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Louis J Vaickus, MD, PhD

Associate Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations
Medical Director of Pathology Informatics

Pathology and Laboratory Medicine

BA, Hamilton College, Clinton NY, 2001-2005
MD, Boston University School of Medicine, Boston MA, 2005-2012
PhD, Boston University School of Medicine, Boston MA, 2005-2012
Anatomic Pathology Residency, Massachusetts General Hospital, Boston MA, 2012-2016
Cytopathology Fellowship, Massachusetts General Hospital, Boston MA, 2014-2015

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Contact Information

1 Medical Center Drive
Lebanon NH 03766

Office: Borwell 4
Phone: 53844
Email: Louis.J.Vaickus@Dartmouth.edu

Professional Interests

Deep learning
Medical image analysis

Grant Information

SYNERGY Clinical Research Fellow, 2018-2019

Selected Publications


Intraoperative margin assessment for basal cell carcinoma with deep learning and histologic tumor mapping to surgical site.
Levy JJ, Davis MJ, Chacko RS, Davis MJ, Fu LJ, Goel T, Pamal A, Nafi I, Angirekula A, Suvarna A, Vempati R, Christensen BC, Hayden MS, Vaickus LJ, LeBoeuf MR
NPJ Precis Oncol. 2024 Jan 3;8(1):2. doi: 10.1038/s41698-023-00477-7. Epub 2024 Jan 3.
PMID: 38172524

Correction: A2B Adenosine Receptor Expression by Myeloid Cells is Proinflammatory in Murine Allergic-Airway Inflammation.
Belikoff BG, Vaickus LJ, Sitkovsky M, Remick DG
J Immunol. 2024 Feb 15;212(4):748. doi: 10.4049/jimmunol.2300855.
PMID: 38169328

Potential to Enhance Large Scale Molecular Assessments of Skin Photoaging through Virtual Inference of Spatial Transcriptomics from Routine Staining.
Srinivasan G, Davis MJ, LeBoeuf MR, Fatemi M, Azher ZL, Lu Y, Diallo AB, Saldias Montivero MK, Kolling FW, Perrard L, Salas LA, Christensen BC, Palys TJ, Karagas MR, Palisoul SM, Tsongalis GJ, Vaickus LJ, Preum SM, Levy JJ
Pac Symp Biocomput. 2024;29:477-491.
PMID: 38160301

Spatial Omics Driven Crossmodal Pretraining Applied to Graph-based Deep Learning for Cancer Pathology Analysis.
Azher ZL, Fatemi M, Lu Y, Srinivasan G, Diallo AB, Christensen BC, Salas LA, Kolling FW, Perreard L, Palisoul SM, Vaickus LJ, Levy JJ
Pac Symp Biocomput. 2024;29:464-476.
PMID: 38160300

The Overlooked Role of Specimen Preparation in Bolstering Deep Learning-Enhanced Spatial Transcriptomics Workflows.
Fatemi MY, Lu Y, Diallo AB, Srinivasan G, Azher ZL, Christensen BC, Salas LA, Tsongalis GJ, Palisoul SM, Perreard L, Kolling FW, Vaickus LJ, Levy JJ
medRxiv. 2023 Oct 9; pii: 2023.10.09.23296700. doi: 10.1101/2023.10.09.23296700. Epub 2023 Oct 9.
PMID: 37873287

Feasibility of Inferring Spatial Transcriptomics from Single-Cell Histological Patterns for Studying Colon Cancer Tumor Heterogeneity.
Fatemi MY, Lu Y, Sharma C, Feng E, Azher ZL, Diallo AB, Srinivasan G, Rosner GM, Pointer KB, Christensen BC, Salas LA, Tsongalis GJ, Palisoul SM, Perreard L, Kolling FW, Vaickus LJ, Levy JJ
medRxiv. 2023 Oct 9; pii: 2023.10.09.23296701. doi: 10.1101/2023.10.09.23296701. Epub 2023 Oct 9.
PMID: 37873186

A deep learning algorithm to detect cutaneous squamous cell carcinoma on frozen sections in Mohs micrographic surgery: A retrospective assessment.
Davis MJ, Srinivasan G, Chacko R, Chen S, Suvarna A, Vaickus LJ, Torres VC, Hodge S, Chen EY, Preum S, Samkoe KS, Christensen BC, LeBoeuf MR, Levy JJ
Exp Dermatol. 2024 Jan;33(1):e14949. doi: 10.1111/exd.14949. Epub 2023 Oct 21.
PMID: 37864429

Use of molecular testing results to analyze the overuse of atypia of undetermined significance in thyroid cytology.
Martinez Coconubo D, Levy JJ, Kerr DA, Vaickus LJ, Vidis L, Glass RE, Gutmann EJ, Marotti JD, Liu X
J Am Soc Cytopathol. 2023 Nov-Dec;12(6):451-460. doi: 10.1016/j.jasc.2023.09.002. Epub 2023 Sep 7.
PMID: 37775434

Assessment of emerging pretraining strategies in interpretable multimodal deep learning for cancer prognostication.
Azher ZL, Suvarna A, Chen JQ, Zhang Z, Christensen BC, Salas LA, Vaickus LJ, Levy JJ
BioData Min. 2023 Jul 22;16(1):23. doi: 10.1186/s13040-023-00338-w. Epub 2023 Jul 22.
PMID: 37481666

Paired-agent imaging as a rapid en face margin screening method in Mohs micrographic surgery.
Torres VC, Hodge S, Levy JJ, Vaickus LJ, Chen EY, LeBouef M, Samkoe KS
Front Oncol. 2023;13:1196517. doi: 10.3389/fonc.2023.1196517. Epub 2023 Jun 22.
PMID: 37427140

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