA, Dabush DR, McCaw Z, Koong A, Lin C, Abi Jaoude J, Patel R, Kouzy R, El Alam MB, Noticewala S, Yang Y, Sherry AD, Fuller CD, Thomas CR Jr, Tang C, Msaouel P, Das P, Huang B, Tian L, Sun R, Lee JJ, Meirson T, Ludmir EB
J Natl Cancer Inst. 2024 Jun 7;116(6):990-994. doi: 10.1093/jnci/djae028.
PMID: 38331394

Can I Leave? Perspectives on Parental Leave and Parenthood in Medical Training Among Program Directors and Trainees in Oncologic Specialties.
Beltran Ponce S, Jagsi R, Florez N, Thomas CR Jr, Banerjee A, Jasti S, Bailey MM, Lawton CAF, Johnstone C, Clarke CN, Bedi M, Jovanovic M, Saeed H
J Womens Health (Larchmt). 2024 Feb;33(2):218-227. doi: 10.1089/jwh.2023.0200. Epub 2023 Nov 21.
PMID: 38011014

Disparities in outcomes and access to therapy options in hepatocellular carcinoma.
Beltran Ponce S, Gokun Y, Douglass F, Dawson L, Miller E, Thomas CR Jr, Pitter K, Conteh L, Diaz DA
J Natl Cancer Inst. 2024 Feb 8;116(2):264-274. doi: 10.1093/jnci/djad213.
PMID: 37831897

Selection and Prejudice: Addressing Clinical Trial Disparities With a Review of Current Shortcomings and Future Directions.
Corrigan KL, Rooney MK, Kouzy R, Manzar G, Thomas CR Jr, Ludmir EB
Semin Radiat Oncol. 2023 Oct;33(4):367-373. doi: 10.1016/j.semradonc.2023.06.002.
PMID: 37684066

In Reply to Shueng et al.
Mattes MD, Thomas CR Jr, Deville C Jr
Int J Radiat Oncol Biol Phys. 2023 Oct 1;117(2):516-517. doi: 10.1016/j.ijrobp.2023.05.041.
PMID: 37652612

Effects of UHDR and Conventional Irradiation on Behavioral and Cognitive Performance and the Percentage of Ly6G+ CD45+ Cells in the Hippocampus.
Chaklai A, Canaday P, O'Niel A, Cucinotta FA, Sloop A, Gladstone D, Pogue B, Zhang R, Sunnerberg J, Kheirollah A, Thomas CR Jr, Hoopes PJ, Raber J
Int J Mol Sci. 2023 Aug 6;24(15) doi: 10.3390/ijms241512497. Epub 2023 Aug 6.
PMID: 37569869

Thomas CR Jr
Hematol Oncol Clin North Am. 2024 Feb;38(1):xvii. doi: 10.1016/j.hoc.2023.06.006. Epub 2023 Jul 7.
PMID: 37423822

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