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James O'Malley, MS, PhD

Title(s):
Professor of The Dartmouth Institute
Professor of Biomedical Data Science

Additional Titles/Positions/Affiliations:
Professor of Biomedical Data Science

Department(s):
The Dartmouth Institute
Biomedical Data Science

Education:
1994 B.Sc. (Hons) in Statistics: University of Canterbury, New Zealand
1999 M.S. in Applied Statistics: Purdue University, West Lafayette, Indiana
1999 Ph.D. in Statistics: University of Canterbury, New Zealand
2001 Postdoctoral-fellowship in Biostatistics: Harvard Medical School, Boston, Massachusetts

Programs:
Norris Cotton Cancer Center
Quantitative Biomedical Sciences
SYNERGY
The Dartmouth Institute for Health Policy and Clinical Practice

Websites:
http://tdi.dartmouth.edu/faculty/a-james-omalley-phd
https://bmds.dartmouth.edu/
https://geiselmed.dartmouth.edu/qbs/
http://www.dartmouth.edu/~dinr/
https://www.c4tbh.org/the-center/

Contact Information:

The Dartmouth Institute
Williamson Translational Research Building
1 Medical Center Drive
Lebanon NH 03756

Office: 544
Phone: 603-653-0854
Fax: 603-653-0896
Email: James.OMalley@Dartmouth.edu

Assistant: Joel R. King
Asst. Phone: 603-653-3504
Asst. Email: Joel.R.King@dartmouth.edu


Professional Interests:

My research interests span both statistical methodology and various areas of medicine and health care. My prior and ongoing contributions to statistical methodology involve Bayesian statistics, statistical inference for social networks, multivariate hierarchical models, and comparative effectiveness research including causal inference for both randomized and observational studies. Specific research projects are typically motivated by problems encountered in my collaborative work with physicians, sociologists, health economists, health services researchers, epidemiologists and others. Application areas of focus include evaluating the relationship between health and social networks, evaluation/estimation of variations in health quality and outcomes, vascular surgery and cardiology, and evaluation of medical devices.

Rotations and Thesis Projects:

Statistical Methods:
- Analysis of Social Network Data
- Multivariate-Multilevel Models
- Comparative Effectiveness Research (Causal Inference)
- Bayesian Analysis
- Design and Analysis of Medical Device Clinical Trials

Collaborative Work:
- The measurement and reporting of health care quality
- Social networks and health
- Diffusion of medical technology
- Tracking health systems
- Comparative effectiveness in vascular surgery
- Comparative effectiveness in cardiology
- Comparative effectiveness in mental health

Grant Information:

Projects currently leading:

PCORI ME-1503-28261 (O’Malley PI) 01/01/2016-03/31/2019
Advancing Patient-Centered Outcomes Research in Survival Data with Unmeasured Confounding to Improve Patient Risk Communication

NIH/NIA P01AG019783 (Skinner PI) 07/01/2001-11/30/2023
Causes and Consequences of Healthcare Efficiency
PI: Statistical and Network Analysis Core

AHRQ U19HS024075 (Fisher PI) 09/01/2015-08/31/2020
Accelerating the Use of Evidence-Based Innovations in Healthcare Systems
PI: Data Core

Notable completed projects:

NIH 1U01 AG046830 (Skinner PI), 09/30/2013-06/30/2018
Diffusion of Medical Technology and Effects on Outcomes and Expenditures
Project Leader: Methods for Modeling the Diffusion of Implantable Cardiac Defibrillators

NIH 1R01HL109263-01A1 (O’Malley, Subramanian PIs) 04/01/2012-03/31/2015
Proximity to Food Establishments and BMI in the Framingham Heart Study

NIH 1RC4MH092717-01 (O’Malley PI), 10/01/2010-09/27/2013
Accounting for confounding bias and heterogeneity in comparative effectiveness

NIH/NIA P01 AG0309301 (Christakis PI), 04/15/2008-03/31/2013
Networks and Neighborhoods
Project Leader: Methods for the Analysis of Longitudinal Social Network Data

Courses Taught:

2018- Biostatistics III: Statistical Analysis of Complex Data (QBS 122)
2013-2014 Advanced Statistical Methods (ECS.245.1-TFA13)
2014-2018 The Practice of Statistics in Medicine (ECS.245.1-TFA13)

Biography:

In 2011 I received the Mid-career Excellence award from the Health Policy Section of the ASA and in 2012 became an elected fellow of the ASA.

I was chair of the Health Policy Statistics Section of the America Statistical Association (ASA) in 2008, co-chair of the 2011 International Conference on Health Policy Statistics, and am an Associate Editor at Statistics in Medicine.

I was one of the organizers of the Dartmouth Interdisciplinary Network Research (DINR) seminar series (http://www.dartmouth.edu/~dinr/).

Mentoring Information:

Post-doctoral fellows
2015-2018 Erika Moen, R25 Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2015-2017 Weston Viles, R25 Postdoctoral Fellow, Geisel School of Medicine at Dartmouth
2016-2018 Pablo Martinez-Camblor, Postdoctoral Fellow, Geisel School of Medicine at Dartmouth

PhD Students
2017- Guanqing Chen, Ph.D. Candidate, Program in Quantitative Biomedical Science
2017- Carly Bobak (Co-advisor), Program in Quantitative Biomedical Science
2017 - Chuankai An (Co-advisor), Computer Science
2018- Xin Ran, Program in Quantitative Biomedical Science

PhD Student Committees
2014-2017 Elizabeth Nichols, Ph.D. Candidate, Program in Health Policy and Clinical Practice
2018- Helen Newton, Ph.D. Candidate, Program in Health Policy and Clinical Practice


Selected Publications:

 

Landscape of Health Systems in the United States.
Furukawa MF, Machta RM, Barrett KA, Jones DJ, Shortell SM, Scanlon DP, Lewis VA, O'Malley AJ, Meara ER, Rich EC
Med Care Res Rev. 2019 Jan 23;:1077558718823130. doi: 10.1177/1077558718823130. Epub 2019 Jan 23.
PMID: 30674227

Comparing Long-term Mortality After Carotid Endarterectomy vs Carotid Stenting Using a Novel Instrumental Variable Method for Risk Adjustment in Observational Time-to-Event Data.
Columbo JA, Martinez-Camblor P, MacKenzie TA, Staiger DO, Kang R, Goodney PP, O'Malley AJ
JAMA Netw Open. 2018 Sep 7;1(5):e181676. doi: 10.1001/jamanetworkopen.2018.1676. Epub 2018 Sep 7.
PMID: 30646140

Adapting the Breast Cancer Surgery Decision Quality Instrument for Lower Socioeconomic Status: Improving Readability, Acceptability, and Relevance.
Durand MA, Song J, Yen RW, Sepucha K, Politi MC, Dhage S, Rosenkranz K, Margenthaler J, Tosteson ANA, Crayton E, Jackson S, Bradley A, O'Malley AJ, Volk RJ, Ozanne E, Percac-Lima S, Acosta J, Mir N, Scalia P, Ward A, Elwyn G
MDM Policy Pract. 2018 Jul-Dec;3(2):2381468318811839. doi: 10.1177/2381468318811839. Epub 2018 Nov 25.
PMID: 30515461

Modeling a bivariate residential-workplace neighborhood effect when estimating the effect of proximity to fast-food establishments on body mass index.
O'Malley AJ, James P, MacKenzie TA, Byun J, Subramanian SV, Block JP
Stat Med. 2019 Mar 15;38(6):1013-1035. doi: 10.1002/sim.8039. Epub 2018 Nov 20.
PMID: 30460712

Evaluating Breast Cancer Care Coordination at a Rural National Cancer Institute Comprehensive Cancer Center Using Network Analysis and Geospatial Methods.
Moen EL, Kapadia NS, O'Malley AJ, Onega T
Cancer Epidemiol Biomarkers Prev. 2019 Mar;28(3):455-461. doi: 10.1158/1055-9965.EPI-18-0771. Epub 2018 Oct 30.
PMID: 30377204

Instrumental Variable Based Estimation Under the Semiparametric Accelerated Failure Time Model.
Huling J, Yu M, O'Malley AJ
Biometrics. 2018 Oct 25; doi: 10.1111/biom.12985. Epub 2018 Oct 25.
PMID: 30357822

Estimation of an inter-rater intra-class correlation coefficient that overcomes common assumption violations in the assessment of health measurement scales.
Bobak CA, Barr PJ, O'Malley AJ
BMC Med Res Methodol. 2018 Sep 12;18(1):93. doi: 10.1186/s12874-018-0550-6. Epub 2018 Sep 12.
PMID: 30208858

Reporting of Baseline Characteristics to Accompany Analysis by Instrumental Variables.
MacKenzie TA, O'Malley AJ, Bekelis K
Epidemiology. 2018 Nov;29(6):817-820. doi: 10.1097/EDE.0000000000000914.
PMID: 30188381

Egocentric social networks and smoking among adults with serious mental illness.
Aschbrenner KA, Bobak C, Schneider EJ, Naslund JA, Brunette MF, O'Malley AJ
Transl Behav Med. 2018 Jul 17;8(4):531-539. doi: 10.1093/tbm/ibx014.
PMID: 30016519

Workshop on Emerging Technology and Data Analytics for Behavioral Health.
Kotz D, Lord SE, O'Malley AJ, Stark L, Marsch LA
JMIR Res Protoc. 2018 Jun 20;7(6):e158. doi: 10.2196/resprot.9589. Epub 2018 Jun 20.
PMID: 29925493

View more publications on PubMed