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Caitlin G Howe, PhD

Assistant Professor of Epidemiology

Additional Titles/Positions/Affiliations:
Adjunct Research Assistant Professor (University of Southern California)


Columbia University (PhD), 2016
Pomona College (BA), 2009

Quantitative Biomedical Sciences

Contact Information:

1 Medical Center Drive
Lebanon NH 03766


Professional Interests:

Dr. Howe’s research focuses on toxic metal exposures and their impacts on maternal and child health, with a particular interest in effects on early life growth and cardiometabolic health. Additional areas of interest include epigenetic mediators of toxicant exposures and metals toxicity in the context of nutritional status and complex environmental mixtures.

Grant Information:

Prenatal Metal Mixtures, Fetal Growth, and the Role of MicroRNAs (NIEHS)


Professor Howe received her BA in 2009 from Pomona College, with a major in Biology and a minor in Spanish. After graduating, she worked at Fox Chase Cancer Center in an ovarian cancer research lab. She subsequently pursued a PhD in Environmental Health Sciences at Columbia University's Mailman School of Public Health. After receiving her PhD in 2016, she completed a postdoctoral research fellowship in the Department of Preventive Medicine at the University of Southern California. In 2020, she was appointed to the faculty at the Geisel School of Medicine.

Selected Publications:


Prenatal metal mixtures and child blood pressure in the Rhea mother-child cohort in Greece.
Howe CG, Margetaki K, Vafeiadi M, Roumeliotaki T, Karachaliou M, Kogevinas M, McConnell R, Eckel SP, Conti DV, Kippler M, Farzan SF, Chatzi L
Environ Health. 2021 Jan 6;20(1):1. doi: 10.1186/s12940-020-00685-9. Epub 2021 Jan 6.
PMID: 33407552

Prenatal Metal Mixtures and Birth Weight for Gestational Age in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles.
Howe CG, Claus Henn B, Eckel SP, Farzan SF, Grubbs BH, Chavez TA, Hodes TL, Faham D, Al-Marayati L, Lerner D, Quimby A, Twogood S, Richards MJ, Meeker JD, Bastain TM, Breton CV
Environ Health Perspect. 2020 Nov;128(11):117001. doi: 10.1289/EHP7201. Epub 2020 Nov 3.
PMID: 33141601

Prenatal metal mixtures and fetal size in mid-pregnancy in the MADRES study.
Howe CG, Claus Henn B, Farzan SF, Habre R, Eckel SP, Grubbs BH, Chavez TA, Faham D, Al-Marayati L, Lerner D, Quimby A, Twogood S, Richards MJ, Meeker JD, Bastain TM, Breton CV
Environ Res. 2020 Oct 28;:110388. doi: 10.1016/j.envres.2020.110388. Epub 2020 Oct 28.
PMID: 33129852

Prenatal and postnatal mercury exposure and blood pressure in childhood.
Farzan SF, Howe CG, Chen Y, Gilbert-Diamond D, Korrick S, Jackson BP, Weinstein AR, Karagas MR
Environ Int. 2021 Jan;146:106201. doi: 10.1016/j.envint.2020.106201. Epub 2020 Oct 28.
PMID: 33129000

Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
Bozack AK, Howe CG, Hall MN, Liu X, Slavkovich V, Ilievski V, Lomax-Luu AM, Parvez F, Siddique AB, Shahriar H, Uddin MN, Islam T, Graziano JH, Gamble MV
Eur J Nutr. 2020 Sep 11; doi: 10.1007/s00394-020-02377-z. Epub 2020 Sep 11.
PMID: 32918135

Demographic predictors of urinary arsenic in a low-income predominantly Hispanic pregnancy cohort in Los Angeles.
Farzan SF, Howe CG, Chavez TA, Hodes TL, Johnston JE, Habre R, Dunton G, Bastain TM, Breton CV
J Expo Sci Environ Epidemiol. 2021 Feb;31(1):94-107. doi: 10.1038/s41370-020-0251-1. Epub 2020 Jul 27.
PMID: 32719440

Arsenic and birth outcomes in a predominately lower income Hispanic pregnancy cohort in Los Angeles.
Howe CG, Farzan SF, Garcia E, Jursa T, Iyer R, Berhane K, Chavez TA, Hodes TL, Grubbs BH, Funk WE, Smith DR, Bastain TM, Breton CV
Environ Res. 2020 May;184:109294. doi: 10.1016/j.envres.2020.109294. Epub 2020 Feb 27.
PMID: 32145549

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium.
Howe CG, Cox B, Fore R, Jungius J, Kvist T, Lent S, Miles HE, Salas LA, Rifas-Shiman S, Starling AP, Yousefi P, Ladd-Acosta C, Baccarelli A, Binder EB, Chatzi VL, Czamara D, Dabelea D, DeMeo DL, Ghantous A, Herceg Z, Kajantie E, Lahti JMT, Lawlor DA, Litonjua A, Nawrot TS, Nohr EA, Oken E, Pizzi C, Plusquin M, Raikkonen K, Relton CL, Sharp GC, Sorensen TIA, Sunyer J, Vrijheid M, Zhang W, Hivert MF, Breton CV
Diabetes Care. 2020 Jan;43(1):98-105. doi: 10.2337/dc19-0524. Epub 2019 Oct 10.
PMID: 31601636

Associations between Maternal Tobacco Smoke Exposure and the Cord Blood [Formula: see text] DNA Methylome.
Howe CG, Zhou M, Wang X, Pittman GS, Thompson IJ, Campbell MR, Bastain TM, Grubbs BH, Salam MT, Hoyo C, Bell DA, Smith AD, Breton CV
Environ Health Perspect. 2019 Apr;127(4):47009. doi: 10.1289/EHP3398.
PMID: 31039056

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course.
den Dekker HT, Burrows K, Felix JF, Salas LA, Nedeljkovic I, Yao J, Rifas-Shiman SL, Ruiz-Arenas C, Amin N, Bustamante M, DeMeo DL, Henderson AJ, Howe CG, Hivert MF, Ikram MA, de Jongste JC, Lahousse L, Mandaviya PR, van Meurs JB, Pinart M, Sharp GC, Stolk L, Uitterlinden AG, Anto JM, Litonjua AA, Breton CV, Brusselle GG, Sunyer J, Smith GD, Relton CL, Jaddoe VWV, Duijts L
Eur Respir J. 2019 Apr;53(4) pii: 1801795. doi: 10.1183/13993003.01795-2018. Epub 2019 Apr 4.
PMID: 30765504

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