Todd W Miller, PhD
Title(s)
Associate Professor of Molecular and Systems Biology
Additional Titles/Positions/Affiliations
Co-Director, Cancer Signaling, Genomes & Networks Research Program, Dartmouth Cancer Center
Scientific Director, Comprehensive Breast Program, Dartmouth Cancer Center
Co-Director, Molecular Tumor Board, Dartmouth Cancer Center
Department(s)
Molecular and Systems Biology
Education
University of Connecticut (Storrs, CT), B.S., Physiology & Neurobiology, 1998
University at Albany (Albany, NY), Ph.D. in Biomedical Sciences, 2004
Vanderbilt University (Nashville, TN), Post-doctoral Fellowship in Breast Cancer, 2004-2009
Programs
Molecular and Cellular Biology Graduate Programs
Norris Cotton Cancer Center
Websites
Lab website:
https:
Publications:
http:
Academic Analytics
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Contact Information
1 Medical Center Drive
Rubin Bldg, HB 7936
Lebanon NH 03756
Office: Rubin 604
Phone: 603-646-5507
Email: Todd.W.Miller@Dartmouth.edu
Professional Interests
Breast cancer, targeted therapeutics, signaling pathways, drug resistance, biomarker development
Biography
Dr. Miller received his B.S. in Physiology and Neurobiology at the University of Connecticut in 1998, and his Ph.D. in Biomedical Sciences at the State University of New York at Albany in 2004 (thesis: Immunization and single-chain Fv intrabody gene therapies for Huntington’s Disease). He did his postdoctoral training at Vanderbilt University (2004-2009), and served as a Research Faculty member 2009-2012. Dr. Miller joined the Geisel School of Medicine at Dartmouth in 2012.
Alternating 17beta-estradiol and aromatase inhibitor therapies is efficacious in post-menopausal women with advanced endocrine-resistant ER+ breast cancer. The role of cancer cell bioenergetics in dormancy and drug resistance. Alpelisib Efficacy without Cherry-PI3King Mutations. Tumour, whole-blood, plasma and tissue concentrations of metformin in lung cancer patients. High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer. Pan-Cancer Transcriptional Models Predicting Chemosensitivity in Human Tumors. Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer. Identification of Let-7f-5p as a novel biomarker of recurrence in non-muscle invasive bladder cancer. Molecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board. Plasma DNA as a "liquid biopsy" incompletely complements tumor biopsy for identification of mutations in a case series of four patients with oligometastatic breast cancer. |
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