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Laura A. Flashman, PhD

Title(s):
Professor of Psychiatry

Department(s):
Psychiatry

Education:
Emory University, PHD 1993
Emory University, MA 1989
Middlebury College, BA 1984

Programs:
Neuroscience Center at Dartmouth
Program in Experimental and Molecular Medicine
Psychopharmacology Research Group

Websites:
http://dms.dartmouth.edu/ncd/
http://synapse.hitchcock.org/

Contact Information:

Geisel School of Medicine
Dept of Psychiatry, HB 7750
Hanover NH 03755

Phone: 603-650-5824
Fax: 603-650-0404
Email: flashman@dartmouth.edu

Assistant: Kelly Leighton


Professional Interests:

Neuropsychology and neuroimaging of schizophrenia and neurological disorders, unawareness of illness, cognition in persons with developmental disabilities, recovery of cognitive and emotional sequelae after Traumatic Brain Injury (TBI).

Rotations and Thesis Projects:

Representative Examples:
The Anatomy of Unawareness in Schizophrenia (thesis)

Adult ADHD and anxiety: Neuropsychological and STAI responses to methylphenidate treatment (dissertation)

Preliminary effects of Dopamine Beta-Hydroxylase single nucleotide polymorphisms on cognitive outcomes after mild traumatic brain injury (PEMM rotation paper with Thomas W. McAllister)

Brain-derived Neurotrophic Factor and its role in cognition one month and one year after traumatic brain injury (PEMM rotation paper with Thomas W. McAllister)

Diffusion Tensor Imaging measures for reliability and longitudinal studies in mild traumatic brain injury (PEMM rotation paper with Thomas W. McAllister)

Grant Information:

Memory Circuitry in Mild Cognitive Impairment and Early Alzheimer's Disease: A Functional and Morphometric MRI Study of Early Detection and Longitudinal Change

Role of Candidate Alleles in Cognitive Outcome After TBI

Effect of Biomechanical Force Exposure on Cognition and Brain Activation in TBI

RCT of Methylphenidate & Memory/Attention Training in TBI

Project RESPONSE: Enhancement of the Capacity of Elderly Adults with Brain Injuries and Families/Caregivers to Self-Manage the Neurobehavioral Consequences

Effect of Biomechanical Force Exposure on Cognition and Brain Activation in Student Athletes

Cognitive Training and Supported Employment for SMI

Role of Alpha-2 Adrenergic Dysregulation in Mild TBI with and without Co-Morbid

PTSD: A Pharmacological Functional MRI Study

Comparison of Acceptance and Commitment Therapy to Present Centered Therapy in Veterans with PTSD with and without TBI

Biography:

Dr. Flashman received her B. A. from Middlebury College in Middlebury, Vermont in 1984 and her Ph.D. in Clinical Psychology from Emory University in Atlanta, GA, in 1993. She completed a postdoctoral fellowship at the Mental Health Clinical Research Center at the University of Iowa Hospitals and Clinics in Iowa City, IA. In 1994, she was appointed assistant professor at the Geisel School of Medicine at Dartmouth. She was board certified in clinical neuropsychology in 2001, and is the Director of the Neuropsychology Programs at DHMC and New Hampshire Hospital. She was promoted to associate professor in 2002 and to professor in 2011.

Mentoring Information:

In addition to PEMM students and Dartmouth undergraduate Presidential Scholars, I have mentored numerous interns and postdoctoral fellows in Clinical Neuropsychology.


Selected Publications:

 

  • McAllister TW, Flashman LA, Maerlender A, Greenwald RM, Beckwith JG, Tosteson TD, Crisco JJ, Brolinson PG, Duma SM, Duhaime AC, Grove MR, Turco JH Cognitive effects of one season of head impacts in a cohort of collegiate contact sport athletes. Neurology. 2012 May;78:1777-84. (view details on MedLine)

  • McAllister TW, Ford JC, Ji S, Beckwith JG, Flashman LA, Paulsen K, Greenwald RM Maximum principal strain and strain rate associated with concussion diagnosis correlates with changes in corpus callosum white matter indices. Ann Biomed Eng 2012 Jan; 40:127-40 (view details on MedLine)

  • Duhaime AC, Beckwith JG, Maerlender AC, McAllister TW, Crisco JJ, Duma SM, Brolinson PG, Rowson S, Flashman LA, Chu JJ, Greenwald RM. Spectrum of acute clinical characteristics of diagnosed concussions in college athletes wearing instrumented helmets: clinical article. J Neurosurg. 2012 Dec;117:1092-9. (view details on MedLine)

  • Magnotta VA, Matsui JT, Liu D, Johnson HJ, Long JD, Bolster BD Jr, Mueller BA, Lim K, Mori S, Helmer KG, Turner JA, Reading S, Lowe MJ, Aylward E, Flashman LA, Bonett G, Paulsen JS. Multicenter reliability of diffusion tensor imaging. Brain Connect. 2012;2:345-55. (view details on MedLine)

  • Risacher SL, Wudunn D, Pepin SM, MaGee TR, McDonald BC, Flashman LA, Wishart HA, Pixley HS, Rabin LA, Paré N, Englert JJ, Schwartz E, Curtain JR, West JD, O'Neill DP, Santulli RB, Newman RW, Saykin AJ. Visual contrast sensitivity in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints. Neurobiol Aging. 2013 Apr;34:1133-44. (view details on MedLine)

  • Bujarski KA, Hirashima F, Roberts DW, Jobst BC, Gilbert KL, Roth RM, Flashman LA, McDonald BC, Saykin AJ, Scott RC, Dinnerstein E, Preston J, Williamson PD, Thadani VM. Long-term seizure, cognitive, and psychiatric outcome following trans-middle temporal gyrus amygdalohippocampectomy and standard temporal lobectomy. J Neurosurg. 2013 Jul;119:16-23. (view details on MedLine)

  • Risacher SL, Wang Y, Wishart HA, Rabin LA, Flashman LA, McDonald BC, West JD, Santulli RB, Saykin AJ. Cholinergic Enhancement of Brain Activation in Mild Cognitive Impairment during Episodic Memory Encoding. Front Psychiatry. 2013 Sep 17;4:105. (view details on MedLine)

  • Maerlender AC, Flashman LA, Kessler A, Kumbhani S, Greenwald R, Tosteson T, McAllister TW. The discriminant construct validity of ImPACT™: A companion study. The Clinical Neuropsychologist, 27(2), 290-299. 2013

  • Ji S, Ghadyani H, Bolander RP, Beckwith JG, Ford JC, McAllister TW, Flashman LA, Paulsen KD, Ernstrom K, Jain S, Raman R, Zhang L, Greenwald RM. Parametric comparisons of intracranial mechanical responses from three validated finite element models of the human head. Ann Biomed Eng. 2014 Jan;42:11-24. (view details on MedLine)

  • McAllister TW, Ford JC, Flashman LA, Maerlender A, Greenwald RM, Beckwith JG, Bolander RP, Tosteson TD, Turco JH, Raman R, Jain S. Effect of head impacts on diffusivity measures in a cohort of collegiate contact sport athletes. Neurology. 2014 Jan 7;82:63-9. (view details on MedLine)