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Elizabeth L. Barry, PhD

Title(s):
Associate Professor of Epidemiology
Associate Professor of Community and Family Medicine

Department(s):
Epidemiology
Community and Family Medicine

Education:
Dartmouth College CECS, MS 2003

University of Wisconsin-Madison, PhD 1989

Grinnell College, BA 1983

Websites:
https://geiselmed.dartmouth.edu/epidemiology/people/faculty/elizabeth-barry/

http://www.clinicaltrials.gov/ct/gui/show/NCT00153816

Contact Information:

One Medical Center Drive
Rubin Building, Room 857
HB 7927
Lebanon NH 03756

Office: Room 857
Phone: 603-653-9932
Email: elizabeth.l.barry@dartmouth.edu


Professional Interests:

Dr. Barry's current research focuses on the chemoprevention of cancer and the pharmacogenetics of chemopreventative agents. She is especially interested in the role and mechanism of action of anti-inflammatory drugs (such as aspirin) and nutritional supplements (such as calcium, vitamin D and folate) as chemopreventative agents for cancer. Using data from clinical trials, Dr. Barry is currently investigating how genetic polymorphisms may modify the effectiveness of some of these drugs in the prevention of colorectal adenomas. In addition to her interest in cancer, Dr. Barry has a long-standing interest in calcium and vitamin D regulation and their role in bone health and disease (osteoporosis).

Courses Taught:

Medical Pharmacology (Calcium and Bone Pharmacology)


Selected Publications:

 

Body Composition and Aspirin Dose for Colorectal Adenoma Prevention in a Randomized Clinical Trial.
Passarelli MN, Barry EL, Rees JR, Mott LA, Ahnen DJ, Baron JA
Cancer Epidemiol Biomarkers Prev. 2019 Jul;28(7):1262-1265. doi: 10.1158/1055-9965.EPI-19-0205.
PMID: 31263057

Vitamin D as Cancer Therapy?: Insights From 2 New Trials.
Barry EL, Passarelli MN, Baron JA
JAMA. 2019 Apr 9;321(14):1354-1355. doi: 10.1001/jama.2019.2589.
PMID: 30964513

Effects of supplemental calcium and vitamin D on tight-junction proteins and mucin-12 expression in the normal rectal mucosa of colorectal adenoma patients.
Mandle HB, Jahan FA, Bostick RM, Baron JA, Barry EL, Yacoub R, Merrill J, Rutherford RE, Seabrook ME, Fedirko V
Mol Carcinog. 2019 Jul;58(7):1279-1290. doi: 10.1002/mc.23010. Epub 2019 Apr 2.
PMID: 30938860

No Evidence for Posttreatment Effects of Vitamin D and Calcium Supplementation on Risk of Colorectal Adenomas in a Randomized Trial.
Calderwood AH, Baron JA, Mott LA, Ahnen DJ, Bostick RM, Figueiredo JC, Passarelli MN, Rees JR, Robertson DJ, Barry EL
Cancer Prev Res (Phila). 2019 May;12(5):295-304. doi: 10.1158/1940-6207.CAPR-19-0023. Epub 2019 Mar 4.
PMID: 30833381

Effects of supplemental vitamin D and calcium on markers of proliferation, differentiation, and apoptosis in the normal colorectal mucosa of colorectal adenoma patients.
Gao Y, Um CY, Fedirko V, Rutherford RE, Seabrook ME, Barry EL, Baron JA, Bostick RM
PLoS One. 2018;13(12):e0208762. doi: 10.1371/journal.pone.0208762. Epub 2018 Dec 17.
PMID: 30557404

Effects of vitamin D and calcium on expression of MSH2 and transforming growth factors in normal-appearing colorectal mucosa of sporadic colorectal adenoma patients: A randomized clinical trial.
Kwan AK, Um CY, Rutherford RE, Seabrook ME, Barry EL, Fedirko V, Baron JA, Bostick RM
Mol Carcinog. 2019 Apr;58(4):511-523. doi: 10.1002/mc.22945. Epub 2018 Dec 21.
PMID: 30499618

NSAIDs and Colorectal Cancer Phenotypes: What Now?
Barry EL, Fedirko V, Baron JA
J Natl Cancer Inst. 2019 May 1;111(5):440-441. doi: 10.1093/jnci/djy174.
PMID: 30388268

Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients.
Hodge R, Mandle HB, Ray S, Tandon S, Peterson M, Henry A, Jahan FA, Bostick RM, Baron JA, Barry EL, Yacoub R, Rutherford RE, Seabrook ME, Fedirko V
Cancer Prev Res (Phila). 2018 Nov;11(11):707-716. doi: 10.1158/1940-6207.CAPR-18-0123. Epub 2018 Sep 12.
PMID: 30209117

Body mass index, calcium supplementation and risk of colorectal adenomas.
Barry EL, Lund JL, Westreich D, Mott LA, Ahnen DJ, Beck GJ, Bostick RM, Bresalier RS, Burke CA, Church TR, Rees JR, Robertson DJ, Baron JA
Int J Cancer. 2019 Feb 1;144(3):448-458. doi: 10.1002/ijc.31803. Epub 2018 Oct 30.
PMID: 30117164

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
Schmit SL, Edlund CK, Schumacher FR, Gong J, Harrison TA, Huyghe JR, Qu C, Melas M, Van Den Berg DJ, Wang H, Tring S, Plummer SJ, Albanes D, Alonso MH, Amos CI, Anton K, Aragaki AK, Arndt V, Barry EL, Berndt SI, Bezieau S, Bien S, Bloomer A, Boehm J, Boutron-Ruault MC, Brenner H, Brezina S, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Castelao JE, Chan AT, Chang-Claude J, Chanock SJ, Cheng I, Cheng YW, Chin LS, Church JM, Church T, Coetzee GA, Cotterchio M, Cruz Correa M, Curtis KR, Duggan D, Easton DF, English D, Feskens EJM, Fischer R, FitzGerald LM, Fortini BK, Fritsche LG, Fuchs CS, Gago-Dominguez M, Gala M, Gallinger SJ, Gauderman WJ, Giles GG, Giovannucci EL, Gogarten SM, Gonzalez-Villalpando C, Gonzalez-Villalpando EM, Grady WM, Greenson JK, Gsur A, Gunter M, Haiman CA, Hampe J, Harlid S, Harju JF, Hayes RB, Hofer P, Hoffmeister M, Hopper JL, Huang SC, Huerta JM, Hudson TJ, Hunter DJ, Idos GE, Iwasaki M, Jackson RD, Jacobs EJ, Jee SH, Jenkins MA, Jia WH, Jiao S, Joshi AD, Kolonel LN, Kono S, Kooperberg C, Krogh V, Kuehn T, Kury S, LaCroix A, Laurie CA, Lejbkowicz F, Lemire M, Lenz HJ, Levine D, Li CI, Li L, Lieb W, Lin Y, Lindor NM, Liu YR, Loupakis F, Lu Y, Luh F, Ma J, Mancao C, Manion FJ, Markowitz SD, Martin V, Matsuda K, Matsuo K, McDonnell KJ, McNeil CE, Milne R, Molina AJ, Mukherjee B, Murphy N, Newcomb PA, Offit K, Omichessan H, Palli D, Cotore JPP, Perez-Mayoral J, Pharoah PD, Potter JD, Qu C, Raskin L, Rennert G, Rennert HS, Riggs BM, Schafmayer C, Schoen RE, Sellers TA, Seminara D, Severi G, Shi W, Shibata D, Shu XO, Siegel EM, Slattery ML, Southey M, Stadler ZK, Stern MC, Stintzing S, Taverna D, Thibodeau SN, Thomas DC, Trichopoulou A, Tsugane S, Ulrich CM, van Duijnhoven FJB, van Guelpan B, Vijai J, Virtamo J, Weinstein SJ, White E, Win AK, Wolk A, Woods M, Wu AH, Wu K, Xiang YB, Yen Y, Zanke BW, Zeng YX, Zhang B, Zubair N, Kweon SS, Figueiredo JC, Zheng W, Marchand LL, Lindblom A, Moreno V, Peters U, Casey G, Hsu L, Conti DV, Gruber SB
J Natl Cancer Inst. 2019 Feb 1;111(2):146-157. doi: 10.1093/jnci/djy099.
PMID: 29917119

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