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Tor D Tosteson, ScD

Professor of Biomedical Data Science
Professor of The Dartmouth Institute
Professor of Community and Family Medicine

Additional Titles/Positions/Affiliations:
Director, Division of Biostatistics, Department of Biomedical Data Science

Biomedical Data Science
The Dartmouth Institute
Community and Family Medicine

Biostatistics, Harvard University, SCD
Biostatistics, Harvard University, MS
Economics, University of North Carolina - Chapel Hill, BA

Norris Cotton Cancer Center
The Dartmouth Institute for Health Policy and Clinical Practice


Contact Information:

Geisel School of Medicine at Dartmouth
One Medical Center Drive
Lebanon NH 03756

Office: Rubin 875
Phone: 603-653-3677

Assistant: Lamar Moss
Asst. Phone: (603) 650-1763
Asst. Email:

Professional Interests:

My current research interests revolve around challenging methodological and statistical problems in biomedical data science. I collaborate extensively in the areas of cancer and musculoskeletal disease involving clinical, translational and outcomes research. I develop related statistical methodology in the areas of covariate measurement error for nonlinear regression models, clinical trials, instrumental variables,joint modeling of survival and longitudinal patient outcomes, and randomization in learning health systems.

Grant Information:

2R25CA134286 Training Program for Quantitative Population Sciences in Cancer (PI: T.Tosteson)
6P30CA23108-37 Sub Award 5354 NCCC Biostatistics Shared Resource (PI: T. Tosteson)
PCORI Contract ME-1609-36174 Tosteson, T (PI) 02/1/18 - 1/31/22
Title: "Randomize Everyone": Creating Valid Instrumental Variables for Learning Health Care Systems

Courses Taught:

QBS Fundamentals of Biostatistics I & II; QBS Statistical Consulting; SYNERGY Certificate Program.


Prior to coming to Dartmouth, I spent 5 years on the faculties of Harvard Medical School at the Channing Laboratory, and Harvard School of Public Health in the Department of Biostatistics. I was elected as a Fellow of the American Statistical Association in 2014.

Mentoring Information:

I am an active mentor for pre and post docs and junior faculty.

Selected Publications:


A Randomized Prospective Trial of Supine MRI-Guided Versus Wire-Localized Lumpectomy for Breast Cancer.
Barth RJ Jr, Krishnaswamy V, Paulsen KD, Rooney TB, Wells WA, Angeles CV, Zuurbier RA, Rosenkranz K, Poplack S, Tosteson TD
Ann Surg Oncol. 2019 Oct;26(10):3099-3108. doi: 10.1245/s10434-019-07531-4. Epub 2019 Jul 29.
PMID: 31359283

Multi-level Influences on Breast Cancer Screening in Primary Care.
Onega T, Tosteson TD, Weiss J, Haas JS, Goodrich M, DiFlorio R, Brackett C, Clark C, Harris K, Tosteson ANA
J Gen Intern Med. 2018 Oct;33(10):1729-1737. doi: 10.1007/s11606-018-4560-1. Epub 2018 Aug 3.
PMID: 30076569

Medical Care Costs Were Similar Across the Low-dose Computed Tomography and Chest X-Ray Arms of the National Lung Screening Trial Despite Different Rates of Significant Incidental Findings.
Gareen IF, Black WC, Tosteson TD, Wang Q, Sicks JD, Tosteson ANA
Med Care. 2018 May;56(5):403-409. doi: 10.1097/MLR.0000000000000900.
PMID: 29613874

A semiparametric joint model for terminal trend of quality of life and survival in palliative care research.
Li Z, Frost HR, Tosteson TD, Zhao L, Liu L, Lyons K, Chen H, Cole B, Currow D, Bakitas M
Stat Med. 2017 Dec 20;36(29):4692-4704. doi: 10.1002/sim.7445. Epub 2017 Aug 17.
PMID: 28833347

Diffusion of digital breast tomosynthesis among women in primary care: associations with insurance type.
Clark CR, Tosteson TD, Tosteson ANA, Onega T, Weiss JE, Harris KA, Haas JS
Cancer Med. 2017 May;6(5):1102-1107. doi: 10.1002/cam4.1036. Epub 2017 Apr 4.
PMID: 28378409

Medical home transformation and breast cancer screening.
Baughman AW, Brawarsky P, Onega T, Tosteson TD, Wang Q, Tosteson AN, Haas JS
Am J Manag Care. 2016 Nov 1;22(11):e382-e388. Epub 2016 Nov 1.
PMID: 27849352

Patterns of Prescription Drug Use Before and After Fragility Fracture.
Munson JC, Bynum JP, Bell JE, Cantu R, McDonough C, Wang Q, Tosteson TD, Tosteson AN
JAMA Intern Med. 2016 Oct 1;176(10):1531-1538. doi: 10.1001/jamainternmed.2016.4814.
PMID: 27548843

Risk Factors for Reoperation in Patients Treated Surgically for Intervertebral Disc Herniation: A Subanalysis of Eight-Year SPORT Data.
Leven D, Passias PG, Errico TJ, Lafage V, Bianco K, Lee A, Lurie JD, Tosteson TD, Zhao W, Spratt KF, Morgan TS, Gerling MC
J Bone Joint Surg Am. 2015 Aug 19;97(16):1316-25. doi: 10.2106/JBJS.N.01287.
PMID: 26290082

A Pilot Study of Ultrasound-Guided Cryoablation of Invasive Ductal Carcinomas up to 15 mm With MRI Follow-Up and Subsequent Surgical Resection.
Poplack SP, Levine GM, Henry L, Wells WA, Heinemann FS, Hanna CM, Deneen DR, Tosteson TD, Barth RJ Jr
AJR Am J Roentgenol. 2015 May;204(5):1100-8. doi: 10.2214/AJR.13.12325.
PMID: 25905948

Evaluation of an Automated Information Extraction Tool for Imaging Data Elements to Populate a Breast Cancer Screening Registry.
Lacson R, Harris K, Brawarsky P, Tosteson TD, Onega T, Tosteson AN, Kaye A, Gonzalez I, Birdwell R, Haas JS
J Digit Imaging. 2015 Oct;28(5):567-75. doi: 10.1007/s10278-014-9762-4.
PMID: 25561069

View more publications on PubMed