Yina H. Huang, PhD
Associate Professor of Microbiology and Immunology
Associate Professor of Pathology & Laboratory Medicine
Microbiology and Immunology
Pathology & Laboratory Medicine
Molecular and Cellular Biology Graduate Programs
Norris Cotton Cancer Center
We investigate how T cells traffic and respond to infections. In particular, we study the signals that regulate T cell migration and activation to ensure protective immunity while preventing autoimmunity and immunodeficiency disease.
Author Correction: Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis.
IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis.
Resident memory T cells in the skin mediate durable immunity to melanoma.
Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis.
Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer.
Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.
Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease.
Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses.
Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.
Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.