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Anna N. A. Tosteson, ScD

Professor of Medicine
Professor of Community and Family Medicine
Interim Director and Professor of The Dartmouth Institute
James J. Carroll 1948 Professor of Oncology

Additional Titles/Positions/Affiliations:
Director, Comparative Effectiveness Research Program, The Dartmouth Institute for Health Policy and Clinical Practice
Associate Director for Population Sciences, Norris Cotton Cancer Center
Associate Director, SYNERGY, Dartmouth's Clinical and Translational Science Institute
Director, Multidisciplinary Clinical Research Center in Musculoskeletal Diseases

Community and Family Medicine
The Dartmouth Institute

Biostatistics (Health Decision Sciences), Harvard University, ScD
Biostatistics, Harvard University, MS
Statistics & Biometry, Cornell University, BS

Norris Cotton Cancer Center
The Dartmouth Institute for Health Policy and Clinical Practice

Contact Information:

Dartmouth Medical School
HB 7505
One Medical Center Drive
Lebanon NH 03756

Office: WTRB 512, DHMC
Phone: 603-653-3568

Assistant: Christopher Jacobs
Asst. Phone: 603-653-0802
Asst. Email: Christopher.R.Jacobs@Dartmouth.EDU

Professional Interests:

Dr. Tosteson's research addresses clinical and health policy issues in cancer and musculoskeletal diseases through decision-analytic modeling, economic evaluation, and health services research. She is an active participant in national and international groups that focus on the economic evaluation of both new and established health care technologies. Her methodological interests include decision-analytic modeling, comparative effectiveness research, and statistical methods for diagnostic technology assessment. She is a senior faculty member of The Dartmouth Institute for Health Policy & Clinical Practice, where she directs the Comparative Effectiveness Research Program and the affiliated Multidisciplinary Clinical Research Center in Musculosekeletal Diseases. At Norris Cotton Cancer Center, she directs the Office of Cancer Comparative Effectiveness Research and co-directs the Cancer Control Research Program.

Grant Information:

Comparative Effectiveness of Advanced Imaging in Cancer (NCI, Grand Opportunity Grant)

Comparative Effectiveness of Degenerative Spine Disease Treatments (AHRQ)

Spine Patient Outcomes Research Trial (NIAMS)

NIAMS Multidisciplinary Clinical Research Center in Musculoskeletal Diseases (NIAMS)

PROSPR (Population-based optimizing screening through personalized regimens) Breast Cancer Screening Center (NCI)

Comparative Effectiveness Core for P01 on Risk-based Breast Cancer Screening (NCI)

Courses Taught:

ECS 119/121 Decision and Cost-Effectiveness Analysis
ECS 290 Doctoral Seminar Module on Issues in Economic Evaluation

Selected Publications:


  • Tosteson ANA, Stout NK, Fryback DG, Acharyya S, Herman BA, Hannah LG, Pisano ED Cost-effectiveness of digital mammography breast cancer screening. Ann Intern Med 2008; 148:1-10.

  • Tosteson ANA, Melton LJ, Dawson-Hughes B, Bain S, Favus MJ, Khosla S, Lindsay RL. Cost-effective osteoporosis treatment thresholds: The United States Perspective from the National Osteoporosis Foundation Guide Committee. Osteoporos Int 2008;19:437-447.

  • Tosteson ANA, Gottlieb DJ, Radley D, Fisher ES, Melton LJ. Excess mortality following hip fracture: The role of underlying health status. Osteoporos Int 2007; 18;1463-1472.

  • Tosteson ANA, Lurie JD, Tosteson TD, Skinner JS, Herkowitz H, Albert T, Boden SD, Bridwell K, Longley M, Andersson GB, Blood EA, Grove MR, Weinstein JN. Surgical Treatment of Spinal Stenosis with and without Degenerative Spondylolisthesis: Cost-effectiveness after 2 Years in the Spine Patient Outcomes Research Trial. Ann Intern Med 2008; 149:845-853.