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Elizabeth L. Barry, PhD

Title(s):
Associate Professor of Epidemiology
Associate Professor of Community and Family Medicine

Department(s):
Epidemiology
Community and Family Medicine

Education:
Dartmouth College CECS, MS
University of Wisconsin-Madison, PhD
Grinnell College, BA

Programs:
Norris Cotton Cancer Center
Quantitative Biomedical Sciences

Websites:
https://geiselmed.dartmouth.edu/epidemiology/people/faculty/elizabeth-barry/

http://www.clinicaltrials.gov/ct/gui/show/NCT00153816

Contact Information:

One Medical Center Drive
Rubin Building, Room 857
HB 7927
Lebanon NH 03756

Office: Room 857
Phone: 603-653-9932
Email: elizabeth.l.barry@dartmouth.edu


Professional Interests:

Dr. Barry's current research focuses on the chemoprevention of cancer and the pharmacogenetics of chemopreventative agents. She is especially interested in the role and mechanism of action of anti-inflammatory drugs (such as aspirin) and nutritional supplements (such as calcium, vitamin D and folate) as chemopreventative agents for cancer. Using data from clinical trials, Dr. Barry is currently investigating how genetic polymorphisms may modify the effectiveness of some of these drugs in the prevention of colorectal adenomas. In addition to her interest in cancer, Dr. Barry has a long-standing interest in calcium and vitamin D regulation and their role in bone health and disease (osteoporosis).

Courses Taught:

Medical Pharmacology (Calcium and Bone Pharmacology)


Selected Publications:

 

Circulating 27-hydroxycholesterol and Risk of Colorectal Adenomas and Serrated Polyps.
Passarelli MN, Thompson BM, McDonald JG, Snover DC, Palys TJ, Rees JR, Barry EL, Baron JA
Cancer Prev Res (Phila). 2021 Apr;14(4):479-488. doi: 10.1158/1940-6207.CAPR-20-0414. Epub 2021 Jan 6.
PMID: 33408073

Effects of Supplemental Calcium and Vitamin D on Circulating Biomarkers of Gut Barrier Function in Patients with Colon Adenoma: A Randomized Clinical Trial.
Vermandere K, Bostick RM, Tran HQ, Gewirtz AT, Barry EL, Rutherford RE, Seabrook ME, Fedirko V
Cancer Prev Res (Phila). 2020 Nov 23; doi: 10.1158/1940-6207.CAPR-20-0461. Epub 2020 Nov 23.
PMID: 33229339

Risk of keratinocyte carcinomas with vitamin D and calcium supplementation: a secondary analysis of a randomized clinical trial.
Passarelli MN, Karagas MR, Mott LA, Rees JR, Barry EL, Baron JA
Am J Clin Nutr. 2020 Dec 10;112(6):1532-1539. doi: 10.1093/ajcn/nqaa267.
PMID: 33022713

Inflammation Modulation by Vitamin D and Calcium in the Morphologically Normal Colorectal Mucosa of Patients with Colorectal Adenoma in a Clinical Trial.
Gibbs DC, Fedirko V, Baron JA, Barry EL, Flanders WD, McCullough ML, Yacoub R, Raavi T, Rutherford RE, Seabrook ME, Bostick RM
Cancer Prev Res (Phila). 2020 Sep 11; doi: 10.1158/1940-6207.CAPR-20-0140. Epub 2020 Sep 11.
PMID: 32917645

Metabolomics Analysis of Aspirin's Effects in Human Colon Tissue and Associations with Adenoma Risk.
Barry EL, Fedirko V, Uppal K, Ma C, Liu K, Mott LA, Peacock JL, Passarelli MN, Baron JA, Jones DP
Cancer Prev Res (Phila). 2020 Oct;13(10):863-876. doi: 10.1158/1940-6207.CAPR-20-0014. Epub 2020 Jul 12.
PMID: 32655007

Evaluation of a Deep Neural Network for Automated Classification of Colorectal Polyps on Histopathologic Slides.
Wei JW, Suriawinata AA, Vaickus LJ, Ren B, Liu X, Lisovsky M, Tomita N, Abdollahi B, Kim AS, Snover DC, Baron JA, Barry EL, Hassanpour S
JAMA Netw Open. 2020 Apr 1;3(4):e203398. doi: 10.1001/jamanetworkopen.2020.3398. Epub 2020 Apr 1.
PMID: 32324237

Folic acid supplementation and risk of colorectal neoplasia during long-term follow-up of a randomized clinical trial.
Passarelli MN, Barry EL, Rees JR, Mott LA, Zhang D, Ahnen DJ, Bresalier RS, Haile RW, McKeown-Eyssen G, Snover DC, Cole BF, Baron JA
Am J Clin Nutr. 2019 Oct 1;110(4):903-911. doi: 10.1093/ajcn/nqz160.
PMID: 31401653

Body Composition and Aspirin Dose for Colorectal Adenoma Prevention in a Randomized Clinical Trial.
Passarelli MN, Barry EL, Rees JR, Mott LA, Ahnen DJ, Baron JA
Cancer Epidemiol Biomarkers Prev. 2019 Jul;28(7):1262-1265. doi: 10.1158/1055-9965.EPI-19-0205.
PMID: 31263057

Vitamin D as Cancer Therapy?: Insights From 2 New Trials.
Barry EL, Passarelli MN, Baron JA
JAMA. 2019 Apr 9;321(14):1354-1355. doi: 10.1001/jama.2019.2589.
PMID: 30964513

Effects of supplemental calcium and vitamin D on tight-junction proteins and mucin-12 expression in the normal rectal mucosa of colorectal adenoma patients.
Mandle HB, Jahan FA, Bostick RM, Baron JA, Barry EL, Yacoub R, Merrill J, Rutherford RE, Seabrook ME, Fedirko V
Mol Carcinog. 2019 Jul;58(7):1279-1290. doi: 10.1002/mc.23010. Epub 2019 Apr 2.
PMID: 30938860

View more publications on PubMed