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Bonnie W Lau, MD, PhD

Title(s):
Assistant Professor of Pediatrics

Additional Titles/Positions/Affiliations:
Pediatric Hematologist Oncologist
Norris Cotton Cancer Center (Principal Investigator)

Department(s):
Pediatrics

Programs:
Program in Experimental and Molecular Medicine

Websites:
https://graduate.dartmouth.edu/pemm/pemm-research/cancer-biology-pharmacology-and-molecular-therapeutics-laboratories

https://www.dartmouth-hitchcock.org/findaprovider/provider/2961

https://www.chadkids.org/hematology-oncology.html

Contact Information:

One Medical Center Drive
Lebanon NH 03756

Office: 603-650-6475
Phone: 603-653-9964
Fax: 603-650-0591
Email: Bonnie.W.Lau@Dartmouth.edu


Selected Publications:

 

  • Berk J, Hall D, Stroh I, Armstrong C, Mishra K, Pecker LH, Lau BW A Child With Pancytopenia and Optic Disc Swelling. Pediatrics. 2019 Nov;144(5) (view details on MedLine)

  • Lau BW, Huh K, Madero-Marroquin R, De Marchi F, Lim Y, Wang Q, Lobo F, Marchionni L, Smith DB, DeZern A, Levis MJ, Aplan PD, Matsui W, Gondek LP Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity. Oncogene. 2019 Jan;38(5):687-698

  • Candoni A, De Marchi F, Zannier ME, Lazzarotto D, Filì C, Dubbini MV, Rabassi N, Toffoletti E, Lau BW, Fanin R High prognostic value of pre-allogeneic stem cell transplantation minimal residual disease detection by WT1 gene expression in AML transplanted in cytologic complete remission. Leuk Res. 2017 Dec;63:22-27 (view details on MedLine)

  • De Marchi F, Candoni A, Zannier ME, Haley L, Lau BW, Fanin R Concomitant monitoring of WT1 and FLT3-ITD expression in FLT3-ITD acute myeloid leukemia patients: which should we trust as a minimal residual disease marker? Am J Hematol. 2017 May;92(5):E72-E74 (view details on MedLine)

  • Lau B, Khazanie U, Rowe E, Fauman K. How a Drug Shortage Contributed to a Medication Error Leading to Baclofen Toxicity in an Infant. J Pediatr Pharmacol Ther. 2016 Nov-Dec;21(6):527-529

  • Miselis NR, Lau BW, Wu Z, Kane AB Kinetics of host cell recruitment during dissemination of diffuse malignant peritoneal mesothelioma. Cancer Microenviron. 2010 Jun 22;4(1):39-50

  • Lau BW, Kane AB SDF1/CXCL12 is involved in recruitment of stem-like progenitor cells to orthotopic murine malignant mesothelioma spheroids. Anticancer Res. 2010 Jun;30(6):2153-60 (view details on MedLine)

  • Leong HX, Simkevich C, Lesieur-Brooks A, Lau BW, Fugere C, Sabo E, Thompson NL Short-term arginine deprivation results in large-scale modulation of hepatic gene expression in both normal and tumor cells: microarray bioinformatic analysis. Nutr Metab (Lond). 2006 Sep 8;3:37 (view details on MedLine)

  • Lau BW, Colella M, Ruder WC, Ranieri M, Curci S, Hofer AM Deoxycholic acid activates protein kinase C and phospholipase C via increased Ca2+ entry at plasma membrane. Gastroenterology. 2005 Mar;128(3):695-707 (view details on MedLine)

  • Gerbino A, Hofer AM, McKay B, Lau BW, Soybel DI Divalent cations regulate acidity within the lumen and tubulovesicle compartment of gastric parietal cells. Gastroenterology. 2004 Jan;126(1):182-95 (view details on MedLine)