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Louis J Vaickus, MD, PhD

Title(s)
Associate Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations
Medical Director of Pathology Informatics

Department(s)
Pathology and Laboratory Medicine

Education
BA, Hamilton College, Clinton NY, 2001-2005
MD, Boston University School of Medicine, Boston MA, 2005-2012
PhD, Boston University School of Medicine, Boston MA, 2005-2012
Anatomic Pathology Residency, Massachusetts General Hospital, Boston MA, 2012-2016
Cytopathology Fellowship, Massachusetts General Hospital, Boston MA, 2014-2015

Contact Information

1 Medical Center Drive
Lebanon NH 03766

Office: Borwell 4
Phone: 53844
Email: Louis.J.Vaickus@Dartmouth.edu

Professional Interests

Informatics
Deep learning
Medical image analysis
Automation
Programming

Grant Information

SYNERGY Clinical Research Fellow, 2018-2019

Selected Publications
 

Seven-year retrospective review of medical microbiologist consultations on cytology specimens at an academic medical center.
Marotti JD, Gutmann EJ, Loeven NA, Liu X, Kerr DA, Vaickus LJ, Martin IW
Am J Clin Pathol. 2025 Sep 25; pii: aqaf100. doi: 10.1093/ajcp/aqaf100. Epub 2025 Sep 25.
PMID: 40994162

Association of deep learning-derived histologic features of placental chorionic villi with maternal and infant characteristics in the New Hampshire birth cohort study.
Anderson EC, Srinivasan G, Howe CG, Zhang E, Jeon C, Gupta Paruchuri GS, Zhang L, Hwang L, Sengar A, Reddy N, Karan A, Chen A, Shen J, Owo O, Caraballo-Bobea Z, Khatchikian C, Palys TJ, Vaickus LJ, Yao K, Medeiros F, Nguyen H, Madan JC, Karagas MR, Bentz JL, Levy JJ
Placenta. 2025 Oct;170:87-96. doi: 10.1016/j.placenta.2025.07.084. Epub 2025 Jul 23.
PMID: 40902262

Association of Deep Learning-Derived Histologic Features of Placental Chorionic Villi with Maternal and Infant Characteristics in the New Hampshire Birth Cohort Study.
Anderson EC, Srinivasan G, Howe CG, Zhang E, Jeon C, Paruchuri GSG, Zhang L, Hwang L, Sengar A, Reddy N, Karan A, Chen A, Shen J, Owo O, Caraballo-Bobea Z, Khatchikian C, Palys TJ, Vaickus LJ, Madan JC, Karagas MR, Bentz JL, Levy JJ
medRxiv. 2025 Apr 23; pii: 2025.04.22.25325465. doi: 10.1101/2025.04.22.25325465. Epub 2025 Apr 23.
PMID: 40313259

An initial game-theoretic assessment of enhanced tissue preparation and imaging protocols for improved deep learning inference of spatial transcriptomics from tissue morphology.
Fatemi MY, Lu Y, Diallo AB, Srinivasan G, Azher ZL, Christensen BC, Salas LA, Tsongalis GJ, Palisoul SM, Perreard L, Kolling FW 4th, Vaickus LJ, Levy JJ
Brief Bioinform. 2024 Sep 23;25(6) doi: 10.1093/bib/bbae476.
PMID: 39367648

Artificial Intelligence Applications in Cytopathology: Current State of the Art.
Vaickus LJ, Kerr DA, Velez Torres JM, Levy J
Surg Pathol Clin. 2024 Sep;17(3):521-531. doi: 10.1016/j.path.2024.04.011. Epub 2024 May 30.
PMID: 39129146

Thyroid Fine-Needle Aspiration: The Current and Future Landscape of Cytopathology.
Velez Torres JM, Vaickus LJ, Kerr DA
Surg Pathol Clin. 2024 Sep;17(3):371-381. doi: 10.1016/j.path.2024.04.005. Epub 2024 May 19.
PMID: 39129137

Intraoperative margin assessment for basal cell carcinoma with deep learning and histologic tumor mapping to surgical site.
Levy JJ, Davis MJ, Chacko RS, Davis MJ, Fu LJ, Goel T, Pamal A, Nafi I, Angirekula A, Suvarna A, Vempati R, Christensen BC, Hayden MS, Vaickus LJ, LeBoeuf MR
NPJ Precis Oncol. 2024 Jan 3;8(1):2. doi: 10.1038/s41698-023-00477-7. Epub 2024 Jan 3.
PMID: 38172524

Correction: A2B Adenosine Receptor Expression by Myeloid Cells is Proinflammatory in Murine Allergic-Airway Inflammation.
Belikoff BG, Vaickus LJ, Sitkovsky M, Remick DG
J Immunol. 2024 Feb 15;212(4):748. doi: 10.4049/jimmunol.2300855.
PMID: 38169328

Potential to Enhance Large Scale Molecular Assessments of Skin Photoaging through Virtual Inference of Spatial Transcriptomics from Routine Staining.
Srinivasan G, Davis MJ, LeBoeuf MR, Fatemi M, Azher ZL, Lu Y, Diallo AB, Saldias Montivero MK, Kolling FW, Perrard L, Salas LA, Christensen BC, Palys TJ, Karagas MR, Palisoul SM, Tsongalis GJ, Vaickus LJ, Preum SM, Levy JJ
Pac Symp Biocomput. 2024;29:477-491.
PMID: 38160301

Spatial Omics Driven Crossmodal Pretraining Applied to Graph-based Deep Learning for Cancer Pathology Analysis.
Azher ZL, Fatemi M, Lu Y, Srinivasan G, Diallo AB, Christensen BC, Salas LA, Kolling FW, Perreard L, Palisoul SM, Vaickus LJ, Levy JJ
Pac Symp Biocomput. 2024;29:464-476.
PMID: 38160300

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