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Margaret Rita Karagas, PhD

Chair and Professor of Epidemiology
Professor of Community and Family Medicine
James W. Squires Professor

Additional Titles/Positions/Affiliations:
Director, Children's Environmental Health and Disease Prevention Research Center and Center for Molecular Epidemiology

Community and Family Medicine

University of Washington, PhD 1990

Norris Cotton Cancer Center
Quantitative Biomedical Sciences


Contact Information:

Department of Epidemiology
1 Medical Center Drive
7927 Rubin Building
Lebanon NH 03756

Office: 863 Rubin Bldg Lebanon, NH
Phone: 603-653-9010
Fax: 603-653-9093

Assistant: Evan Vickers
Asst. Phone: 603-650-1918
Asst. Email:

Professional Interests:

Professor Karagas' research encompasses several epidemiological studies focusing on the etiology and prevention of human cancers over the lifecourse, as well as adverse pregnancy and children's health outcomes. These include investigations to determine incidence rates of basal cell and squamous cell skin cancer for a geographically defined US population, and to assess the extent of any increase over the past 20 years. Another aspect of this research is a case-control study of these malignancies to identify risks associated with emerging exposures such as indoor tanning, ingestion of arsenic-containing drinking water and foods, immunosuppressive therapies and other factors. This research has been extended to bladder cancer. One of her current initiatives involves establishing a cohort of pregnant women in New Hampshire to assess the potential impact of arsenic and other exposures on risk of maternal and child health. Her ongoing work further includes studies of melanoma in women and collaborative investigations of exposure biomarkers, individual susceptibility, and biological response to environmental agents. Professor Karagas is one of the Principal Investigators of a NCI-funded cross-disciplinary postdoctoral training grant, serves as a mentor for early career investigators and participates in a variety of courses at the undergraduate and graduate level.

Selected Publications:


Prospective associations of the infant gut microbiome and microbial function with social behaviors related to autism at age 3 years.
Laue HE, Korrick SA, Baker ER, Karagas MR, Madan JC
Sci Rep. 2020 Sep 23;10(1):15515. doi: 10.1038/s41598-020-72386-9. Epub 2020 Sep 23.
PMID: 32968156

Distributional Properties and Criterion Validity of a Shortened Version of the Social Responsiveness Scale: Results from the ECHO Program and Implications for Social Communication Research.
Lyall K, Hosseini M, Ladd-Acosta C, Ning X, Catellier D, Constantino JN, Croen LA, Kaat AJ, Botteron K, Bush NR, Dager SR, Duarte CS, Fallin MD, Hazlett H, Hertz-Picciotto I, Joseph RM, Karagas MR, Korrick S, Landa R, Messinger D, Oken E, Ozonoff S, Piven J, Pandey J, Sathyanarayana S, Schultz RT, St John T, Schmidt R, Volk H, Newschaffer CJ, program collaborators for Environmental influences on Child Health Outcomes.
J Autism Dev Disord. 2020 Sep 17; doi: 10.1007/s10803-020-04667-1. Epub 2020 Sep 17.
PMID: 32944847

Toenail metal concentrations and age at menopause: A prospective study.
White AJ, O'Brien KM, Niehoff NM, Jackson BP, Karagas MR, Weinberg CR, Keil AP
Environ Epidemiol. 2020 Aug;4(4):e0104. doi: 10.1097/EE9.0000000000000104. Epub 2020 Jul 16.
PMID: 32832842

Maternal cadmium exposure and neurobehavior in children: The HOME study.
Yang W, Vuong AM, Xie C, Dietrich KN, Karagas MR, Lanphear BP, Braun JM, Yolton K, Chen A
Environ Res. 2020 Jul;186:109583. doi: 10.1016/j.envres.2020.109583. Epub 2020 Apr 25.
PMID: 32668545

Identification of let-7f-5p as a novel biomarker of recurrence in non-muscle invasive bladder cancer.
Shee K, Seigne JD, Karagas MR, Marsit CJ, Hinds JW, Schned AR, Pettus JR, Armstrong DA, Miller TW, Andrew AS
Cancer Biomark. 2020 Jun 28; doi: 10.3233/CBM-191322. Epub 2020 Jun 28.
PMID: 32623385

A Machine Learning Approach for Long-Term Prognosis of Bladder Cancer based on Clinical and Molecular Features.
Song Q, Seigne JD, Schned AR, Kelsey KT, Karagas MR, Hassanpour S
AMIA Jt Summits Transl Sci Proc. 2020;2020:607-616. Epub 2020 May 30.
PMID: 32477683

Assessment of Maternal Glycemia and Newborn Size Among Pregnant Women Who Use Wood Stoves in Northern New England.
Fleisch AF, Seshasayee SM, Garshick E, Chipman JW, Koutrakis P, Baker ER, Karagas MR
JAMA Netw Open. 2020 May 1;3(5):e206046. doi: 10.1001/jamanetworkopen.2020.6046. Epub 2020 May 1.
PMID: 32463466

The Authors Respond.
Karagas MR, Barton D, Zens MS, Gilbert-Diamond D, Marmarelis EL
Epidemiology. 2020 Sep;31(5):e39-e40. doi: 10.1097/EDE.0000000000001205.
PMID: 32366753

A data mining approach to investigate food groups related to incidence of bladder cancer in the BLadder cancer Epidemiology and Nutritional Determinants International Study.
Yu EYW, Wesselius A, Sinhart C, Wolk A, Stern MC, Jiang X, Tang L, Marshall J, Kellen E, van den Brandt P, Lu CM, Pohlabeln H, Steineck G, Allam MF, Karagas MR, La Vecchia C, Porru S, Carta A, Golka K, Johnson KC, Benhamou S, Zhang ZF, Bosetti C, Taylor JA, Weiderpass E, Grant EJ, White E, Polesel J, Zeegers MPA
Br J Nutr. 2020 Sep 28;124(6):611-619. doi: 10.1017/S0007114520001439. Epub 2020 Apr 23.
PMID: 32321598

Risk of melanoma following keratinocyte malignancies.
Robinson SN, Zens MS, Rees JR, Barton DT, Karagas MR
Int J Cancer. 2020 Oct 15;147(8):2116-2120. doi: 10.1002/ijc.33011. Epub 2020 Apr 30.
PMID: 32285932

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