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Bonnie W Lau, MD, PhD

Title(s):
Assistant Professor of Pediatrics

Additional Titles/Positions/Affiliations:
Pediatric Hematologist Oncologist
Norris Cotton Cancer Center (Principal Investigator)

Department(s):
Pediatrics

Programs:
Program in Experimental and Molecular Medicine

Websites:
https://graduate.dartmouth.edu/mcb/people/faculty/cancer-biology-canb-faculty

https://www.dartmouth-hitchcock.org/findaprovider/provider/2961

https://cancer.dartmouth.edu/pediatric

Contact Information:

One Medical Center Drive
Lebanon NH 03756

Office: 603-650-6475
Phone: 603-653-9964
Fax: 603-650-0591
Email: Bonnie.W.Lau@Dartmouth.edu


Selected Publications:

 

  • Kennedy AL, Myers KC, Bowman J, Gibson CJ, Camarda ND, Furutani E, Muscato GM, Klein RH, Ballotti K, Liu S, Harris CE, Galvin A, Malsch M, Dale D, Gansner JM, Nakano TA, Bertuch A, Vlachos A, Lipton JM, Castillo P, Connelly J, Churpek J, Edwards JR, Hijiy Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. Nat Commun. 2021 Feb 26;12(1):1334 (view details in PubMed)

  • Nakano TA, Lau BW, Dickerson KE, Wlodarski M, Pollard J, Shimamura A, Hofmann I, Sasa G, Elghetany T, Cada M, Dror Y, Ding H, Allen SW, Hanna R, Campbell K, Olson TS Diagnosis and treatment of pediatric myelodysplastic syndromes: A survey of the North American Pediatric Aplastic Anemia Consortium. Pediatr Blood Cancer. 2020 Oct;67(10):e28652 (view details in PubMed)

  • Berk J, Hall D, Stroh I, Armstrong C, Mishra K, Pecker LH, Lau BW A Child With Pancytopenia and Optic Disc Swelling. Pediatrics. 2019 Nov;144(5) (view details in PubMed)

  • Lau BW, Huh K, Madero-Marroquin R, De Marchi F, Lim Y, Wang Q, Lobo F, Marchionni L, Smith DB, DeZern A, Levis MJ, Aplan PD, Matsui W, Gondek LP Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity. Oncogene. 2019 Jan;38(5):687-698 (view details in PubMed)

  • Candoni A, De Marchi F, Zannier ME, Lazzarotto D, Filì C, Dubbini MV, Rabassi N, Toffoletti E, Lau BW, Fanin R High prognostic value of pre-allogeneic stem cell transplantation minimal residual disease detection by WT1 gene expression in AML transplanted in cytologic complete remission. Leuk Res. 2017 Dec;63:22-27 (view details in PubMed)

  • De Marchi F, Candoni A, Zannier ME, Haley L, Lau BW, Fanin R Concomitant monitoring of WT1 and FLT3-ITD expression in FLT3-ITD acute myeloid leukemia patients: which should we trust as a minimal residual disease marker? Am J Hematol. 2017 May;92(5):E72-E74 (view details in PubMed)

  • Lau B, Khazanie U, Rowe E, Fauman K. How a Drug Shortage Contributed to a Medication Error Leading to Baclofen Toxicity in an Infant. J Pediatr Pharmacol Ther. 2016 Nov-Dec;21(6):527-529 (view details in PubMed)

  • Miselis NR, Lau BW, Wu Z, Kane AB Kinetics of host cell recruitment during dissemination of diffuse malignant peritoneal mesothelioma. Cancer Microenviron. 2010 Jun 22;4(1):39-50 (view details in PubMed)

  • Lau BW, Kane AB SDF1/CXCL12 is involved in recruitment of stem-like progenitor cells to orthotopic murine malignant mesothelioma spheroids. Anticancer Res. 2010 Jun;30(6):2153-60 (view details in PubMed)

  • Leong HX, Simkevich C, Lesieur-Brooks A, Lau BW, Fugere C, Sabo E, Thompson NL Short-term arginine deprivation results in large-scale modulation of hepatic gene expression in both normal and tumor cells: microarray bioinformatic analysis. Nutr Metab (Lond). 2006 Sep 8;3:37 (view details in PubMed)