Edit Entry

Margaret Rita Karagas, PhD

Title(s):
Chair and Professor of Epidemiology
Professor of Community and Family Medicine

Additional Titles/Positions/Affiliations:
Director, Children's Environmental Health and Disease Prevention Research Center and Center for Molecular Epidemiology

Department(s):
Epidemiology
Community and Family Medicine

Education:
University of Washington, PhD 1990

Programs:
Norris Cotton Cancer Center
Quantitative Biomedical Sciences

Websites:
http://epidemiology.dartmouth.edu/faculty/karagasm.html
http://www.dartmouth.edu/~childrenshealth/
http://sites.dartmouth.edu/molecepi/
http://cancer.dartmouth.edu/res/cancer_epi_chemo.html
http://www.dartmouth.edu/~toxmetal/index.html
http://synergy.dartmouth.edu
http://iqbs.org

Contact Information:

Department of Epidemiology
1 Medical Center Drive
7927 Rubin Building
Lebanon NH 03756

Office: 863 Rubin Bldg Lebanon, NH
Phone: 603-653-9010
Fax: 603-653-9093
Email: Margaret.Karagas@dartmouth.edu

Assistant: Kara Caputo
Asst. Phone: 603-653-9022
Asst. Email: Kara.L.Caputo@dartmouth.edu


Professional Interests:

Professor Karagas' research encompasses several epidemiological studies focusing on the etiology and prevention of human cancers, as well as adverse pregnancy and children's health outcomes. These include investigations to determine incidence rates of basal cell and squamous cell skin cancer for a geographically defined US population, and to assess the extent of any increase over the past 20 years. Another aspect of this research is a case-control study of these malignancies to identify risks associated with emerging exposures such as indoor tanning, ingestion of arsenic-containing drinking water and foods, immunosuppressive therapies and other factors. This research has been extended to bladder cancer. One of her current initiatives involves establishing a cohort of pregnant women in New Hampshire to assess the potential impact of arsenic and other exposures on risk of maternal and child health. Her ongoing work further includes studies of melanoma in women and collaborative investigations of exposure biomarkers, individual susceptibility, and biological response to environmental agents. Professor Karagas is one of the Principal Investigators of a NCI-funded cross-disciplinary postdoctoral training grant, serves as a mentor for early career investigators and participates in a variety of courses at the undergraduate and graduate level.


Selected Publications:

 

Do post-breast cancer diagnosis toenail trace element concentrations reflect pre-diagnostic concentrations?
O'Brien KM, White AJ, Sandler DP, Jackson BP, Karagas MR, Weinberg CR
Epidemiology. 2018 Sep 25; doi: 10.1097/EDE.0000000000000927. Epub 2018 Sep 25.
PMID: 30256233

Opportunities and Challenges for Dietary Arsenic Intervention.
Nachman KE, Punshon T, Rardin L, Signes-Pastor AJ, Murray CJ, Jackson BP, Guerinot ML, Burke TA, Chen CY, Ahsan H, Argos M, Cottingham KL, Cubadda F, Ginsberg GL, Goodale BC, Kurzius-Spencer M, Meharg AA, Miller MD, Nigra AE, Pendergrast CB, Raab A, Reimer K, Scheckel KG, Schwerdtle T, Taylor VF, Tokar EJ, Warczak TM, Karagas MR
Environ Health Perspect. 2018 Aug;126(8):84503. doi: 10.1289/EHP3997.
PMID: 30235424

Impact of receipt of private well arsenic test results on maternal use of contaminated drinking water in a U.S. population.
He X, Karagas MR, Murray C
Sci Total Environ. 2018 Dec 1;643:1005-1012. doi: 10.1016/j.scitotenv.2018.06.228. Epub 2018 Jun 28.
PMID: 30189517

Sex-specific associations of infants' gut microbiome with arsenic exposure in a US population.
Hoen AG, Madan JC, Li Z, Coker M, Lundgren SN, Morrison HG, Palys T, Jackson BP, Sogin ML, Cottingham KL, Karagas MR
Sci Rep. 2018 Aug 22;8(1):12627. doi: 10.1038/s41598-018-30581-9. Epub 2018 Aug 22.
PMID: 30135504

Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network.
Deyssenroth MA, Gennings C, Liu SH, Peng S, Hao K, Lambertini L, Jackson BP, Karagas MR, Marsit CJ, Chen J
Environ Int. 2018 Nov;120:373-381. doi: 10.1016/j.envint.2018.08.010. Epub 2018 Aug 17.
PMID: 30125854

Profiles and Predictors of Environmental Chemical Mixture Exposure among Pregnant Women: The Health Outcomes and Measures of the Environment Study.
Kalloo G, Wellenius GA, McCandless L, Calafat AM, Sjodin A, Karagas M, Chen A, Yolton K, Lanphear BP, Braun JM
Environ Sci Technol. 2018 Sep 4;52(17):10104-10113. doi: 10.1021/acs.est.8b02946. Epub 2018 Aug 21.
PMID: 30088764

Potential effect modifiers of the arsenic-bladder cancer risk relationship.
Koutros S, Baris D, Waddell R, Beane Freeman LE, Colt JS, Schwenn M, Johnson A, Ward MH, Hosain GM, Moore LE, Stolzenberg-Solomon R, Rothman N, Karagas MR, Silverman DT
Int J Cancer. 2018 Jul 7; doi: 10.1002/ijc.31720. Epub 2018 Jul 7.
PMID: 29981168

Maternal diet during pregnancy is related with the infant stool microbiome in a delivery mode-dependent manner.
Lundgren SN, Madan JC, Emond JA, Morrison HG, Christensen BC, Karagas MR, Hoen AG
Microbiome. 2018 Jul 5;6(1):109. doi: 10.1186/s40168-018-0490-8. Epub 2018 Jul 5.
PMID: 29973274

Urine and toenail cadmium levels in pregnant women: A reliability study.
White AJ, O'Brien KM, Jackson BP, Karagas MR
Environ Int. 2018 Sep;118:86-91. doi: 10.1016/j.envint.2018.05.030. Epub 2018 May 29.
PMID: 29857281

The premature infant gut microbiome during the first 6 weeks of life differs based on gestational maturity at birth.
Chernikova DA, Madan JC, Housman ML, Zain-Ul-Abideen M, Lundgren SN, Morrison HG, Sogin ML, Williams SM, Moore JH, Karagas MR, Hoen AG
Pediatr Res. 2018 Jul;84(1):71-79. doi: 10.1038/s41390-018-0022-z. Epub 2018 May 23.
PMID: 29795209