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Joel A. Lefferts, PhD

Associate Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations
Assistant Director, Clinical Genomics and Advanced Technology Laboratory

Pathology and Laboratory Medicine

PhD, Rutgers Graduate School of Biomedical Sciences (University of Medicine & Dentistry of New Jersey), Newark, NJ , 2006

Molecular Pathology Fellowship, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 2006-2010

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Contact Information

Department of Pathology
One Medical Center Drive
Lebanon NH 03756

Phone: 603-650-8116
Email: Joel.A.Lefferts@hitchcock.org

Selected Publications


Y Chromosome: The Dark Matter of the Human Genome Unveiled.
Sathyanarayana SH, Sadanandappa MK, Lefferts JA
Clin Chem. 2024 Jun 3;70(6):887-888. doi: 10.1093/clinchem/hvae009.
PMID: 38825344

Shared chromosome 21q loss in a mixed subtype renal cell carcinoma: composite or collision tumor?
Stephen SA, Wainman LM, Lefferts JA, Pettus JR
Virchows Arch. 2024 May 23; doi: 10.1007/s00428-024-03820-w. Epub 2024 May 23.
PMID: 38780616

Analytical validation of a semi-automated methodology for quantitative measurement of SARS-CoV-2 RNA in wastewater collected in northern New England.
Robbins AA, Gallagher TL, Toledo DM, Hershberger KC, Salmela SM, Barney RE, Szczepiorkowski ZM, Tsongalis GJ, Martin IW, Hubbard JA, Lefferts JA
Microbiol Spectr. 2024 Jun 4;12(6):e0112223. doi: 10.1128/spectrum.01122-23. Epub 2024 May 15.
PMID: 38747589

Applications of Digital Polymerase Chain Reaction (dPCR) in Molecular and Clinical Testing.
Wainman LM, Sathyanarayana SH, Lefferts JA
J Appl Lab Med. 2024 Jan 3;9(1):124-137. doi: 10.1093/jalm/jfad103.
PMID: 38167753

Periductal Stromal Tumor of the Breast with a TERT Promoter Mutation: First Case Report with Comprehensive Molecular Analysis.
Anderson B, Marotti JD, Lefferts JA, Muller KE
Int J Surg Pathol. 2023 Dec;31(8):1626-1631. doi: 10.1177/10668969231157306. Epub 2023 Feb 23.
PMID: 36823780

Development and validation of a molecular tool to predict pathologic complete response in esophageal adenocarcinoma.
Qian DC, Lefferts JA, Zaki BI, Brickley EB, Jackson CR, Andrici J, Sriharan A, Lisovsky M
Dis Esophagus. 2022 Dec 14;35(12) doi: 10.1093/dote/doac035.
PMID: 35758407

Wastewater-Based SARS-CoV-2 Surveillance in Northern New England.
Toledo DM, Robbins AA, Gallagher TL, Hershberger KC, Barney RE, Salmela SM, Pilcher D, Cervinski MA, Nerenz RD, Szczepiorkowski ZM, Tsongalis GJ, Lefferts JA, Martin IW, Hubbard JA
Microbiol Spectr. 2022 Apr 27;10(2):e0220721. doi: 10.1128/spectrum.02207-21. Epub 2022 Apr 12.
PMID: 35412387

SNP-based chromosomal microarray characterization in a series of pure erythroid leukemia.
Mindiola Romero AE, Johnston MA, Giffin JT, Khan WA, Lefferts JA, Loo EY
Leuk Lymphoma. 2022 Aug;63(8):2009-2012. doi: 10.1080/10428194.2022.2057489. Epub 2022 Apr 3.
PMID: 35369841

A Rare Case of Low-Grade Dedifferentiated Liposarcoma Presenting as a Pharyngeal Polyp: Avoiding a Pitfall With Significant Repercussions.
Georgantzoglou N, Green D, Lefferts JA, Giannikaki L, Chliara E, Stavrianaki A, Kerr DA, Linos K
Int J Surg Pathol. 2022 Jun;30(4):405-412. doi: 10.1177/10668969211062859. Epub 2021 Dec 13.
PMID: 34894818

Squamous Cell Carcinoma in Hidradenitis Suppurativa Lesions Following Tumor Necrosis Factor α Inhibitors.
Cooper SD, Cowdrey MCE, Linos KD, Lefferts JA, Basic KK
Cutis. 2021 Apr;107(4):E5-E7. doi: 10.12788/cutis.0233.
PMID: 34096852

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