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Jonathan D. Marotti, MD

Title(s)
Associate Professor of Pathology and Laboratory Medicine

Department(s)
Pathology and Laboratory Medicine

Education
Dartmouth Medical School, 2005
Anatomic and Clinical Pathology Residency, Beth Israel Deaconess Medical Center, 2005-2009
Breast Pathology Fellowship, Beth Israel Deaconess Medical Center, 2009-2010
Cytopathology Fellowship, Dartmouth-Hitchcock Medical Center, 2010-2011

Programs
Dartmouth Cancer Center

Contact Information


Professional Interests

Breast pathology
Cytopathology


Selected Publications

 

Quantitative proteomics analysis of triple-negative breast cancers.
Mariano NC, Marotti JD, Chen Y, Karakyriakou B, Salgado R, Christensen BC, Miller TW, Kettenbach AN
NPJ Precis Oncol. 2025 Apr 24;9(1):117. doi: 10.1038/s41698-025-00907-8. Epub 2025 Apr 24.
PMID: 40269124

Oxidative Phosphorylation Is a Metabolic Vulnerability of Endocrine Therapy-Tolerant Persister Cells in ER+ Breast Cancer.
Tau S, Chamberlin MD, Yang H, Marotti JD, Muskus PC, Roberts AM, Carmichael MM, Cressey L, Dragnev CPC, Demidenko E, Hampsch RA, Soucy SM, Kolling FW, Samkoe KS, Alvarez JV, Kettenbach AN, Miller TW
Cancer Res. 2025 Mar 14;85(6):1145-1161. doi: 10.1158/0008-5472.CAN-24-1204.
PMID: 39777474

Extensive epigenomic dysregulation is a hallmark of homologous recombination deficiency in triple-negative breast cancer.
Chen Y, Salas LA, Marotti JD, Jenkins NP, Cheng C, Miller TW, Kettenbach AN, Christensen BC
Int J Cancer. 2025 Mar 15;156(6):1191-1202. doi: 10.1002/ijc.35274. Epub 2024 Dec 5.
PMID: 39635770

A multi-model approach integrating whole-slide imaging and clinicopathologic features to predict breast cancer recurrence risk.
Goyal M, Marotti JD, Workman AA, Tooker GM, Ramin SK, Kuhn EP, Chamberlin MD, diFlorio-Alexander RM, Hassanpour S
NPJ Breast Cancer. 2024 Oct 20;10(1):93. doi: 10.1038/s41523-024-00700-z. Epub 2024 Oct 20.
PMID: 39426965

Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation.
Tau S, Chamberlin MD, Yang H, Marotti JD, Roberts AM, Carmichael MM, Cressey L, Dragnev C, Demidenko E, Hampsch RA, Soucy SM, Kolling F, Samkoe KS, Alvarez JV, Kettenbach AN, Miller TW
bioRxiv. 2024 Sep 27; pii: 2024.09.26.615177. doi: 10.1101/2024.09.26.615177. Epub 2024 Sep 27.
PMID: 39386444

Does ROSE matter? Evaluation of final diagnostic, PD-L1 immunohistochemistry, and molecular testing yields of CT-guided lung biopsies performed before and after the onset of the COVID-19 pandemic.
Jennings EB, Percarpio RB, Tafe LJ, Demidenko E, Levy J, Gutmann EJ, Marotti JD
J Am Soc Cytopathol. 2024 Jul-Aug;13(4):263-271. doi: 10.1016/j.jasc.2024.03.004. Epub 2024 Mar 29.
PMID: 38677893

Chondrolipoma of the Breast: A Myofibroblastoma Variant or a Distinct Lesion?
Workman AA, Green DC, Hughes EG, Shah PS, Cloutier JM, Marotti JD
Int J Surg Pathol. 2024 Dec;32(8):1525-1530. doi: 10.1177/10668969241231975. Epub 2024 Feb 14.
PMID: 38356303

Guar beans in a peritoneal fluid sample.
Gutmann EJ, Marotti JD
Cytopathology. 2024 May;35(3):425-426. doi: 10.1111/cyt.13351. Epub 2023 Dec 21.
PMID: 38126698

Sixteen-Year Institutional Review of Magnetic Resonance Imaging-Guided Breast Biopsies: Trends in Histologic Diagnoses With Radiologic Correlation.
Motanagh SA, Dwan D, Azizgolshani N, E Muller K, diFlorio-Alexander RM, Marotti JD
Breast Cancer (Auckl). 2023;17:11782234231215193. doi: 10.1177/11782234231215193. Epub 2023 Nov 28.
PMID: 38034324

Use of molecular testing results to analyze the overuse of atypia of undetermined significance in thyroid cytology.
Martinez Coconubo D, Levy JJ, Kerr DA, Vaickus LJ, Vidis L, Glass RE, Gutmann EJ, Marotti JD, Liu X
J Am Soc Cytopathol. 2023 Nov-Dec;12(6):451-460. doi: 10.1016/j.jasc.2023.09.002. Epub 2023 Sep 7.
PMID: 37775434

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