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Kimberley S Samkoe, PhD

Title(s):
Assistant Professor of Surgery

Additional Titles/Positions/Affiliations:
Adjunct Assistant Professor at Thayer School of Engineering

Department(s):
Surgery

Education:
Ph.D. - 2007 - Biophysical Chemistry, University of Calgary, Calgary, AB, Canada
B.Sc.Hons. - 2001 - Biochemsitry, University of Regina, Regina, SK, Canada

Programs:
Norris Cotton Cancer Center

Websites:
http://www.dartmouth.edu/optmed/
http://www.photobiology.org/

Contact Information:

536E Borwell
One Medical Center Drive
Dartmouth Hitchcock Memorial Center
Lebanon NH 03756

Office: 536E Borwell
Phone: 603-650-7618
Email: Kimberley.S.Samkoe@Dartmouth.edu

Selected Publications:
 

Application of Fluorescence-Guided Surgery to Subsurface Cancers Requiring Wide Local Excision: Literature Review and Novel Developments Toward Indirect Visualization.
Samkoe KS, Bates BD, Elliott JT, LaRochelle E, Gunn JR, Marra K, Feldwisch J, Ramkumar DB, Bauer DF, Paulsen KD, Pogue BW, Henderson ER
Cancer Control. 2018 Jan-Mar;25(1):1073274817752332. doi: 10.1177/1073274817752332.
PMID: 29334791

Development and evaluation of a connective tissue phantom model for subsurface visualization of cancers requiring wide local excision.
Samkoe KS, Bates BD, Tselepidakis NN, DSouza AV, Gunn JR, Ramkumar DB, Paulsen KD, Pogue BW, Henderson ER
J Biomed Opt. 2017 Dec;22(12):1-12. doi: 10.1117/1.JBO.22.12.121613.
PMID: 29274143

Assessing daylight & low-dose rate photodynamic therapy efficacy, using biomarkers of photophysical, biochemical and biological damage metrics in situ.
de Souza ALR, LaRochelle E, Marra K, Gunn J, Davis SC, Samkoe KS, Chapman MS, Maytin EV, Hasan T, Pogue BW
Photodiagnosis Photodyn Ther. 2017 Dec;20:227-233. doi: 10.1016/j.pdpdt.2017.10.005. Epub 2017 Oct 14.
PMID: 29037911

Toxicity and Pharmacokinetic Profile for Single-Dose Injection of ABY-029: a Fluorescent Anti-EGFR Synthetic Affibody Molecule for Human Use.
Samkoe KS, Gunn JR, Marra K, Hull SM, Moodie KL, Feldwisch J, Strong TV, Draney DR, Hoopes PJ, Roberts DW, Paulsen K, Pogue BW
Mol Imaging Biol. 2017 Aug;19(4):512-521. doi: 10.1007/s11307-016-1033-y.
PMID: 27909986

Simultaneous <i>In Vivo</i> Fluorescent Markers for Perfusion, Protoporphyrin Metabolism, and EGFR Expression for Optically Guided Identification of Orthotopic Glioma.
Elliott JT, Marra K, Evans LT, Davis SC, Samkoe KS, Feldwisch J, Paulsen KD, Roberts DW, Pogue BW
Clin Cancer Res. 2017 May 1;23(9):2203-2212. doi: 10.1158/1078-0432.CCR-16-1400. Epub 2016 Oct 31.
PMID: 27799250

Optical tracer size differences allow quantitation of active pumping rate versus Stokes-Einstein diffusion in lymphatic transport.
DSouza AV, Marra K, Gunn JR, Samkoe KS, Pogue BW
J Biomed Opt. 2016 Oct 1;21(10):100501. doi: 10.1117/1.JBO.21.10.100501.
PMID: 27752703

Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
de Souza AL, Marra K, Gunn J, Samkoe KS, Kanick SC, Davis SC, Chapman MS, Maytin EV, Hasan T, Pogue BW
Br J Cancer. 2016 Sep 27;115(7):805-13. doi: 10.1038/bjc.2016.267. Epub 2016 Aug 30.
PMID: 27575852

Review of fluorescence guided surgery systems: identification of key performance capabilities beyond indocyanine green imaging.
DSouza AV, Lin H, Henderson ER, Samkoe KS, Pogue BW
J Biomed Opt. 2016 Aug 1;21(8):80901. doi: 10.1117/1.JBO.21.8.080901.
PMID: 27533438

Fluorescent Affibody Molecule Administered In Vivo at a Microdose Level Labels EGFR Expressing Glioma Tumor Regions.
de Souza AL, Marra K, Gunn J, Samkoe KS, Hoopes PJ, Feldwisch J, Paulsen KD, Pogue BW
Mol Imaging Biol. 2017 Feb;19(1):41-48. doi: 10.1007/s11307-016-0980-7.
PMID: 27379987

Vision 20/20: Molecular-guided surgical oncology based upon tumor metabolism or immunologic phenotype: Technological pathways for point of care imaging and intervention.
Pogue BW, Paulsen KD, Samkoe KS, Elliott JT, Hasan T, Strong TV, Draney DR, Feldwisch J
Med Phys. 2016 Jun;43(6):3143-3156. doi: 10.1118/1.4951732.
PMID: 27277060