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Margaret Rita Karagas, PhD

Chair and Professor of Epidemiology
Professor of Community and Family Medicine
James W. Squires Professor

Additional Titles/Positions/Affiliations:
Director, Children's Environmental Health and Disease Prevention Research Center and Center for Molecular Epidemiology

Community and Family Medicine

University of Washington, PhD 1990

Norris Cotton Cancer Center
Quantitative Biomedical Sciences


Contact Information:

Department of Epidemiology
1 Medical Center Drive
7927 Rubin Building
Lebanon NH 03756

Office: 863 Rubin Bldg Lebanon, NH
Phone: 603-653-9010
Fax: 603-653-9093

Assistant: Kara Caputo
Asst. Phone: 603-653-9022
Asst. Email:

Professional Interests:

Professor Karagas' research encompasses several epidemiological studies focusing on the etiology and prevention of human cancers, as well as adverse pregnancy and children's health outcomes. These include investigations to determine incidence rates of basal cell and squamous cell skin cancer for a geographically defined US population, and to assess the extent of any increase over the past 20 years. Another aspect of this research is a case-control study of these malignancies to identify risks associated with emerging exposures such as indoor tanning, ingestion of arsenic-containing drinking water and foods, immunosuppressive therapies and other factors. This research has been extended to bladder cancer. One of her current initiatives involves establishing a cohort of pregnant women in New Hampshire to assess the potential impact of arsenic and other exposures on risk of maternal and child health. Her ongoing work further includes studies of melanoma in women and collaborative investigations of exposure biomarkers, individual susceptibility, and biological response to environmental agents. Professor Karagas is one of the Principal Investigators of a NCI-funded cross-disciplinary postdoctoral training grant, serves as a mentor for early career investigators and participates in a variety of courses at the undergraduate and graduate level.

Selected Publications:


A Machine Learning Approach for Long-Term Prognosis of Bladder Cancer based on Clinical and Molecular Features.
Song Q, Seigne JD, Schned AR, Kelsey KT, Karagas MR, Hassanpour S
AMIA Jt Summits Transl Sci Proc. 2020;2020:607-616. Epub 2020 May 30.
PMID: 32477683

Assessment of Maternal Glycemia and Newborn Size Among Pregnant Women Who Use Wood Stoves in Northern New England.
Fleisch AF, Seshasayee SM, Garshick E, Chipman JW, Koutrakis P, Baker ER, Karagas MR
JAMA Netw Open. 2020 May 1;3(5):e206046. doi: 10.1001/jamanetworkopen.2020.6046. Epub 2020 May 1.
PMID: 32463466

The Authors Respond.
Karagas MR, Barton D, Zens MS, Gilbert-Diamond D, Marmarelis EL
Epidemiology. 2020 Apr 22; doi: 10.1097/EDE.0000000000001205. Epub 2020 Apr 22.
PMID: 32366753

A data mining approach to investigate food groups related to incidence of bladder cancer in the BLadder cancer Epidemiology and Nutritional Determinants International Study.
Yu EYW, Wesselius A, Sinhart C, Wolk A, Stern MC, Jiang X, Tang L, Marshall J, Kellen E, van den Brandt P, Lu CM, Pohlabeln H, Steineck G, Allam MF, Karagas MR, La Vecchia C, Porru S, Carta A, Golka K, Johnson KC, Benhamou S, Zhang ZF, Bosetti C, Taylor JA, Weiderpass E, Grant EJ, White E, Polesel J, Zeegers MPA
Br J Nutr. 2020 Apr 23;:1-9. doi: 10.1017/S0007114520001439. Epub 2020 Apr 23.
PMID: 32321598

Risk of melanoma following keratinocyte malignancies.
Robinson SN, Zens MS, Rees JR, Barton DT, Karagas MR
Int J Cancer. 2020 Apr 14; doi: 10.1002/ijc.33011. Epub 2020 Apr 14.
PMID: 32285932

Toenail-Based Metal Concentrations and Young-Onset Breast Cancer.
O'Brien KM, White AJ, Jackson BP, Karagas MR, Sandler DP, Weinberg CR
Am J Epidemiol. 2019 Nov 1;188(4):34-43. doi: 10.1093/aje/kwaa035.
PMID: 32242893

Maternal serum perfluoroalkyl substance mixtures and thyroid hormone concentrations in maternal and cord sera: The HOME Study.
Lebeaux RM, Doherty BT, Gallagher LG, Zoeller RT, Hoofnagle AN, Calafat AM, Karagas MR, Yolton K, Chen A, Lanphear BP, Braun JM, Romano ME
Environ Res. 2020 Jun;185:109395. doi: 10.1016/j.envres.2020.109395. Epub 2020 Mar 16.
PMID: 32222633

Metals and trace elements in relation to body mass index in a prospective study of US women.
Niehoff NM, Keil AP, O'Brien KM, Jackson BP, Karagas MR, Weinberg CR, White AJ
Environ Res. 2020 May;184:109396. doi: 10.1016/j.envres.2020.109396. Epub 2020 Mar 16.
PMID: 32209500

Reliability of stool microbiome methods for DNA yields and sequencing among infants and young children.
Antosca K, Hoen AG, Palys T, Hilliard M, Morrison HG, Coker M, Madan J, Karagas MR
Microbiologyopen. 2020 May;9(5):e1018. doi: 10.1002/mbo3.1018. Epub 2020 Mar 12.
PMID: 32166902

Nutrient-toxic element mixtures and the early postnatal gut microbiome in a United States longitudinal birth cohort.
Laue HE, Moroishi Y, Jackson BP, Palys TJ, Madan JC, Karagas MR
Environ Int. 2020 May;138:105613. doi: 10.1016/j.envint.2020.105613. Epub 2020 Mar 3.
PMID: 32142916

View more publications on PubMed