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James O'Malley, MS, PhD

Professor of The Dartmouth Institute
Professor of Biomedical Data Science

Additional Titles/Positions/Affiliations:
Professor of Biomedical Data Science

The Dartmouth Institute
Biomedical Data Science

1994 B.Sc. (Hons) in Statistics: University of Canterbury, New Zealand
1999 M.S. in Applied Statistics: Purdue University, West Lafayette, Indiana
1999 Ph.D. in Statistics: University of Canterbury, New Zealand
2001 Postdoctoral-fellowship in Biostatistics: Harvard Medical School, Boston, Massachusetts

Norris Cotton Cancer Center
Quantitative Biomedical Sciences
The Dartmouth Institute for Health Policy and Clinical Practice


Contact Information:

The Dartmouth Institute
Williamson Translational Research Building
1 Medical Center Drive
Lebanon NH 03756

Office: 544
Phone: 603-653-0854
Fax: 603-653-0896

Assistant: Joel R. King
Asst. Phone: 603-653-3504
Asst. Email:

Professional Interests:

My research interests span both statistical methodology and various areas of medicine and health care. My prior and ongoing contributions to statistical methodology involve Bayesian statistics, statistical inference for social networks, multivariate hierarchical models, and comparative effectiveness research including causal inference for both randomized and observational studies. Specific research projects are typically motivated by problems encountered in my collaborative work with physicians, sociologists, health economists, health services researchers, epidemiologists and others. Application areas of focus include evaluating the relationship between health and social networks, evaluation/estimation of variations in health quality and outcomes, vascular surgery and cardiology, and evaluation of medical devices.

Rotations and Thesis Projects:

Statistical Methods:
- Analysis of Social Network Data
- Multivariate-Multilevel Models
- Comparative Effectiveness Research (Causal Inference)
- Bayesian Analysis
- Design and Analysis of Medical Device Clinical Trials

Collaborative Work:
- The measurement and reporting of health care quality
- Social networks and health
- Diffusion of medical technology
- Tracking health systems
- Comparative effectiveness in vascular surgery
- Comparative effectiveness in cardiology
- Comparative effectiveness in mental health

Grant Information:

Projects currently leading:

PCORI ME-1503-28261 (O’Malley PI) 01/01/2016-03/31/2019
Advancing Patient-Centered Outcomes Research in Survival Data with Unmeasured Confounding to Improve Patient Risk Communication

NIH/NIA P01AG019783 (Skinner PI) 07/01/2001-11/30/2023
Causes and Consequences of Healthcare Efficiency
PI: Statistical and Network Analysis Core

AHRQ U19HS024075 (Fisher PI) 09/01/2015-08/31/2020
Accelerating the Use of Evidence-Based Innovations in Healthcare Systems
PI: Data Core

Notable completed projects:

NIH 1U01 AG046830 (Skinner PI), 09/30/2013-06/30/2018
Diffusion of Medical Technology and Effects on Outcomes and Expenditures
Project Leader: Methods for Modeling the Diffusion of Implantable Cardiac Defibrillators

NIH 1R01HL109263-01A1 (O’Malley, Subramanian PIs) 04/01/2012-03/31/2015
Proximity to Food Establishments and BMI in the Framingham Heart Study

NIH 1RC4MH092717-01 (O’Malley PI), 10/01/2010-09/27/2013
Accounting for confounding bias and heterogeneity in comparative effectiveness

NIH/NIA P01 AG0309301 (Christakis PI), 04/15/2008-03/31/2013
Networks and Neighborhoods
Project Leader: Methods for the Analysis of Longitudinal Social Network Data

Courses Taught:

2018- Biostatistics III: Statistical Analysis of Complex Data (QBS 122)
2013-2014 Advanced Statistical Methods (ECS.245.1-TFA13)
2014-2018 The Practice of Statistics in Medicine (ECS.245.1-TFA13)


In 2011 I received the Mid-career Excellence award from the Health Policy Section of the ASA and in 2012 became an elected fellow of the ASA.

I was chair of the Health Policy Statistics Section of the America Statistical Association (ASA) in 2008, co-chair of the 2011 International Conference on Health Policy Statistics, and am an Associate Editor at Statistics in Medicine.

I was one of the organizers of the Dartmouth Interdisciplinary Network Research (DINR) seminar series (

Mentoring Information:

Post-doctoral fellows
2015-2018 Erika Moen, R25 Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2015-2017 Weston Viles, R25 Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2016-2018 Pablo Martinez-Camblor, Postdoctoral Fellow, Geisel School of Medicine at Dartmouth

PhD Students
2017- Guanqing Chen, Ph.D. Candidate, Program in Quantitative Biomedical Science
2017- Carly Bobak (Co-advisor), Program in Quantitative Biomedical Science
2017 - Chuankai An (Co-advisor), Computer Science
2018- Xin Ran, Program in Quantitative Biomedical Science

PhD Student Committees
2014-2017 Elizabeth Nichols, Ph.D. Candidate, Program in Health Policy and Clinical Practice
2018- Helen Newton, Ph.D. Candidate, Program in Health Policy and Clinical Practice

Selected Publications:


Financial Integration's Impact On Care Delivery And Payment Reforms: A Survey Of Hospitals And Physician Practices.
Fisher ES, Shortell SM, O'Malley AJ, Fraze TK, Wood A, Palm M, Colla CH, Rosenthal MB, Rodriguez HP, Lewis VA, Woloshin S, Shah N, Meara E
Health Aff (Millwood). 2020 Aug;39(8):1302-1311. doi: 10.1377/hlthaff.2019.01813.
PMID: 32744948

Don't dismiss logistic regression: the case for sensible extraction of interactions in the era of machine learning.
Levy JJ, O'Malley AJ
BMC Med Res Methodol. 2020 Jun 29;20(1):171. doi: 10.1186/s12874-020-01046-3. Epub 2020 Jun 29.
PMID: 32600277

Routine patient-reported experience measurement of shared decision-making in the USA: a qualitative study of the current state according to frontrunners.
Forcino RC, Meinders MJ, Engel JA, O'Malley AJ, Elwyn G
BMJ Open. 2020 Jun 7;10(6):e037087. doi: 10.1136/bmjopen-2020-037087. Epub 2020 Jun 7.
PMID: 32513894

Flattening the Mental Health Curve: COVID-19 Stay-at-Home Orders Are Associated With Alterations in Mental Health Search Behavior in the United States.
Jacobson NC, Lekkas D, Price G, Heinz MV, Song M, O'Malley AJ, Barr PJ
JMIR Ment Health. 2020 Jun 1;7(6):e19347. doi: 10.2196/19347. Epub 2020 Jun 1.
PMID: 32459186

Opportunities and Challenges of Claims-Based Quality Assessment: The Case of Postdischarge β-Blocker Treatment in Patients With Heart Failure With Reduced Ejection Fraction.
Gilstrap L, Skinner JS, Gladders B, O'Malley AJ, Barnato AE, Tosteson ANA, Austin AM
Circ Cardiovasc Qual Outcomes. 2020 Mar;13(3):e006180. doi: 10.1161/CIRCOUTCOMES.119.006180. Epub 2020 Mar 9.
PMID: 32148101

Modeling peer effect modification by network strength: The diffusion of implantable cardioverter defibrillators in the US hospital network.
O'Malley AJ, Moen EL, Bynum JPW, Austin AM, Skinner JS
Stat Med. 2020 Apr 15;39(8):1125-1144. doi: 10.1002/sim.8466. Epub 2020 Jan 11.
PMID: 31925971

Association of Physician Peer Influence With Subsequent Physician Adoption and Use of Bevacizumab.
Keating NL, O'Malley AJ, Onnela JP, Gray SW, Landon BE
JAMA Netw Open. 2020 Jan 3;3(1):e1918586. doi: 10.1001/jamanetworkopen.2019.18586. Epub 2020 Jan 3.
PMID: 31899533

Medical Students' Knowledge and Attitudes Toward Shared Decision Making: Results From a Multinational, Cross-Sectional Survey.
Yen RW, Barr PJ, Cochran N, Aarts JW, Legare F, Reed M, O'Malley AJ, Scalia P, Painchaud Guerard G, Backer G, Reilly C, Elwyn G, Durand MA
MDM Policy Pract. 2019 Jul-Dec;4(2):2381468319885871. doi: 10.1177/2381468319885871. Epub 2019 Nov 8.
PMID: 31742232

Association of Receiving Multiple, Concurrent Fracture-Associated Drugs With Hip Fracture Risk.
Emeny RT, Chang CH, Skinner J, O'Malley AJ, Smith J, Chakraborti G, Rosen CJ, Morden NE
JAMA Netw Open. 2019 Nov 1;2(11):e1915348. doi: 10.1001/jamanetworkopen.2019.15348. Epub 2019 Nov 1.
PMID: 31722031

Implementation of the uterine fibroids Option Grid patient decision aids across five organizational settings: a randomized stepped-wedge study protocol.
Scalia P, Durand MA, Forcino RC, Schubbe D, Barr PJ, O'Brien N, O'Malley AJ, Foster T, Politi MC, Laughlin-Tommaso S, Banks E, Madden T, Anchan RM, Aarts JWM, Velentgas P, Balls-Berry J, Bacon C, Adams-Foster M, Mulligan CC, Venable S, Cochran NE, Elwyn G
Implement Sci. 2019 Sep 2;14(1):88. doi: 10.1186/s13012-019-0933-z. Epub 2019 Sep 2.
PMID: 31477140

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