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Elizabeth L. Barry, PhD

Title(s):
Associate Professor of Epidemiology
Associate Professor of Community and Family Medicine

Department(s):
Epidemiology
Community and Family Medicine

Education:
Dartmouth College CECS, MS 2003

University of Wisconsin-Madison, PhD 1989

Grinnell College, BA 1983

Websites:
https://geiselmed.dartmouth.edu/epidemiology/people/faculty/elizabeth-barry/

http://www.clinicaltrials.gov/ct/gui/show/NCT00153816

Contact Information:

One Medical Center Drive
Rubin Building, Room 857
HB 7927
Lebanon NH 03756

Office: Room 857
Phone: 603-653-9932
Email: elizabeth.l.barry@dartmouth.edu


Professional Interests:

Dr. Barry's current research focuses on the chemoprevention of cancer and the pharmacogenetics of chemopreventative agents. She is especially interested in the role and mechanism of action of anti-inflammatory drugs (such as aspirin) and nutritional supplements (such as calcium, vitamin D and folate) as chemopreventative agents for cancer. Using data from clinical trials, Dr. Barry is currently investigating how genetic polymorphisms may modify the effectiveness of some of these drugs in the prevention of colorectal adenomas. In addition to her interest in cancer, Dr. Barry has a long-standing interest in calcium and vitamin D regulation and their role in bone health and disease (osteoporosis).

Courses Taught:

Medical Pharmacology (Calcium and Bone Pharmacology)


Selected Publications:

 

Can the Sum of Adenoma Diameters (Adenoma Bulk) on Index Examination Predict Risk of Metachronous Advanced Neoplasia?
Anderson JC, Morris CB, Robertson DJ, Barry ELR, Figueiredo JC, Cruz-Correa M, Bostick RM, Ahnen DJ, Baron JA
J Clin Gastroenterol. 2017 Aug 1; doi: 10.1097/MCG.0000000000000899. Epub 2017 Aug 1.
PMID: 28767463

Unmetabolized Folic Acid, Tetrahydrofolate, and Colorectal Adenoma Risk.
Rees JR, Morris CB, Peacock JL, Ueland PM, Barry EL, McKeown-Eyssen GE, Figueiredo JC, Snover DC, Baron JA
Cancer Prev Res (Phila). 2017 Aug;10(8):451-458. doi: 10.1158/1940-6207.CAPR-16-0278. Epub 2017 Jun 9.
PMID: 28600398

Factors Associated With Shorter Colonoscopy Surveillance Intervals for Patients With Low-Risk Colorectal Adenomas and Effects on Outcome.
Anderson JC, Baron JA, Ahnen DJ, Barry EL, Bostick RM, Burke CA, Bresalier RS, Church TR, Cole BF, Cruz-Correa M, Kim AS, Mott LA, Sandler RS, Robertson DJ
Gastroenterology. 2017 Jun;152(8):1933-1943.e5. doi: 10.1053/j.gastro.2017.02.010. Epub 2017 Feb 20.
PMID: 28219690

Plasma lipoxin A<sub>4</sub> and resolvin D1 are not associated with reduced adenoma risk in a randomized trial of aspirin to prevent colon adenomas.
Fedirko V, McKeown-Eyssen G, Serhan CN, Barry EL, Sandler RS, Figueiredo JC, Ahnen DJ, Bresalier RS, Robertson DJ, Anderson CW, Baron JA
Mol Carcinog. 2017 Aug;56(8):1977-1983. doi: 10.1002/mc.22629. Epub 2017 Mar 6.
PMID: 28218420

Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial.
Barry EL, Peacock JL, Rees JR, Bostick RM, Robertson DJ, Bresalier RS, Baron JA
JAMA Oncol. 2017 May 1;3(5):628-635. doi: 10.1001/jamaoncol.2016.5917.
PMID: 27978548

Lifestyle and Other Factors Explain One-Half of the Variability in the Serum 25-Hydroxyvitamin D Response to Cholecalciferol Supplementation in Healthy Adults.
Rees JR, Mott LA, Barry EL, Baron JA, Bostick RM, Figueiredo JC, Bresalier RS, Robertson DJ, Peacock JL
J Nutr. 2016 Nov;146(11):2312-2324. Epub 2016 Sep 28.
PMID: 27683872

Randomized controlled trials: who fails run-in?
Rees JR, Mott LA, Barry EL, Baron JA, Figueiredo JC, Robertson DJ, Bresalier RS, Peacock JL
Trials. 2016 Jul 29;17:374. doi: 10.1186/s13063-016-1451-9. Epub 2016 Jul 29.
PMID: 27474021

Effects of supplemental calcium and vitamin D on the APC/β-catenin pathway in the normal colorectal mucosa of colorectal adenoma patients.
Liu S, Barry EL, Baron JA, Rutherford RE, Seabrook ME, Bostick RM
Mol Carcinog. 2017 Feb;56(2):412-424. doi: 10.1002/mc.22504. Epub 2016 Jun 14.
PMID: 27254743

Association between adenoma location and risk of recurrence.
Pohl H, Robertson DJ, Mott LA, Ahnen DJ, Burke CA, Barry EL, Bresalier RS, Figueiredo JC, Shaukat A, Sandler RS, Baron JA
Gastrointest Endosc. 2016 Oct;84(4):709-16. doi: 10.1016/j.gie.2016.02.048. Epub 2016 Mar 11.
PMID: 26975233

Calcium and Vitamin D for the Prevention of Colorectal Adenomas.
Baron JA, Barry EL, Ivanova A
N Engl J Med. 2016 Feb 25;374(8):791-2. doi: 10.1056/NEJMc1514501.
PMID: 26933859