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Brent L Berwin, PhD

Title(s):
Associate Professor of Microbiology and Immunology

Department(s):
Microbiology and Immunology

Education:
University of Wisconsin-Madison, Ph.D., 1999
Lewis & Clark College, B.S., 1991

Dr. Berwin graduated from the University of Wisconsin-Madison in 1999. He did his postdoc training at Duke University and joined Dartmouth Medical School in the fall of 2004. Dr. Berwin is an Associate Professor in the Department of Microbiology and Immunology.

Programs:
Immunology Program
Molecular and Cellular Biology Graduate Programs
Norris Cotton Cancer Center

Websites:
http://dms.dartmouth.edu/microbio/
http://dms.dartmouth.edu/immuno/
http://www.dartmouth.edu/~immuno-cobre/

Contact Information:

Dartmouth Medical Center
1 Medical Center Dr.
HB 7556 - Rm. 614W
Lebanon NH 03756

Phone: 603-650-6899
Fax: 603-650-6223
Email: berwin@dartmouth.edu


Selected Publications:

 

A Syngeneic Mouse Model of Epithelial Ovarian Cancer Port Site Metastases.
Wilkinson-Ryan I, Pham MM, Sergent P, Tafe LJ, Berwin BL
Transl Oncol. 2018 Sep 26;12(1):62-68. doi: 10.1016/j.tranon.2018.08.020. Epub 2018 Sep 26.
PMID: 30268949

Inflammasomes: An emerging mechanism translating environmental toxicant exposure into neuroinflammation in Parkinson's disease.
Anderson FL, Coffey MM, Berwin BL, Havrda MC
Toxicol Sci. 2018 Sep 7; doi: 10.1093/toxsci/kfy219. Epub 2018 Sep 7.
PMID: 30203060

Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative <i>Pseudomonas aeruginosa</i>.
Balakrishnan A, Karki R, Berwin B, Yamamoto M, Kanneganti TD
Cell Death Discov. 2018;5:3. doi: 10.1038/s41420-018-0068-z. Epub 2018 Jun 27.
PMID: 30062052

Phosphatidylinositol-(3,4,5)-Trisphosphate Induces Phagocytosis of Nonmotile Pseudomonas aeruginosa.
Demirdjian S, Hopkins D, Sanchez H, Libre M, Gerber SA, Berwin B
Infect Immun. 2018 Aug;86(8) pii: e00215-18. doi: 10.1128/IAI.00215-18. Epub 2018 Jul 23.
PMID: 29844235

Evaluating blood clot progression using magnetic particle spectroscopy.
Khurshid H, Shi Y, Berwin BL, Weaver JB
Med Phys. 2018 Jul;45(7):3258-3263. doi: 10.1002/mp.12983. Epub 2018 Jun 3.
PMID: 29772078

Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa.
Barnaby R, Koeppen K, Nymon A, Hampton TH, Berwin B, Ashare A, Stanton BA
Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L432-L438. doi: 10.1152/ajplung.00461.2017. Epub 2017 Nov 16.
PMID: 29146575

The effect of loss of O-antigen ligase on phagocytic susceptibility of motile and non-motile Pseudomonas aeruginosa.
Demirdjian S, Schutz K, Wargo MJ, Lam JS, Berwin B
Mol Immunol. 2017 Dec;92:106-115. doi: 10.1016/j.molimm.2017.10.015. Epub 2017 Oct 20.
PMID: 29059582

Acidosis exacerbates in vivo IL-1-dependent inflammatory responses and neutrophil recruitment during pulmonary Pseudomonas aeruginosa infection.
Torres IM, Patankar YR, Berwin B
Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L225-L235. doi: 10.1152/ajplung.00338.2017. Epub 2017 Oct 6.
PMID: 28982735

Editor's Highlight: Nlrp3 Is Required for Inflammatory Changes and Nigral Cell Loss Resulting From Chronic Intragastric Rotenone Exposure in Mice.
Martinez EM, Young AL, Patankar YR, Berwin BL, Wang L, von Herrmann KM, Weier JM, Havrda MC
Toxicol Sci. 2017 Sep 1;159(1):64-75. doi: 10.1093/toxsci/kfx117.
PMID: 28903492

Acidosis increases the susceptibility of respiratory epithelial cells to <i>Pseudomonas aeruginosa</i>-induced cytotoxicity.
Torres IM, Demirdjian S, Vargas J, Goodale BC, Berwin B
Am J Physiol Lung Cell Mol Physiol. 2017 Jul 1;313(1):L126-L137. doi: 10.1152/ajplung.00524.2016. Epub 2017 Apr 6.
PMID: 28385813