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John B. Weaver, PhD

Professor of Radiology


U. Arizona, BS 1977
U. Virginia, PHD 1983

Contact Information

Department of Radiology
DHMC, One Medical Center Drive
Lebanon NH 03756

Office: DHMC, Building 2, Level 3
Phone: 603-650-8270
Fax: 603-650-5455

Assistant: Wendi L. Jewell
Asst. Phone: 603-650-7443
Asst. Email:

Professional Interests

Interests include MR elastography, magnetic nanoparticle imaging, using magnetic nanoparticles as biomarkers for temperature and tissue stiffness, MR acquisition and pulse sequence development, digital image processing.

Grant Information

PI: R01 DK063013-01A2 NIH-NIDDK
Mapping the Mechanical Properties of the Diabetic Foot

PI: MR-Based Elasticity: Project I of Program Project P01 CA080138-05 (Paulsen)
Alternative Breast Cancer Imaging Modalities

PI: Project 2 “Spectroscopic Quantification of Ligand Binding in Vivo.”
“Dartmouth Center for Cancer Nanotechnology Excellence”
Source: NCI - Centers of Cancer Nanotechnology Excellence PI: Ian Baker

Selected Publications


Distinguishing Nanoparticle Aggregation from Viscosity Changes in MPS/MSB Detection of Biomarkers.
Jyoti D, Gordon-Wylie SW, Reeves DB, Paulsen KD, Weaver JB
Sensors (Basel). 2022 Sep 4;22(17) doi: 10.3390/s22176690. Epub 2022 Sep 4.
PMID: 36081147

One-Sided Multidimensional Statistical Significance Testing: A New Method of Calculating the Statistical Significance of Spectra Used to Demonstrate Magnetic Nanoparticle Sensitivity.
Weaver JB, Weaver CV, Ness DB, Gordon-Wylie SW, Demidenko E
J Phys D Appl Phys. 2022 Aug 11;55(32) pii: 325001. doi: 10.1088/1361-6463/ac7012. Epub 2022 May 26.
PMID: 35726230

Measuring protein biomarker concentrations using antibody tagged magnetic nanoparticles.
Gordon-Wylie SW, Ness DB, Shi Y, Mirza SK, Paulsen KD, Weaver JB
Biomed Phys Eng Express. 2020 Nov;6(6) doi: 10.1088/2057-1976/abc45b. Epub 2020 Nov 3.
PMID: 34676103

Poroelasticity as a Model of Soft Tissue Structure: Hydraulic Permeability Reconstruction for Magnetic Resonance Elastography in Silico.
Sowinski DR, McGarry MDJ, Van Houten EEW, Gordon-Wylie S, Weaver JB, Paulsen KD
Front Phys. 2021 Jan;8 pii: 617582. doi: 10.3389/fphy.2020.617582. Epub 2021 Jan 21.
PMID: 36340954

Poroelastic Mechanical Properties of the Brain Tissue of Normal Pressure Hydrocephalus Patients During Lumbar Drain Treatment Using Intrinsic Actuation MR Elastography.
Solamen LM, McGarry MDJ, Fried J, Weaver JB, Lollis SS, Paulsen KD
Acad Radiol. 2021 Apr;28(4):457-466. doi: 10.1016/j.acra.2020.03.009. Epub 2020 Apr 22.
PMID: 32331966

Identifying in vivo inflammation using magnetic nanoparticle spectra.
Weaver JB, Ness DB, Fields J, Jyoti D, Gordon-Wylie SW, Berwin BL, Mirza S, Fiering SN
Phys Med Biol. 2020 Jun 11;65(12):125003. doi: 10.1088/1361-6560/ab8afd. Epub 2020 Jun 11.
PMID: 32311682

Nonlinear Inversion MR Elastography With Low-Frequency Actuation.
Zeng W, Gordon-Wylie SW, Tan L, Solamen L, McGarry MDJ, Weaver JB, Paulsen KD
IEEE Trans Med Imaging. 2020 May;39(5):1775-1784. doi: 10.1109/TMI.2019.2958212. Epub 2019 Dec 6.
PMID: 31825863

Quantification of magnetic nanoparticles by compensating for multiple environment changes simultaneously.
Shi Y, Jyoti D, Gordon-Wylie SW, Weaver JB
Nanoscale. 2020 Jan 7;12(1):195-200. doi: 10.1039/c9nr08258a. Epub 2019 Dec 6.
PMID: 31807744

Concurrent quantification of magnetic nanoparticles temperature and relaxation time.
Shi Y, Weaver JB
Med Phys. 2019 Sep;46(9):4070-4076. doi: 10.1002/mp.13655. Epub 2019 Jul 12.
PMID: 31209904

Phantom evaluations of low frequency MR elastography.
Solamen LM, Gordon-Wylie SW, McGarry MD, Weaver JB, Paulsen KD
Phys Med Biol. 2019 Mar 12;64(6):065010. doi: 10.1088/1361-6560/ab0290. Epub 2019 Mar 12.
PMID: 30695755

View more publications on PubMed