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Caitlin G Howe, PhD

Title(s)
Assistant Professor of Epidemiology

Additional Titles/Positions/Affiliations
Adjunct Research Assistant Professor (University of Southern California)

Department(s)
Epidemiology

Education
Columbia University (PhD), 2016
Pomona College (BA), 2009

Programs
Quantitative Biomedical Sciences

Contact Information

1 Medical Center Drive
Lebanon NH 03766

Email: Caitlin.G.Howe@Dartmouth.edu


Professional Interests

Dr. Howe’s research focuses on toxic metal exposures and their impacts on maternal and child health, with a particular interest in effects on early life growth and cardiometabolic health. Additional areas of interest include epigenetic mediators of toxicant exposures and metals toxicity in the context of nutritional status and complex environmental mixtures.

Grant Information

Prenatal Metal Mixtures, Fetal Growth, and the Role of MicroRNAs (NIEHS)

Biography

Professor Howe received her BA in 2009 from Pomona College, with a major in Biology and a minor in Spanish. After graduating, she worked at Fox Chase Cancer Center in an ovarian cancer research lab. She subsequently pursued a PhD in Environmental Health Sciences at Columbia University's Mailman School of Public Health. After receiving her PhD in 2016, she completed a postdoctoral research fellowship in the Department of Preventive Medicine at the University of Southern California. In 2020, she was appointed to the faculty at the Geisel School of Medicine.


Selected Publications

 

Prenatal exposure to essential and toxic elements in relation to infant growth trajectories.
Yim G, Heggeseth BC, Gilbert-Diamond D, Peacock JL, Margetaki K, Baker ER, Palys TJ, Jackson BP, Madan JC, Romano ME, Karagas MR, Howe CG
Environ Health. 2026 Jan 9; doi: 10.1186/s12940-025-01252-w. Epub 2026 Jan 9.
PMID: 41514328

Association of deep learning-derived histologic features of placental chorionic villi with maternal and infant characteristics in the New Hampshire birth cohort study.
Anderson EC, Srinivasan G, Howe CG, Zhang E, Jeon C, Gupta Paruchuri GS, Zhang L, Hwang L, Sengar A, Reddy N, Karan A, Chen A, Shen J, Owo O, Caraballo-Bobea Z, Khatchikian C, Palys TJ, Vaickus LJ, Yao K, Medeiros F, Nguyen H, Madan JC, Karagas MR, Bentz JL, Levy JJ
Placenta. 2025 Oct;170:87-96. doi: 10.1016/j.placenta.2025.07.084. Epub 2025 Jul 23.
PMID: 40902262

Maternal Diet Quality in Pregnancy and Human Milk Extracellular Vesicle and Particle microRNA.
Muse ME, Wang Y, Gilbert-Diamond D, Armstrong DA, Hoen AG, Romano ME, Gui J, Palys TJ, Kolling FW, Christensen BC, Karagas MR, Howe CG
Epigenet Rep. 2025;3(1):1-10. doi: 10.1080/28361512.2025.2508883. Epub 2025 May 30.
PMID: 40631350

Public Water Arsenic and Birth Outcomes in the Environmental Influences on Child Health Outcomes Cohort.
Nigra AE, Bloomquist TR, Rajeev T, Burjak M, Casey JA, Goin DE, Herbstman JB, Ornelas Van Horne Y, Wylie BJ, Cerna-Turoff I, Braun JM, McArthur KL, Karagas MR, Ames JL, Sherris AR, Bulka CM, Padula AM, Howe CG, Fry RC, Eaves LA, Breton CV, Cassidy-Bushrow AE, Lewis J, MacKenzie D, Beene D, Farzan SF, Sathyanarayana S, Hipwell AE, Morello-Frosch R, Snyder BM, Hartert TV, Elliott AJ, O'Connor TG, Kress AM, ECHO Cohort Consortium
JAMA Netw Open. 2025 Jun 2;8(6):e2514084. doi: 10.1001/jamanetworkopen.2025.14084. Epub 2025 Jun 2.
PMID: 40522663

Blood Pressure and Late Pregnancy Circulating miRNAs in the MADRES Study.
Anderson EC, Muse ME, Niu Z, Foley HB, Levy JJ, Romano ME, Gui J, Bentz JL, Farzan SF, Bastain TM, Marsit CJ, Breton CV, Howe CG
J Am Heart Assoc. 2025 Jun 17;14(12):e040416. doi: 10.1161/JAHA.124.040416. Epub 2025 Jun 11.
PMID: 40497511

Maternal Cardiometabolic Risk Factors in Pregnancy and Offspring Blood Pressure at Age 2 to 18 Years.
Niu Z, Ako AA, Geiger SD, Howe CG, Perng W, Singh R, Karagas MR, Elliott AJ, Cassidy-Bushrow A, Camargo CA, Sanderson K, McEvoy CT, Oken E, Dabelea D, Hartert TV, Carter B, Stroustrup A, Lampland A, O'Connor TG, Gogcu S, Hudak ML, Shorey-Kendrick LE, Zhao Q, Ni Y, VanWormer J, Ferrara A, Hedderson M, Zhu Y, Alshawabkeh A, Cordero J, Koinis-Mitchell D, Carnell S, Breton CV, Bastain TM, Farzan SF, ECHO Cohort Consortium
JAMA Netw Open. 2025 May 1;8(5):e259205. doi: 10.1001/jamanetworkopen.2025.9205. Epub 2025 May 1.
PMID: 40338548

Association of Deep Learning-Derived Histologic Features of Placental Chorionic Villi with Maternal and Infant Characteristics in the New Hampshire Birth Cohort Study.
Anderson EC, Srinivasan G, Howe CG, Zhang E, Jeon C, Paruchuri GSG, Zhang L, Hwang L, Sengar A, Reddy N, Karan A, Chen A, Shen J, Owo O, Caraballo-Bobea Z, Khatchikian C, Palys TJ, Vaickus LJ, Madan JC, Karagas MR, Bentz JL, Levy JJ
medRxiv. 2025 Apr 23; pii: 2025.04.22.25325465. doi: 10.1101/2025.04.22.25325465. Epub 2025 Apr 23.
PMID: 40313259

Prenatal per- and polyfluoroalkyl substance mixtures and weight for length from birth to 12 months: The New Hampshire Birth Cohort Study.
Yim G, Howe CG, Gallagher LG, Gilbert-Diamond D, Calafat AM, Botelho JC, Karagas MR, Romano ME
Sci Total Environ. 2025 Jun 10;980:179446. doi: 10.1016/j.scitotenv.2025.179446. Epub 2025 Apr 30.
PMID: 40311330

Optimizing Protocols for MicroRNA Profiling of Infant and Toddler Stool.
Armstrong DA, Soucy SM, Muse ME, Kolling FW, Trask HW, Howell AL, Laue HE, Hoen AG, Gui J, Christensen BC, Madan JC, Karagas MR, Howe CG
bioRxiv. 2025 Apr 3; pii: 2025.04.01.646630. doi: 10.1101/2025.04.01.646630. Epub 2025 Apr 3.
PMID: 40236248

An assessment of organophosphate ester mixtures and the placental transcriptome.
Lapehn S, Parenti M, Firsick EJ, Khodasevich D, Baker BH, Day DB, MacDonald JW, Bammler TK, Kannan K, Choi HY, Barrett ES, Howe CG, Carroll KN, LeWinn KZ, Zhao Q, Cardenas A, Szpiro AA, Sathyanarayana S, Paquette AG
Environ Int. 2025 Apr;198:109402. doi: 10.1016/j.envint.2025.109402. Epub 2025 Mar 19.
PMID: 40132437

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