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Benjamin B Williams, PhD

Title(s)
Professor of Medicine
Professor of Radiology

Additional Titles/Positions/Affiliations
Adjunct Associate Professor of Engineering, Thayer School of Engineering
Chief of Clinical Physics, Dartmouth-Hitchcock Medical Center

Department(s)
Medicine
Radiology

Education
Kenyon College, Gambier, OH. B.A., Physics, 1995
University of Chicago, Chicago, IL. Ph.D., Medical Physics, 2003

Programs
Dartmouth Cancer Center

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Contact Information

Radiation Oncology
Dartmouth Hitchcok Medical Center
1 Medical Center Dr.
Lebanon NH 03756

Office: DHMC, Radiation Oncology, 263L3
Phone: 603-650-5239
Email: Ben.Williams@Dartmouth.edu

Professional Interests

Tissue oxygen measurement, Small animal imaging, Image reconstruction, Biodosimetry

Grant Information

NIH NCI P01 CA190193. Mar 2015 – Mar 2020. Clinical EPR Oximetry for Enhancing Cancer Therapy, Primary Investigator Instrumental Core.

Biological Advanced Research and Development Authority (BARDA) HHSO100201100024C. Aug 2011 – Aug 2015. In Vivo Electron Paramagnetic Resonance (EPR) Tooth Dosimetry for Rapid Point-of-Care Diagnostic Assessment of Absorbed Doses of Ionizing Radiation. Associate Director (Director: Harold Swartz).

NIH National Institute of Allergy and Infectious Disease (NIAID) Centers for Medical Countermeasures Against Radiation (CMCR) U19 AI091173. June 2010 - June 2015. Physically-Based Biodosimetry for Triage After a Large Radiation Incident. Associate Director (Director: Harold Swartz), Primary Investigator Project 1.

Courses Taught

Thayer School of Engineering, Dartmouth College. Engineering Sciences 167: Medical Imaging. (Guest Lecturer)

Thayer School of Engineering, Dartmouth College, Engineering Sciences 56: Introduction to Biomedical Engineering. (Guest Lecturer)

Thayer School of Engineering, Dartmouth College, Engineering Sciences 6: Technology & Biosecurity. (Guest Lecturer)

Thayer School of Engineering, Dartmouth College. Engineering Sciences 168: Biomedical Radiation Transport. (Guest Lecturer)

Selected Publications
 

  • Swartz HM, Flood AB, Gougelet RM, Nicolalde RJ, Rea ME, Williams BB A critical assessment of biodosimetry methods for large-scale incidents. Health Phys. Feb;98(2):95-108. (2010).

  • Khan N, Williams BB, Hou H, Li H, Swartz HM. Repetitive tissue pO2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies. Antioxid Redox Signal. 2007 Aug;9(8):1169-82. Review. (view details in PubMed)

  • Swartz HM, Williams BB, Nicolalde RJ, Demidenko E, Flood AB Overview of Biodosimetry for Management of Unplanned Exposures to Ionizing Radiation. Radiation Measurements 46:742-748. (2011)

  • Swartz HM, Burke G, Coey M, Demidenko E, Dong R, Grinberg O, Hilton J, Iwasaki A, Lesniewski P, Kmiec M, Lo K-M, Nicolalde RJ, Ruuge A, Salata Y, Sucheta A, Walczak T, Williams BB, Mitchell CA, Romanyukha A, Schauer DA. In vivo EPR for dosimetry. Radiation Measurements. 2007; 42:1075-1084.

  • Elas M, Williams BB, Parasca A, Mailer C, Pelizzari CA, Lewis MA, River JN, Karczmar GS, Barth ED, Halpern HJ. Quantitative tumor oxymetric images from 4D electron paramagnetic resonance imaging (EPRI): methodology and comparison with blood oxygen level-dependent (BOLD) MRI. Magn Reson Med. 2003 Apr;49(4):682-91. (view details in PubMed)

  • Demidenko E, Williams BB, Flood AB, Swartz HM Standard Error of Inverse Prediction for Dose-Response Relationship: Approximate and Exact Statistical Inference. Statistics in Medicine. 32(12): 2048–2061. (2013)

  • Williams BB, Dong R, Nicolalde RJ, Matthews TP, Gladstone DJ, Demidenko E, Zaki BI, Salikhov IK, Lesniewski PN, Swartz HM Physically-based Biodosimetry using In Vivo EPR of Teeth in Patients Undergoing Total Body Irradiation. International Journal of Radiation Biology. Aug;87(8):766-75. (2011)

  • Swartz HM, Williams BB, Zaki BI, Hartford AC, Jarvis LA, Chen EY, Comi RJ, Ernstoff MS, Hou H, Khan N, Swarts SG, Flood AB, Kuppusamy P Clinical EPR: Unique Opportunities and Some Challenges. Academic Radiology. 21:197-206. (2014)

  • Williams BB, Flood AB, Swartz HM In vivo EPR tooth dosimetry for triage after a radiation event involving large populations. Radiation and Environmental Biophysics. 53:335–346. (2014)

  • Swartz HM, Williams BB, Flood AB Overview of the principles and practice of biodosimetry. Radiation and Environmental Biophysics. 53:221–232. (2014)

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