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Caitlin G Howe, PhD

Assistant Professor of Epidemiology

Additional Titles/Positions/Affiliations
Adjunct Research Assistant Professor (University of Southern California)


Columbia University (PhD), 2016
Pomona College (BA), 2009

Quantitative Biomedical Sciences

Academic Analytics
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Contact Information

1 Medical Center Drive
Lebanon NH 03766

Email: Caitlin.G.Howe@Dartmouth.edu

Professional Interests

Dr. Howe’s research focuses on toxic metal exposures and their impacts on maternal and child health, with a particular interest in effects on early life growth and cardiometabolic health. Additional areas of interest include epigenetic mediators of toxicant exposures and metals toxicity in the context of nutritional status and complex environmental mixtures.

Grant Information

Prenatal Metal Mixtures, Fetal Growth, and the Role of MicroRNAs (NIEHS)


Professor Howe received her BA in 2009 from Pomona College, with a major in Biology and a minor in Spanish. After graduating, she worked at Fox Chase Cancer Center in an ovarian cancer research lab. She subsequently pursued a PhD in Environmental Health Sciences at Columbia University's Mailman School of Public Health. After receiving her PhD in 2016, she completed a postdoctoral research fellowship in the Department of Preventive Medicine at the University of Southern California. In 2020, she was appointed to the faculty at the Geisel School of Medicine.

Selected Publications


Urinary fluoride levels and metal co-exposures among pregnant women in Los Angeles, California.
Malin AJ, Hu H, Martinez-Mier EA, Eckel SP, Farzan SF, Howe CG, Funk W, Meeker JD, Habre R, Bastain TM, Breton CV
Environ Health. 2023 Oct 26;22(1):74. doi: 10.1186/s12940-023-01026-2. Epub 2023 Oct 26.
PMID: 37880740

Prenatal exposures to organophosphate ester metabolite mixtures and children's neurobehavioral outcomes in the MADRES pregnancy cohort.
Hernandez-Castro I, Eckel SP, Howe CG, Niu Z, Kannan K, Robinson M, Foley HB, Yang T, Vigil MJ, Chen X, Grubbs B, Lerner D, Lurvey N, Al-Marayati L, Habre R, Dunton GF, Farzan SF, Aung MT, Breton CV, Bastain TM
Environ Health. 2023 Sep 22;22(1):66. doi: 10.1186/s12940-023-01017-3. Epub 2023 Sep 22.
PMID: 37737180

Associations between area-level arsenic exposure and adverse birth outcomes: An Echo-wide cohort analysis.
Lewis JV, Knapp EA, Bakre S, Dickerson AS, Bastain TM, Bendixsen C, Bennett DH, Camargo CA, Cassidy-Bushrow AE, Colicino E, D'Sa V, Dabelea D, Deoni S, Dunlop AL, Elliott AJ, Farzan SF, Ferrara A, Fry RC, Hartert T, Howe CG, Kahn LG, Karagas MR, Ma TF, Koinis-Mitchell D, MacKenzie D, Maldonado LE, Merced-Nieves FM, Neiderhiser JM, Nigra AE, Niu Z, Nozadi SS, Rivera-Nuñez Z, O'Connor TG, Osmundson S, Padula AM, Peterson AK, Sherris AR, Starling A, Straughen JK, Wright RJ, Zhao Q, Kress AM
Environ Res. 2023 Nov 1;236(Pt 2):116772. doi: 10.1016/j.envres.2023.116772. Epub 2023 Jul 28.
PMID: 37517496

A State-of-the-Science Review on Metal Biomarkers.
Martinez-Morata I, Sobel M, Tellez-Plaza M, Navas-Acien A, Howe CG, Sanchez TR
Curr Environ Health Rep. 2023 Sep;10(3):215-249. doi: 10.1007/s40572-023-00402-x. Epub 2023 Jun 20.
PMID: 37337116

Metals and per- and polyfluoroalkyl substances mixtures and birth outcomes in the New Hampshire Birth Cohort Study: Beyond single-class mixture approaches.
Yim G, McGee G, Gallagher L, Baker E, Jackson BP, Calafat AM, Botelho JC, Gilbert-Diamond D, Karagas MR, Romano ME, Howe CG
Chemosphere. 2023 Jul;329:138644. doi: 10.1016/j.chemosphere.2023.138644. Epub 2023 Apr 7.
PMID: 37031836

Sex-specific effects of prenatal organophosphate ester (OPE) metabolite mixtures and adverse infant birth outcomes in the maternal and developmental risks from environmental and social stressors (MADRES) pregnancy cohort.
Hernandez-Castro I, Eckel SP, Howe CG, Niu Z, Kannan K, Robinson M, Foley HB, Grubbs B, Al-Marayati L, Lerner D, Lurvey N, Aung MT, Habre R, Dunton GF, Farzan SF, Breton CV, Bastain TM
Environ Res. 2023 Jun 1;226:115703. doi: 10.1016/j.envres.2023.115703. Epub 2023 Mar 17.
PMID: 36934865

Depression, perceived stress, and distress during pregnancy and EV-associated miRNA profiles in MADRES.
Foley HB, Howe CG, Eckel SP, Chavez T, Gevorkian L, Reyes EG, Kapanke B, Martinez D, Xue S, Suglia SF, Bastain TM, Marsit C, Breton CV
J Affect Disord. 2023 Feb 15;323:799-808. doi: 10.1016/j.jad.2022.12.039. Epub 2022 Dec 20.
PMID: 36563790

Perinatal Metal and Metalloid Exposures and Offspring Cardiovascular Health Risk.
Yim G, Reynaga L, Nunez V, Howe CG, Romano ME, Chen Y, Karagas MR, Toledo-Corral C, Farzan SF
Curr Environ Health Rep. 2022 Dec;9(4):714-734. doi: 10.1007/s40572-022-00377-1. Epub 2022 Aug 18.
PMID: 35980568

Exposure to Metal Mixtures in Association with Cardiovascular Risk Factors and Outcomes: A Scoping Review.
Yim G, Wang Y, Howe CG, Romano ME
Toxics. 2022 Mar 1;10(3) doi: 10.3390/toxics10030116. Epub 2022 Mar 1.
PMID: 35324741

Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies.
Tobi EW, Juvinao-Quintero DL, Ronkainen J, Ott R, Alfano R, Canouil M, Geurtsen ML, Khamis A, Kupers LK, Lim IY, Perron P, Pesce G, Tuhkanen J, Starling AP, Andrew T, Binder E, Caiazzo R, Chan JKY, Gaillard R, Gluckman PD, Keikkala E, Karnani N, Mustaniemi S, Nawrot TS, Pattou F, Plusquin M, Raverdy V, Tan KH, Tzala E, Raikkonen K, Winkler C, Ziegler AG, Annesi-Maesano I, Bouchard L, Chong YS, Dabelea D, Felix JF, Heude B, Jaddoe VWV, Lahti J, Reimann B, Vaarasmaki M, Bonnefond A, Froguel P, Hummel S, Kajantie E, Jarvelin MR, Steegers-Theunissen RPM, Howe CG, Hivert MF, Sebert S
Diabetes Care. 2022 Mar 1;45(3):614-623. doi: 10.2337/dc21-1701.
PMID: 35104326

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