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Alex H Gifford, MD

Associate Professor of Medicine
Associate Professor of The Dartmouth Institute

The Dartmouth Institute

Pennsylvania State University College of Medicine

Contact Information:

Section of Pulmonary and Critical Care Medicine, 5C
Dartmouth-Hitchcock Medical Center
Lebanon NH 03756

Phone: (603) 650-5533
Fax: (603) 650-0580
Email: alex.h.gifford@hitchcock.org

Professional Interests:

Characterizing biomarkers of disease activity, treatment response, and patterns of lung infection in cystic fibrosis (CF)

Investigating abnormalities in iron homeostasis in CF, including their contributions to anemia and chronic airway infection

Conduct of clinical trials in CF and non-CF bronchiectasis

Selected Publications:


  • May TL, Gifford AH, Lahiri T, Black A, Trang J, Cornell AG, Gonzalez K, Morin S, Napier M, Duarte CW, Zuckerman JB Complications of long and intermediate term venous catheters in cystic fibrosis patients: A multicenter study. J Cyst Fibros. 2017 Jun 1. pii: S1569-1993(17)30150-9 (view details on MedLine)

  • Gifford AH, Willger SD, Dolben EL, Moulton LA, Dorman DB, Bean H, Hill JE, Hampton TH, Ashare A, Hogan DA. The use of a multiplex transcript method for the analysis of the Pseudomonas aeruginosa gene expression profiles in the cystic fibrosis lung. Infect Immun 2016; 84: 2995-3006. (view details on MedLine)

  • Mahler DA, Gifford AH, Satti A, Jessop N, Eckert JH, D'Andrea P, Mota F, Banerjee R. Long-term safety of glycopyrrolate: A randomized study in patients with moderate-to-severe COPD (GEM3). Respir Med 2016; 115: 39-45. (view details on MedLine)

  • Gifford AH, Dorman DB, Moulton LA, Helm JE, Griffin MM, MacKenzie TA. Serum Iron Level Is Associated with Time to Antibiotics in Cystic Fibrosis. Clin Transl Sci 2015; 8(6): 754-758. (view details on MedLine)

  • Chang AS, Munson J, Gifford AH, Mahler DA. Prospective use of descriptors of dyspnea to diagnose common respiratory diseases. Chest 2015; 148(4): 895-902. (view details on MedLine)

  • MacKenzie T, Gifford AH, Sabadosa KA, Quinton HB, Knapp EA, Goss CH, Marshall BC Longevity of patients with cystic fibrosis in 2000 to 2010 and beyond: survival analysis of the Cystic Fibrosis Foundation patient registry. Ann Intern Med 2014; 161(4): 233-41. (view details on MedLine)

  • Gifford AH, Alexandru DM, Li Z, Dorman DB, Moulton LA, Price KE, Hampton TH, Sogin ML, Zuckerman JB, Parker HW, Stanton BA, O'Toole GA Iron supplementation does not worsen respiratory health or alter the sputum microbiome in cystic fibrosis. J Cyst Fibros 2014; 13(3): 311-8. (view details on MedLine)

  • Gifford AH, Moulton LA, Dorman DB, Olbina G, Westerman M, Parker HW, Stanton BA, O'Toole GA Iron homeostasis during cystic fibrosis pulmonary exacerbation. Clin Transl Sci 2012; 5(4): 368-73. (view details on MedLine)

  • Filkins LM, Hampton TH, Gifford AH, Gross MJ, Hogan DA, Sogin ML, Morrison HG, Paster BJ, O'Toole GA Prevalence of streptococci and increased polymicrobial diversity associated with cystic fibrosis patient stability. J Bacteriol 2012; 194(17): 4709-17. (view details on MedLine)

  • Gifford AH, Miller SD, Jackson BP, Hampton TH, O'Toole GA, Stanton BA, Parker HW Iron and CF-related anemia: expanding clinical and biochemical relationships. Pediatr Pulmonol 2011; 46(2): 160-5. (view details on MedLine)