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Tor D Tosteson, ScD

Title(s)
Professor of Biomedical Data Science
Professor of The Dartmouth Institute
Professor of Community and Family Medicine

Additional Titles/Positions/Affiliations
Director, Division of Biostatistics, Department of Biomedical Data Science

Department(s)
Biomedical Data Science
The Dartmouth Institute
Community and Family Medicine

Education
Biostatistics, Harvard University, SCD
Biostatistics, Harvard University, MS
Economics, University of North Carolina - Chapel Hill, BA

Programs
Norris Cotton Cancer Center
SYNERGY
The Dartmouth Institute for Health Policy and Clinical Practice

Websites
https://cancer.dartmouth.edu/about/cancer-center-leadership
https://bmds.dartmouth.edu/biostatistics

Contact Information

Geisel School of Medicine at Dartmouth
One Medical Center Drive
HB7927
Lebanon NH 03756

Office: Rubin 875
Phone: 603-653-3677
Email: tor.tosteson@dartmouth.edu

Assistant: Lamar Moss
Asst. Phone: (603) 650-1763
Asst. Email: lamar.d.moss@dartmouth.edu


Professional Interests

My current research interests revolve around challenging methodological and statistical problems in biomedical data science. I collaborate extensively in the areas of cancer and musculoskeletal disease involving clinical, translational and outcomes research. I develop related statistical methodology in the areas of covariate measurement error for nonlinear regression models, clinical trials, instrumental variables,joint modeling of survival and longitudinal patient outcomes, and randomization in learning health systems.

Grant Information


T32 CA134286-11 Training Program for Quantitative Population Sciences in Cancer (MPI)
NCI P30 CA023108-41 Biostatistics and Bioinformatics (BBSR) (Subaward PI)
T32 LM012204-05 Predoctoral Training in Quantitative Biomedical Sciences at Dartmouth (PI)



Courses Taught

QBS Fundamentals of Biostatistics I & II; QBS Statistical Consulting

Biography

Prior to coming to Dartmouth, I spent 5 years on the faculties of Harvard Medical School at the Channing Laboratory, and Harvard School of Public Health in the Department of Biostatistics. I was elected as a Fellow of the American Statistical Association in 2014.

Mentoring Information

I am an active mentor for pre and post docs and junior faculty and lead 2 NIH training grants.


Selected Publications

 

Preventing metastatic recurrence in low-risk ER/PR + breast cancer patients-a retrospective clinical study exploring the evolving challenge of persistence with adjuvant endocrine therapy.
Kuhn EP, Pirruccello J, Boothe JT, Li Z, Tosteson TD, Stahl JE, Schwartz GN, Chamberlin MD
Breast Cancer Res Treat. 2023 Feb;198(1):31-41. doi: 10.1007/s10549-022-06849-0. Epub 2023 Jan 2.
PMID: 36592233

A phase I trial of BNC105P and ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia.
Pooler DB, Ness DB, Danilov AV, Labrie BM, Tosteson TD, Eastman A, Lewis LD, Lansigan F
EJHaem. 2022 Nov;3(4):1445-1448. doi: 10.1002/jha2.543. Epub 2022 Aug 11.
PMID: 36467840

Sensitizing brain metastases to stereotactic radiosurgery using hyperbaric oxygen: A proof-of-principle study.
Hartford AC, Gill GS, Ravi D, Tosteson TD, Li Z, Russo G, Eskey CJ, Jarvis LA, Simmons NE, Evans LT, Williams BB, Gladstone DJ, Roberts DW, Buckey JC Jr
Radiother Oncol. 2022 Dec;177:179-184. doi: 10.1016/j.radonc.2022.10.024. Epub 2022 Oct 28.
PMID: 36404528

Adoption of Telemedicine in a Rural US Cancer Center Amid the COVID-19 Pandemic: Qualitative Study.
Mackwood M, Butcher R, Vaclavik D, Alford-Teaster JA, Curtis KM, Lowry M, Tosteson TD, Zhao W, Tosteson ANA
JMIR Cancer. 2022 Aug 16;8(3):e33768. doi: 10.2196/33768. Epub 2022 Aug 16.
PMID: 35895904

Factors Influencing Telemedicine Use at a Northern New England Cancer Center During the COVID-19 Pandemic.
Mackwood MB, Tosteson TD, Alford-Teaster JA, Curtis KM, Lowry ML, Snide JA, Zhao W, Tosteson ANA
JCO Oncol Pract. 2022 Jul;18(7):e1141-e1153. doi: 10.1200/OP.21.00750. Epub 2022 Apr 21.
PMID: 35446680

Effectiveness of a Self-Management Program to Improve Cognition and Quality of Life in Epilepsy: A Pragmatic, Randomized, Multicenter Trial.
Streltzov NA, Schmidt SS, Schommer LM, Zhao W, Tosteson TD, Mazanec MT, Kiriakopoulos ET, Chu F, Henninger HL, Nagle K, Roth RM, Jobst B
Neurology. 2022 May 24;98(21):e2174-e2184. doi: 10.1212/WNL.0000000000200346. Epub 2022 Apr 6.
PMID: 35387855

Colonoscopy utilization and outcomes in older adults: Data from the New Hampshire Colonoscopy Registry.
Calderwood AH, Tosteson TD, Walter LC, Hua P, Onega T
J Am Geriatr Soc. 2022 Mar;70(3):801-811. doi: 10.1111/jgs.17560. Epub 2021 Dec 3.
PMID: 34859887

Guidance for biostatisticians on their essential contributions to clinical and translational research protocol review.
Ciolino JD, Spino C, Ambrosius WT, Khalatbari S, Cayetano SM, Lapidus JA, Nietert PJ, Oster RA, Perkins SM, Pollock BH, Pomann GM, Price LL, Rice TW, Tosteson TD, Lindsell CJ, Spratt H
J Clin Transl Sci. 2021;5(1):e161. doi: 10.1017/cts.2021.814. Epub 2021 Jul 12.
PMID: 34527300

Pathogenic DPYD Variants and Treatment-Related Mortality in Patients Receiving Fluoropyrimidine Chemotherapy: A Systematic Review and Meta-Analysis.
Sharma BB, Rai K, Blunt H, Zhao W, Tosteson TD, Brooks GA
Oncologist. 2021 Dec;26(12):1008-1016. doi: 10.1002/onco.13967. Epub 2021 Sep 29.
PMID: 34506675

Pandemic Use of Telehealth by Oncology at a Rural Academic Medical Center.
Curtis K, Alford-Teaster J, Lowry M, Mackwood M, Snide J, Tosteson T, Tosteson A
Telemed J E Health. 2022 Apr;28(4):501-508. doi: 10.1089/tmj.2020.0556. Epub 2021 Jul 20.
PMID: 34287089

View more publications on PubMed