Margaret Rita Karagas, PhD
Title(s)
Chair and Professor of Epidemiology
Professor of Community and Family Medicine
James W. Squires Professor
Additional Titles/Positions/Affiliations
Director, Children's Environmental Health and Disease Prevention Research Center and Center for Molecular Epidemiology
Department(s)
Epidemiology
Community and Family Medicine
Education
University of Washington, PhD 1990
Programs
Norris Cotton Cancer Center
Quantitative Biomedical Sciences
Websites
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Contact Information
Department of Epidemiology
1 Medical Center Drive
7927 Rubin Building
Lebanon NH 03756
Office: 863 Rubin Bldg Lebanon, NH
Phone: 603-653-9010
Fax: 603-653-9093
Email: Margaret.Karagas@dartmouth.edu
Assistant: Evan Vickers
Asst. Phone: 603-650-1918
Asst. Email: Evan.G.Vickers@dartmouth.edu
Professional Interests
Professor Karagas' research encompasses several epidemiological studies focusing on the etiology and prevention of human cancers over the lifecourse, as well as adverse pregnancy and children's health outcomes. These include investigations to determine incidence rates of basal cell and squamous cell skin cancer for a geographically defined US population, and to assess the extent of any increase over the past 20 years. Another aspect of this research is a case-control study of these malignancies to identify risks associated with emerging exposures such as indoor tanning, ingestion of arsenic-containing drinking water and foods, immunosuppressive therapies and other factors. This research has been extended to bladder cancer. One of her current initiatives involves establishing a cohort of pregnant women in New Hampshire to assess the potential impact of arsenic and other exposures on risk of maternal and child health. Her ongoing work further includes studies of melanoma in women and collaborative investigations of exposure biomarkers, individual susceptibility, and biological response to environmental agents. Professor Karagas is one of the Principal Investigators of a NCI-funded cross-disciplinary postdoctoral training grant, serves as a mentor for early career investigators and participates in a variety of courses at the undergraduate and graduate level.
Selected Publications |
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Placental microRNAs relate to early childhood growth trajectories. The association between early life antibiotic exposure and the gut resistome of young children: a systematic review. Adaptive-mixture-categorization (AMC)-based g-computation and its application to trace element mixtures and bladder cancer risk. Bladder cancer prognosis using deep neural networks and histopathology images. Dietary Exposure to Toxic Elements and the Health of Young Children: Methodological Considerations and Data Needs. Impact of the COVID-19 pandemic on children's sleep habits: an ECHO study. Gestational per- and polyfluoroalkyl substances exposure and infant body mass index trajectory in the New Hampshire Birth Cohort Study. Prenatal lead (Pb) exposure is associated with differential placental DNA methylation and hydroxymethylation in a human population. Arsenic exposure and respiratory outcomes during childhood in the INMA study. Exposure to melamine and its derivatives and aromatic amines among pregnant women in the United States: The ECHO Program. |
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