Margaret Rita Karagas, PhD
Title(s):
Chair and Professor of Epidemiology
Professor of Community and Family Medicine
James W. Squires Professor
Additional Titles/Positions/Affiliations:
Director, Children's Environmental Health and Disease Prevention Research Center and Center for Molecular Epidemiology
Department(s):
Epidemiology
Community and Family Medicine
Education:
University of Washington, PhD 1990
Programs:
Norris Cotton Cancer Center
Quantitative Biomedical Sciences
Websites:
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Contact Information:
Department of Epidemiology
1 Medical Center Drive
7927 Rubin Building
Lebanon NH 03756
Office: 863 Rubin Bldg Lebanon, NH
Phone: 603-653-9010
Fax: 603-653-9093
Email: Margaret.Karagas@dartmouth.edu
Assistant: Kara Caputo
Asst. Phone: 603-653-9022
Asst. Email: Kara.L.Caputo@dartmouth.edu
Professional Interests:
Professor Karagas' research encompasses several epidemiological studies focusing on the etiology and prevention of human cancers, as well as adverse pregnancy and children's health outcomes. These include investigations to determine incidence rates of basal cell and squamous cell skin cancer for a geographically defined US population, and to assess the extent of any increase over the past 20 years. Another aspect of this research is a case-control study of these malignancies to identify risks associated with emerging exposures such as indoor tanning, ingestion of arsenic-containing drinking water and foods, immunosuppressive therapies and other factors. This research has been extended to bladder cancer. One of her current initiatives involves establishing a cohort of pregnant women in New Hampshire to assess the potential impact of arsenic and other exposures on risk of maternal and child health. Her ongoing work further includes studies of melanoma in women and collaborative investigations of exposure biomarkers, individual susceptibility, and biological response to environmental agents. Professor Karagas is one of the Principal Investigators of a NCI-funded cross-disciplinary postdoctoral training grant, serves as a mentor for early career investigators and participates in a variety of courses at the undergraduate and graduate level.
Selected Publications: |
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Maternal serum perfluoroalkyl substance mixtures and thyroid hormone concentrations in maternal and cord sera: The HOME Study. Metals and trace elements in relation to body mass index in a prospective study of US women. Reliability of stool microbiome methods for DNA yields and sequencing among infants and young children. Nutrient-toxic element mixtures and the early postnatal gut microbiome in a United States longitudinal birth cohort. Cosmetic tattooing and early onset basal cell carcinoma: a population-based case-control study from New Hampshire. Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program. Selenium-associated DNA methylation modifications in placenta and neurobehavioral development of newborns: An epigenome-wide study of two U.S. birth cohorts. Prediagnostic breast milk DNA methylation alterations in women who develop breast cancer. Microbial Communities in Human Milk Relate to Measures of Maternal Weight. Diesel exhaust and bladder cancer risk by pathologic stage and grade subtypes. |
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