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James O'Malley, MS, PhD

Contact Information

Professional Interests

My research interests span both statistical methodology and various areas of medicine and health care. My prior and ongoing contributions to statistical methodology involve statistical inference for social networks, multivariate hierarchical models, comparative effectiveness research including causal inference for both randomized and observational studies, and Bayesian analysis. Specific research projects are typically motivated by problems encountered in my collaborative work with physicians, sociologists, health economists, health services researchers, epidemiologists and others. Application areas of focus include evaluating the relationship between health and social networks, evaluation/estimation of variations in health quality and outcomes, vascular surgery and cardiology, and evaluation of medical devices.

Rotations and Thesis Projects

Statistical Methods:
- Analysis of Social Network Data
- Multivariate-Multilevel Models
- Comparative Effectiveness Research (Causal Inference)
- Bayesian Analysis
- Design and Analysis of Medical Device Clinical Trials

Collaborative Work:
- Social networks and health
- The measurement and reporting of health care quality
- Diffusion of medical technology
- Tracking health systems
- Comparative effectiveness in vascular surgery
- Comparative effectiveness in cardiology
- Comparative effectiveness in mental health

Grant Information

Projects currently leading or in a leading role:

NIH/NLM R01LM014233 (O'Malley PI)
8/1/2024-05/31/2028
Geographic Variations in Health Care: Overcoming Bias, Expanding Generalizability, and Improving Relevance

NIH/NIA P01AG019783 (Barnato PI)
10/01/2023-09/30/2028
Causes and Consequences of Healthcare Inequity in Alzheimer's Disease and Related Dementias
PI: Statistical and Network Analysis Core

NIH/NIA, P20GM148278 (Creager PI)
03/01/2023-02/29/2028
Center for Rural Health Care Delivery Science
PI: Statistical, Informatics and Qualitative Methods Core

IHS-2018C2-12902-IC (Leyenaar PI)
7/1/2019 - 6/30/2023
Comparative Effectiveness of Direct Admission & Admission through Emergency Departments for Children
PI: Sub-contract

NIH, (Multiple-PIs: Brown, Loftus, O'Malley)
2021-2026
The BASIC trial: Improving implementation of evidence-based approaches and surveillance to prevent bacterial transmission and infection.
Multiple principle investigators

PCS-2017C2-7724-IC (Pratt PI)
2/15/2019 - 2/14/2024
Integrated Physical and Mental Health Self-management Compared to Chronic Disease Self-management
PI: Sub-contract

Notable completed projects:

PCORI ME-1503-28261 (O’Malley PI)
01/01/2016-03/31/2019
Advancing Patient-Centered Outcomes Research in Survival Data with Unmeasured Confounding to Improve Patient Risk Communication

NIH, 2P01AG019783-16 (Skinner PI)
02/01/2018-09/30/2023
Causes and Consequences of Healthcare Efficiency
PI: Statistical and Network Analysis Core

1U01 AG046830 (Skinner PI)
09/30/2013-06/30/2018
Diffusion of Medical Technology and Effects on Outcomes and Expenditures
Project Leader: Methods for Modeling the Diffusion of Implantable Cardiac Defibrillators

NIH 1R01HL109263-01A1 (O’Malley, Subramanian PIs) 04/01/2012-03/31/2015
Proximity to Food Establishments and BMI in the Framingham Heart Study

NIH 1RC4MH092717-01 (O’Malley PI)
10/01/2010-09/27/2013
Accounting for confounding bias and heterogeneity in comparative effectiveness

NIH/NIA P01 AG0309301 (Christakis PI),
04/15/2008-03/31/2013
Networks and Neighborhoods
Project Leader: Methods for the Analysis of Longitudinal Social Network Data

NIH RO1 HS025408 (Landon PI)
9/30/2017 - 7/31/2021
Identifying Predictors of Hospital Admission from the ED Among the Elderly
PI: Sub-contract

Courses Taught

2018- Biostatistics III: Statistical Analysis of Complex Data (QBS 122)
2014-2018 The Practice of Statistics in Medicine (ECS.245.1-TFA13)
2013-2014 Advanced Statistical Methods (ECS.245.1-TFA13)

Mentoring Information

Post-doctoral fellows
2007-2009 Brian Neelon, Postdoctoral Fellow, Harvard Medical School
2010-2012 Sudeshna Paul, Postdoctoral Fellow, Harvard Medical School
2011-2014 Jaeun Choi, Postdoctoral Fellow, Harvard Medical School
2015-2018 Erika Moen, R25 Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2015-2017 Weston Viles, R25 Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2016-2018 Pablo Martinez-Camblor, Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2018-2020 Seho Park, Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2021-2022 Carly Bobak, Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2024-Current Chun-Che Wen, Postdoctoral Fellow, Geisel School of Medicine at Dartmouth

PhD Students
2017-2021 Guanqing Chen, Ph.D. Candidate, Program in Quantitative Biomedical Science
2017-2021 Carly Bobak (Co-advisor), Program in Quantitative Biomedical Science
2017-2019 Chuankai An (Co-advisor), Computer Science
2018- Xin Ran, Program in Quantitative Biomedical Science
2022- Bo Qin, Program in Quantitative Biomedical Science
2022- Haobin (Tony) Chen, Program in Quantitative Biomedical Science
2024- Yifan Zhao, Program in Quantitative Biomedical Science

PhD Committees
2014-2017 Elizabeth Nichols, Program in Health Policy and Clinical Practice
2018-2020 Helen Newton, Program in Health Policy and Clinical Practice
2019- Renata West Yen, Program in Health Policy and Clinical Practice
2020-2022 Reed Bratches, Program in Health Policy and Clinical Practice
2020-2022 Catherine Pollack, Program in Quantitative Biomedical Science
2020-2021 Joshua Levy, Program in Quantitative Biomedical Science
2022- Sarah Cornelius, Program in Quantitative Biomedical Science
2022- Bruno Scodari, Program in Quantitative Biomedical Science
2022- Min Young Kim, Health Policy and Clinical Practice

Biography

Received the Mid-career Excellence award from the Health Policy Section of the ASA and in 2012 became an elected fellow of the ASA. In 2019, was the recipient of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Award for Excellence in Methodology in Health Economics and Outcomes Research. In 2021, received the Peggy Y. Thomson Professorship in the Evaluative Clinical Sciences

Chair of the Health Policy Statistics Section of the America Statistical Association (ASA) in 2008, co-chair of the 2011 International Conference on Health Policy Statistics. Currently, an Associate Editor at Statistics in Medicine and of Observational Studies.

Co-organizer of the Dartmouth Interdisciplinary Network Research (DINR) seminar series (http://www.dartmouth.edu/~dinr/).