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Richard J. Barth Jr, MD

Professor of Surgery


A.B. - Biochemical Sciences, Princeton, 1981.
M.D. - Harvard, 1985

Norris Cotton Cancer Center

Curriculum Vitae:

NIH Biosketch:


Contact Information:

1 Medical Center Drive
Lebanon NH 03756

Email: Richard.J.Barth.Jr@Hitchcock.ORG

Professional Interests:

This lab has been interested in understanding the immune response to tumors in vivo by characterizing the cytokines expressed by lymphocytes infiltrating tumors and the tumors themselves. We have recently demonstrated that CD40/CD154 interactions are crucial in the generation of anti-tumor immunity by tumor vaccines in mice. We are now actively investigating the mechanisms underlying this phenomenon, and are trying to exploit this in the generation of more effective vaccines.

Selected Publications:


Profiles of Surgical Entrepreneurs.
Barth RJ Jr
J Am Coll Surg. 2020 Mar 5; pii: S1072-7515(20)30221-0. doi: 10.1016/j.jamcollsurg.2019.12.046. Epub 2020 Mar 5.
PMID: 32147486

Association of Decreased Postsurgical Opioid Prescribing With Patients' Satisfaction With Surgeons.
Louie CE, Kelly JL, Barth RJ Jr
JAMA Surg. 2019 Oct 16; doi: 10.1001/jamasurg.2019.2875. Epub 2019 Oct 16.
PMID: 31617880

A Randomized Prospective Trial of Supine MRI-Guided Versus Wire-Localized Lumpectomy for Breast Cancer.
Barth RJ Jr, Krishnaswamy V, Paulsen KD, Rooney TB, Wells WA, Angeles CV, Zuurbier RA, Rosenkranz K, Poplack S, Tosteson TD
Ann Surg Oncol. 2019 Oct;26(10):3099-3108. doi: 10.1245/s10434-019-07531-4. Epub 2019 Jul 29.
PMID: 31359283

Small and Isolated Immunohistochemistry-positive Cells in Melanoma Sentinel Lymph Nodes Are Associated With Disease-specific and Recurrence-free Survival Comparable to that of Sentinel Lymph Nodes Negative for Melanoma.
LeBlanc RE, Barton DT, Li Z, Angeles CV, Ernstoff MS, Bagley E, Wimmer D, Wong SL, Barth RJ Jr, Shirai K, Yan S
Am J Surg Pathol. 2019 Jun;43(6):755-765. doi: 10.1097/PAS.0000000000001229.
PMID: 31091203

Borderline and Malignant Phyllodes Tumors: How Often do They Locally Recur and is There Anything we can do About it?
Barth RJ Jr
Ann Surg Oncol. 2019 Jul;26(7):1973-1975. doi: 10.1245/s10434-019-07278-y. Epub 2019 Mar 12.
PMID: 30863938

Impact of Autologous Blood Transfusion on Survival and Recurrence among Patients Undergoing Partial Hepatectomy for Colorectal Cancer Liver Metastases.
Kang R, Seath BE, Huang V, Barth RJ Jr
J Am Coll Surg. 2019 Jun;228(6):902-908. doi: 10.1016/j.jamcollsurg.2018.10.020. Epub 2018 Nov 16.
PMID: 30448300

Review of methods for intraoperative margin detection for breast conserving surgery.
Maloney BW, McClatchy DM, Pogue BW, Paulsen KD, Wells WA, Barth RJ
J Biomed Opt. 2018 Oct;23(10):1-19. doi: 10.1117/1.JBO.23.10.100901.
PMID: 30369108

Association of the Use of a Mandatory Prescription Drug Monitoring Program With Prescribing Practices for Patients Undergoing Elective Surgery.
Stucke RS, Kelly JL, Mathis KA, Hill MV, Barth RJ Jr
JAMA Surg. 2018 Dec 1;153(12):1105-1110. doi: 10.1001/jamasurg.2018.2666.
PMID: 30140927

Short-term Preoperative Diet Decreases Bleeding After Partial Hepatectomy: Results From a Multi-institutional Randomized Controlled Trial.
Barth RJ Jr, Mills JB, Suriawinata AA, Putra J, Tosteson TD, Axelrod D, Freeman R, Whalen GF, LaFemina J, Tarczewski SM, Kinlaw WB
Ann Surg. 2019 Jan;269(1):48-52. doi: 10.1097/SLA.0000000000002709.
PMID: 29489484

Personal history of proliferative breast disease with atypia and risk of multifocal breast cancer.
Nutter EL, Weiss JE, Marotti JD, Barth RJ Jr, Eliassen MS, Goodrich ME, Petersen CL, Onega T
Cancer. 2018 Apr 1;124(7):1350-1357. doi: 10.1002/cncr.31202. Epub 2017 Dec 20.
PMID: 29266172

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