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Caitlin G Howe, PhD

Assistant Professor of Epidemiology

Additional Titles/Positions/Affiliations
Adjunct Research Assistant Professor (University of Southern California)


Columbia University (PhD), 2016
Pomona College (BA), 2009

Quantitative Biomedical Sciences

Contact Information

1 Medical Center Drive
Lebanon NH 03766

Email: Caitlin.G.Howe@Dartmouth.edu

Professional Interests

Dr. Howe’s research focuses on toxic metal exposures and their impacts on maternal and child health, with a particular interest in effects on early life growth and cardiometabolic health. Additional areas of interest include epigenetic mediators of toxicant exposures and metals toxicity in the context of nutritional status and complex environmental mixtures.

Grant Information

Prenatal Metal Mixtures, Fetal Growth, and the Role of MicroRNAs (NIEHS)


Professor Howe received her BA in 2009 from Pomona College, with a major in Biology and a minor in Spanish. After graduating, she worked at Fox Chase Cancer Center in an ovarian cancer research lab. She subsequently pursued a PhD in Environmental Health Sciences at Columbia University's Mailman School of Public Health. After receiving her PhD in 2016, she completed a postdoctoral research fellowship in the Department of Preventive Medicine at the University of Southern California. In 2020, she was appointed to the faculty at the Geisel School of Medicine.

Selected Publications


Depression, perceived stress, and distress during pregnancy and EV-associated miRNA profiles in MADRES.
Foley HB, Howe CG, Eckel SP, Chavez T, Gevorkian L, Reyes EG, Kapanke B, Martinez D, Xue S, Suglia SF, Bastain TM, Marsit C, Breton CV
J Affect Disord. 2023 Feb 15;323:799-808. doi: 10.1016/j.jad.2022.12.039. Epub 2022 Dec 20.
PMID: 36563790

Perinatal Metal and Metalloid Exposures and Offspring Cardiovascular Health Risk.
Yim G, Reynaga L, Nunez V, Howe CG, Romano ME, Chen Y, Karagas MR, Toledo-Corral C, Farzan SF
Curr Environ Health Rep. 2022 Dec;9(4):714-734. doi: 10.1007/s40572-022-00377-1. Epub 2022 Aug 18.
PMID: 35980568

Exposure to Metal Mixtures in Association with Cardiovascular Risk Factors and Outcomes: A Scoping Review.
Yim G, Wang Y, Howe CG, Romano ME
Toxics. 2022 Mar 1;10(3) doi: 10.3390/toxics10030116. Epub 2022 Mar 1.
PMID: 35324741

Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies.
Tobi EW, Juvinao-Quintero DL, Ronkainen J, Ott R, Alfano R, Canouil M, Geurtsen ML, Khamis A, Kupers LK, Lim IY, Perron P, Pesce G, Tuhkanen J, Starling AP, Andrew T, Binder E, Caiazzo R, Chan JKY, Gaillard R, Gluckman PD, Keikkala E, Karnani N, Mustaniemi S, Nawrot TS, Pattou F, Plusquin M, Raverdy V, Tan KH, Tzala E, Raikkonen K, Winkler C, Ziegler AG, Annesi-Maesano I, Bouchard L, Chong YS, Dabelea D, Felix JF, Heude B, Jaddoe VWV, Lahti J, Reimann B, Vaarasmaki M, Bonnefond A, Froguel P, Hummel S, Kajantie E, Jarvelin MR, Steegers-Theunissen RPM, Howe CG, Hivert MF, Sebert S
Diabetes Care. 2022 Mar 1;45(3):614-623. doi: 10.2337/dc21-1701.
PMID: 35104326

Prenatal metal(loid) mixtures and birth weight for gestational age: A pooled analysis of three cohorts participating in the ECHO program.
Howe CG, Nozadi SS, Garcia E, O'Connor TG, Starling AP, Farzan SF, Jackson BP, Madan JC, Alshawabkeh AN, Cordero JF, Bastain TM, Meeker JD, Breton CV, Karagas MR, program collaborators for Environmental Influences on Child Health Outcomes
Environ Int. 2022 Mar;161:107102. doi: 10.1016/j.envint.2022.107102. Epub 2022 Jan 23.
PMID: 35081493

Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort.
Howe CG, Foley HB, Farzan SF, Chavez TA, Johnson M, Meeker JD, Bastain TM, Marsit CJ, Breton CV
Epigenetics. 2022 Oct;17(10):1128-1142. doi: 10.1080/15592294.2021.1994189. Epub 2021 Oct 30.
PMID: 34696694

Extracellular vesicle-enriched miRNA profiles across pregnancy in the MADRES cohort.
Foley HB, Howe CG, Eckel SP, Chavez T, Gevorkian L, Reyes EG, Kapanke B, Martinez D, Xue S, Suglia SF, Bastain TM, Marsit C, Breton CV
PLoS One. 2021;16(5):e0251259. doi: 10.1371/journal.pone.0251259. Epub 2021 May 12.
PMID: 33979365

Exposure to metal mixtures in relation to blood pressure among children 5-7 years old: An observational study in Bangladesh.
Shih YH, Howe CG, Scannell Bryan M, Shahriar M, Kibriya MG, Jasmine F, Sarwar G, Graziano JH, Persky VW, Jackson B, Ahsan H, Farzan SF, Argos M
Environ Epidemiol. 2021 Apr;5(2):e135. doi: 10.1097/EE9.0000000000000135. Epub 2021 Feb 11.
PMID: 33778363

Associations of metals and neurodevelopment: a review of recent evidence on susceptibility factors.
Bauer JA, Fruh V, Howe CG, White RF, Henn BC
Curr Epidemiol Rep. 2020 Dec;7(4):237-262. doi: 10.1007/s40471-020-00249-y. Epub 2020 Oct 30.
PMID: 33777647

Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study.
Howe CG, Foley HB, Kennedy EM, Eckel SP, Chavez TA, Faham D, Grubbs BH, Al-Marayati L, Lerner D, Suglia S, Bastain TM, Marsit CJ, Breton CV
Epigenetics. 2022 Mar;17(3):269-285. doi: 10.1080/15592294.2021.1899887. Epub 2021 Mar 18.
PMID: 33734019

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