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Rahul Sarpeshkar, PhD

Title(s):
Professor of Microbiology and Immunology
Professor of Molecular and Systems Biology

Additional Titles/Positions/Affiliations:
Thomas E. Kurtz Professor
Professor of Engineering
Professor of Physics

Department(s):
Microbiology and Immunology
Molecular and Systems Biology

Education:
BS, Electrical Engineering and Physics, MIT
PhD, Computation and Neural Systems, California Institute of Technology

Programs:
Molecular and Cellular Biology Graduate Programs

Websites:
Thayer Profile:
http://engineering.dartmouth.edu/people/faculty/rahul-sarpeshkar/

TEDx Talk:
https://www.youtube.com/watch?v=ZycidN_GYo0

Contact Information:


Professional Interests:

Synthetic analog and digital biological circuits in electri-cigenic and other microbes. Applications of synthetic and systems biology to immunology, infectious disease, and cancer.

Biography:

Awards
NSF CAREER Award
ONR Young Investigator Award
Packard Fellow Award
Junior Bose Teaching Award, MIT
Fellow, National Academy of Inventors
Fellow, IEEE


Selected Publications:

 

A Novel Bioelectronic Reporter System in Living Cells Tested with a Synthetic Biological Comparator.
Zeng J, Banerjee A, Kim J, Deng Y, Chapman TW, Daniel R, Sarpeshkar R
Sci Rep. 2019 May 13;9(1):7275. doi: 10.1038/s41598-019-43771-w. Epub 2019 May 13.
PMID: 31086248

An Artificial Tissue Homeostasis Circuit Designed via Analog Circuit Techniques.
Teo JJY, Weiss R, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2019 Jun;13(3):540-553. doi: 10.1109/TBCAS.2019.2907074. Epub 2019 Mar 25.
PMID: 30908238

A Synthetic Microbial Operational Amplifier.
Zeng J, Teo J, Banerjee A, Chapman TW, Kim J, Sarpeshkar R
ACS Synth Biol. 2018 Sep 21;7(9):2007-2013. doi: 10.1021/acssynbio.8b00138. Epub 2018 Aug 30.
PMID: 30152993

Fast and Precise Emulation of Stochastic Biochemical Reaction Networks With Amplified Thermal Noise in Silicon Chips.
Kim J, Woo SS, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2018 Apr;12(2):379-389. doi: 10.1109/TBCAS.2017.2786306.
PMID: 29570064

A Digitally Programmable Cytomorphic Chip for Simulation of Arbitrary Biochemical Reaction Networks.
Woo SS, Kim J, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2018 Apr;12(2):360-378. doi: 10.1109/TBCAS.2017.2781253.
PMID: 29570063

Bioelectronic measurement and feedback control of molecules in living cells.
Banerjee A, Weaver I, Thorsen T, Sarpeshkar R
Sci Rep. 2017 Oct 2;7(1):12511. doi: 10.1038/s41598-017-12655-2. Epub 2017 Oct 2.
PMID: 28970494

Guest Editorial - Special Issue on Synthetic Biology.
Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2015 Aug;9(4):449-52.
PMID: 26839930

Synthetic Biology: A Unifying View and Review Using Analog Circuits.
Teo JJ, Woo SS, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2015 Aug;9(4):453-74. Epub 2015 Sep 11.
PMID: 26372648

Analog synthetic biology.
Sarpeshkar R
Philos Trans A Math Phys Eng Sci. 2014 Mar 28;372(2012):20130110. doi: 10.1098/rsta.2013.0110. Epub 2014 Feb 24.
PMID: 24567476

Synthetic analog computation in living cells.
Daniel R, Rubens JR, Sarpeshkar R, Lu TK
Nature. 2013 May 30;497(7451):619-23. doi: 10.1038/nature12148. Epub 2013 May 15.
PMID: 23676681

View more publications on PubMed