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Laura J. Tafe, MD

Title(s)
Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations
Assistant Director, Laboratory for Clinical Genomics and Advanced Technology (CGAT), Dartmouth-Hitchcock Medical Center

Department(s)
Pathology and Laboratory Medicine

Education
Medical School:
MD, Wayne State University School of Medicine, Detroit, MI, 2004

Residency:
Dartmouth-Hitchcock Medical Center, Lebanon, NH, Anatomic and Clinical Pathology, 2004-08

Fellowship:
Memorial Sloan-Kettering Cancer Center, New York, NY, Oncologic Pathology, 2008-09

Fellowship:
Memorial Sloan-Kettering Cancer Center, New York, NY, Diagnostic Molecular Pathology, 2009-10

Board Certification:
Anatomic and Clinical Pathology, 2008
Molecular Genetic Pathology, 2011

Websites
http://cancer.dartmouth.edu/lung_thoracic/teamprofile/56703/Laura_J_Tafe_MD

Contact Information

Department of Pathology
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon NH 03756


Selected Publications

 

The Utility of Comprehensive Sampling in Cervical Lymph Node Dissection for Head and Neck Squamous Cell Carcinoma: Is More Better?
Ould Ismail AA, Pettus JR, Tafe LJ, Black CC, Schutz SN, Pastel DA, Paydarfar JA, Kerr DA
Head Neck. 2026 Apr 23; doi: 10.1002/hed.70288. Epub 2026 Apr 23.
PMID: 42025582

Spindle Cell Rhabdomyosarcoma of Oral Cavity With TCF12::VGLL3 Fusion, Expanding on a Recently Described Entity With Digital Spatial Profiling and Long-Term Follow Up.
Dashti NK, Chakraborty D, Sadanandappa MK, Dehner CA, Zhang PJ, Paydarfar JA, Tafe LJ
Genes Chromosomes Cancer. 2026 Apr;65(4):e70126. doi: 10.1002/gcc.70126.
PMID: 41983910

Optical Genome Mapping Enhances Structural Variant Detection and Refines Risk Stratification in Chronic Lymphocytic Leukemia.
Chakraborty SR, Bickford MA, Smuliac NA, Tonseth KA, Bao J, Murad F, Dominguez Vigil IG, Steinmetz HB, Wainman LM, Shah P, Bengtson EM, PonnamReddy S, Harmon GA, Donnelly LL, Tafe LJ, Karrs JX, Kaur P, Khan WA
Genes (Basel). 2026 Jan 19;17(1) doi: 10.3390/genes17010106. Epub 2026 Jan 19.
PMID: 41595525

Predicting targeted therapy resistance in non-small cell lung cancer using multimodal machine learning.
Hua P, Olofson A, Farhadi F, Hondelink L, Tsongalis G, Dragnev K, Hoegemann Savellano D, Suriawinata A, Tafe L, Hassanpour S
J Thorac Dis. 2025 Oct 31;17(10):8700-8714. doi: 10.21037/jtd-2025-1012. Epub 2025 Oct 29.
PMID: 41229771

Clinical Implementation of Expanded Solid Tumor Fusion Detection With Whole-Transcriptome Sequencing at an Academic Cancer Center.
Hughes EG, Bergman DT, Green DC, Sukhadia SS, Lefferts JA, Karrs JX, Vyas RS, Cieslak Z, Barbuto JN, Ognjenovic NB, Palisoul BE, Tsongalis GJ, Tafe LJ, Shah PS
JCO Precis Oncol. 2025 May;9:e2400830. doi: 10.1200/PO-24-00830. Epub 2025 May 29.
PMID: 40440583

Clinicopathological and molecular characterization of non-small cell lung cancer with pericardial effusions.
Ma W, Rodrigues Simoes NJ, Seery PP, Li T, Tafe LJ, Kerr DA, Liu X
Cancer Cytopathol. 2025 May;133(5):e70015. doi: 10.1002/cncy.70015.
PMID: 40227522

Detection of Microsatellite Instability in Endometrial Carcinoma Using a Novel Homopolymer Assay.
Nicka CM, Green DC, Tsongalis GJ, Tafe LJ
Int J Surg Pathol. 2025 Sep;33(6):1341-1348. doi: 10.1177/10668969241311500. Epub 2025 Mar 3.
PMID: 40033864

Diagnostic next-generation sequencing to detect MYD88 L265P in Lymphoplasmacytic lymphoma compared to ddPCR.
Wainman LM, Huang G, Green DC, Tsongalis GJ, Tafe LJ, Khan WA, Kaur P, Shah PS, Karrs JX
Exp Mol Pathol. 2025 Mar;141:104956. doi: 10.1016/j.yexmp.2025.104956. Epub 2025 Feb 15.
PMID: 39954570

Celebrating 30 Years at the Heart of Precision Medicine.
Arcila ME, Bossler AD, Gibson J, Tafe LJ
J Mol Diagn. 2025 Jan;27(1):1-5. doi: 10.1016/j.jmoldx.2024.11.001.
PMID: 39722284

An Inflammatory Myofibroblastic Tumor With a Novel ALK(V1180L) Mutation Leading to Acquired Resistance to Tyrosine Kinase Inhibitors.
Sharpe B, Green DC, Tafe LJ, Wasp GT, Kerr DA, Dashti NK
Genes Chromosomes Cancer. 2024 Nov;63(11):e70012. doi: 10.1002/gcc.70012.
PMID: 39565115

View more publications on PubMed