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Ruth I. Connor, PhD

Title(s)
Associate Professor of Pediatrics
Associate Professor of Microbiology and Immunology

Department(s)
Pediatrics
Microbiology and Immunology

Education
Ohio State University
1988

Programs
Immunology Program

Websites
http://www.dms.dartmouth.edu/microbio/
http://www.dms.dartmouth.edu/immuno/
http://www.dms.dartmouth.edu/faculty/

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Contact Information

Department of Microbiology and Immunology
HB 7556
Dartmouth-Hitchcock Medical Center
Lebanon NH 03756

Phone: 603-650-8833
Email: Ruth.I.Connor@Dartmouth.edu


Selected Publications

 

Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages.
Chernyshev M, Sakharkar M, Connor RI, Dugan HL, Sheward DJ, Rappazzo CG, Stalmarck A, Forsell MNE, Wright PF, Corcoran M, Murrell B, Walker LM, Karlsson Hedestam GB
Nat Commun. 2023 Apr 19;14(1):2249. doi: 10.1038/s41467-023-37972-1. Epub 2023 Apr 19.
PMID: 37076511

Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike.
Crowley AR, Natarajan H, Hederman AP, Bobak CA, Weiner JA, Wieland-Alter W, Lee J, Bloch EM, Tobian AAR, Redd AD, Blankson JN, Wolf D, Goetghebuer T, Marchant A, Connor RI, Wright PF, Ackerman ME
Elife. 2022 Mar 15;11 doi: 10.7554/eLife.75228. Epub 2022 Mar 15.
PMID: 35289271

Longitudinal Systemic and Mucosal Immune Responses to SARS-CoV-2 Infection.
Wright PF, Prevost-Reilly AC, Natarajan H, Brickley EB, Connor RI, Wieland-Alter WF, Miele AS, Weiner JA, Nerenz RD, Ackerman ME
J Infect Dis. 2022 Sep 28;226(7):1204-1214. doi: 10.1093/infdis/jiac065.
PMID: 35188974

Antibody attributes that predict the neutralization and effector function of polyclonal responses to SARS-CoV-2.
Natarajan H, Xu S, Crowley AR, Butler SE, Weiner JA, Bloch EM, Littlefield K, Benner SE, Shrestha R, Ajayi O, Wieland-Alter W, Sullivan D, Shoham S, Quinn TC, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Connor RI, Wright PF, Ackerman ME
BMC Immunol. 2022 Feb 16;23(1):7. doi: 10.1186/s12865-022-00480-w. Epub 2022 Feb 16.
PMID: 35172720

Boosting of Cross-Reactive Antibodies to Endemic Coronaviruses by SARS-CoV-2 Infection but not Vaccination with Stabilized Spike.
Crowley AR, Natarajan H, Hederman AP, Bobak CA, Weiner JA, Wieland-Alter W, Lee J, Bloch EM, Tobian AAR, Redd AD, Blankson JN, Wolf D, Goetghebuer T, Marchant A, Connor RI, Wright PF, Ackerman ME
medRxiv. 2021 Oct 28; pii: 2021.10.27.21265574. doi: 10.1101/2021.10.27.21265574. Epub 2021 Oct 28.
PMID: 34729565

Antibody Attributes that Predict the Neutralization and Effector Function of Polyclonal Responses to SARS-CoV-2.
Natarajan H, Xu S, Crowley AR, Butler SE, Weiner JA, Bloch EM, Littlefield K, Benner SE, Shrestha R, Ajayi O, Wieland-Alter W, Sullivan D, Shoham S, Quinn TC, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Connor RI, Wright PF, Ackerman ME
medRxiv. 2021 Aug 8; pii: 2021.08.06.21261710. doi: 10.1101/2021.08.06.21261710. Epub 2021 Aug 8.
PMID: 34401890

Mucosal immunity to poliovirus.
Connor RI, Brickley EB, Wieland-Alter WF, Ackerman ME, Weiner JA, Modlin JF, Bandyopadhyay AS, Wright PF
Mucosal Immunol. 2022 Jan;15(1):1-9. doi: 10.1038/s41385-021-00428-0. Epub 2021 Jul 8.
PMID: 34239028

Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma.
Natarajan H, Crowley AR, Butler SE, Xu S, Weiner JA, Bloch EM, Littlefield K, Wieland-Alter W, Connor RI, Wright PF, Benner SE, Bonny TS, Laeyendecker O, Sullivan D, Shoham S, Quinn TC, Larman HB, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Ackerman ME
mBio. 2021 Apr 20;12(2) doi: 10.1128/mBio.00765-21. Epub 2021 Apr 20.
PMID: 33879585

Prolonged evolution of the human B cell response to SARS-CoV-2 infection.
Sakharkar M, Rappazzo CG, Wieland-Alter WF, Hsieh CL, Wrapp D, Esterman ES, Kaku CI, Wec AZ, Geoghegan JC, McLellan JS, Connor RI, Wright PF, Walker LM
Sci Immunol. 2021 Feb 23;6(56) doi: 10.1126/sciimmunol.abg6916.
PMID: 33622975

Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals.
Butler SE, Crowley AR, Natarajan H, Xu S, Weiner JA, Bobak CA, Mattox DE, Lee J, Wieland-Alter W, Connor RI, Wright PF, Ackerman ME
Front Immunol. 2020;11:618685. doi: 10.3389/fimmu.2020.618685. Epub 2021 Jan 28.
PMID: 33584712

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