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Joel A. Lefferts, PhD

Title(s):
Associate Professor of Pathology and Laboratory Medicine

Additional Titles/Positions/Affiliations:
Assistant Director, Clinical Genomics and Advanced Technology Laboratory

Department(s):
Pathology and Laboratory Medicine

Education:
PhD, Rutgers Graduate School of Biomedical Sciences (University of Medicine & Dentistry of New Jersey), Newark, NJ , 2006

Molecular Pathology Fellowship, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 2006-2010

Contact Information:

Department of Pathology
One Medical Center Drive
Lebanon NH 03756

Phone: 603-650-8116
Email: Joel.A.Lefferts@hitchcock.org


Selected Publications:

 

Cross reactivity of NRASQ61R antibody in a subset of Spitz nevi with 11p gain: A potential confounding factor in the era of pathway-based diagnostic approach.
Parra O, Lefferts JA, Tafe LJ, Gru AA, Linos K
Hum Pathol. 2021 Feb 23; pii: S0046-8177(21)00026-5. doi: 10.1016/j.humpath.2021.02.001. Epub 2021 Feb 23.
PMID: 33636207

Rare Activating BRAF Alteration Involving the β3-αC Kinase Domain in Ganglioglioma.
Lin CC, Lefferts JA, Chan AM, Zanazzi G
J Neuropathol Exp Neurol. 2021 Feb 21; pii: nlab013. doi: 10.1093/jnen/nlab013. Epub 2021 Feb 21.
PMID: 33611593

Expanding Our Understanding of Nevogenesis: Copy Number Gain of Chromosome 15q in Melanocytic Nevi Is Associated With Distinct Histomorphologic Findings.
Olson LC, Lefferts JA, LeBlanc RE, Yan S, Momtahen S, Sriharan A, Linos K
Am J Surg Pathol. 2021 Jun 1;45(6):825-831. doi: 10.1097/PAS.0000000000001683.
PMID: 33577183

Implementation of Reverse Transcriptase PCR Testing for Severe Acute Respiratory Syndrome Coronavirus 2 under the US Food and Drug Administration Emergency Use Authorization.
Lefferts JA, Allen SF, Steinmetz HB, Tsongalis GJ
Clin Chem. 2021 Jan 30;67(2):434-435. doi: 10.1093/clinchem/hvaa278.
PMID: 33315063

Novel LRRFIP2-RAF1 fusion identified in an acral melanoma: A review of the literature on melanocytic proliferations with RAF1 fusions and the potential therapeutic implications.
LeBlanc RE, Lefferts JA, Baker ML, Linos KD
J Cutan Pathol. 2020 Dec;47(12):1181-1186. doi: 10.1111/cup.13817. Epub 2020 Sep 7.
PMID: 32700768

Concordance Analysis of the 23-Gene Expression Signature (myPath Melanoma) With Fluorescence In Situ Hybridization Assay and Single Nucleotide Polymorphism Array in the Analysis of Challenging Melanocytic Lesions: Results From an Academic Medical Center.
Castillo SA, Pham AK, Dagrosa AT, Yan S, Barton DT, Lefferts JA, Linos K
Am J Dermatopathol. 2020 Dec;42(12):939-947. doi: 10.1097/DAD.0000000000001713.
PMID: 32675469

Molecular genetic profiling reveals novel association between FLT3 mutation and survival in glioma.
Shee K, Chambers M, Hughes EG, Almiron DA, Deharvengt SJ, Green D, Lefferts JA, Andrew AS, Hickey WF, Tsongalis GJ
J Neurooncol. 2020 Jul;148(3):473-480. doi: 10.1007/s11060-020-03567-9. Epub 2020 Jun 24.
PMID: 32583303

Implementation of an Emergency Use Authorization Test During an Impending National Crisis.
Lefferts JA, Gutmann EJ, Martin IW, Wells WA, Tsongalis GJ
J Mol Diagn. 2020 Jul;22(7):844-846. doi: 10.1016/j.jmoldx.2020.05.001. Epub 2020 May 14.
PMID: 32417222

Lessons Learned from Direct-to-Consumer Genetic Testing.
Petersen LM, Lefferts JA
Clin Lab Med. 2020 Mar;40(1):83-92. doi: 10.1016/j.cll.2019.11.005. Epub 2020 Jan 7.
PMID: 32008642

CD10 and p63 expression in a sarcomatoid undifferentiated melanoma: A cautionary (and molecularly annotated) tale.
Lefferts JA, Loehrer AP, Yan S, Green DC, Deharvengt SJ, LeBlanc RE
J Cutan Pathol. 2020 Jun;47(6):541-547. doi: 10.1111/cup.13646. Epub 2020 Jan 20.
PMID: 31943331

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