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Alex H Gifford, MD

Associate Professor of Medicine
Associate Professor of The Dartmouth Institute

Additional Titles/Positions/Affiliations:
Director, Adult Cystic Fibrosis Program

The Dartmouth Institute

Pennsylvania State University College of Medicine

Contact Information:

Section of Pulmonary and Critical Care Medicine, 5C
Dartmouth-Hitchcock Medical Center
Lebanon NH 03756

Phone: (603) 650-5533
Fax: (603) 640-1911

Professional Interests:

Characterizing biomarkers of disease activity, treatment response, and patterns of lung infection in cystic fibrosis (CF)

Investigating abnormalities in iron homeostasis in CF, including their contributions to anemia and chronic airway infection

Conduct of clinical trials in CF and non-CF bronchiectasis

Selected Publications:


  • Garlow GM, Gettle LS, Felicetti NJ, Polineni D, Gifford AH. Perspectives on anemia and iron deficiency from the cystic fibrosis care community. Pediatr Pulmonol. 2019 Mar 28. doi: 10.1002/ppul.24323. [Epub ahead of print] (view details in PubMed)

  • Gifford AH, Heltshe SL, Goss CH. CFTR Modulator Use Is Associated with Higher Hemoglobin Levels in Individuals with Cystic Fibrosis. Ann Am Thorac Soc 2019; 16: 331-340 (view details in PubMed)

  • May TL, Gifford AH, Lahiri T, Black A, Trang J, Cornell AG, Gonzalez K, Morin S, Napier M, Duarte CW, Zuckerman JB Complications of long and intermediate term venous catheters in cystic fibrosis patients: A multicenter study. J Cyst Fibros 2018; 17: 96-104. (view details in PubMed)

  • Skopelja S, Hamilton BJ, Jones JD, Yang ML, Mamula M, Ashare A, Gifford AH, Rigby WF The role for neutrophil extracellular traps in cystic fibrosis autoimmunity. JCI Insight 2016; 1: e88912. (view details in PubMed)

  • Gifford AH, Willger SD, Dolben EL, Moulton LA, Dorman DB, Bean H, Hill JE, Hampton TH, Ashare A, Hogan DA. The use of a multiplex transcript method for the analysis of the Pseudomonas aeruginosa gene expression profiles in the cystic fibrosis lung. Infect Immun 2016; 84: 2995-3006. (view details in PubMed)

  • Gifford AH, Dorman DB, Moulton LA, Helm JE, Griffin MM, MacKenzie TA. Serum Iron Level Is Associated with Time to Antibiotics in Cystic Fibrosis. Clin Transl Sci 2015; 8(6): 754-758. (view details in PubMed)

  • MacKenzie T, Gifford AH, Sabadosa KA, Quinton HB, Knapp EA, Goss CH, Marshall BC Longevity of patients with cystic fibrosis in 2000 to 2010 and beyond: survival analysis of the Cystic Fibrosis Foundation patient registry. Ann Intern Med 2014; 161(4): 233-41. (view details in PubMed)

  • Gifford AH, Alexandru DM, Li Z, Dorman DB, Moulton LA, Price KE, Hampton TH, Sogin ML, Zuckerman JB, Parker HW, Stanton BA, O'Toole GA Iron supplementation does not worsen respiratory health or alter the sputum microbiome in cystic fibrosis. J Cyst Fibros 2014; 13(3): 311-8. (view details in PubMed)

  • Gifford AH, Moulton LA, Dorman DB, Olbina G, Westerman M, Parker HW, Stanton BA, O'Toole GA Iron homeostasis during cystic fibrosis pulmonary exacerbation. Clin Transl Sci 2012; 5(4): 368-73. (view details in PubMed)

  • Gifford AH, Miller SD, Jackson BP, Hampton TH, O'Toole GA, Stanton BA, Parker HW Iron and CF-related anemia: expanding clinical and biochemical relationships. Pediatr Pulmonol 2011; 46(2): 160-5. (view details in PubMed)