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Tor D Tosteson, ScD

Title(s)
Professor of Biomedical Data Science
Professor of The Dartmouth Institute
Professor of Community and Family Medicine

Additional Titles/Positions/Affiliations
Director, Division of Biostatistics, Department of Biomedical Data Science

Department(s)
Biomedical Data Science
The Dartmouth Institute
Community and Family Medicine

Education
Biostatistics, Harvard University, SCD
Biostatistics, Harvard University, MS
Economics, University of North Carolina - Chapel Hill, BA

Programs
Dartmouth Cancer Center
SYNERGY
The Dartmouth Institute for Health Policy and Clinical Practice

Websites
https://cancer.dartmouth.edu/about/cancer-center-leadership
https://bmds.dartmouth.edu/biostatistics

Contact Information

Geisel School of Medicine at Dartmouth
One Medical Center Drive
HB7927
Lebanon NH 03756

Office: Rubin 875
Phone: 603-653-3677
Email: tor.tosteson@dartmouth.edu

Assistant: Lamar Moss
Asst. Phone: (603) 650-1763
Asst. Email: lamar.d.moss@dartmouth.edu


Professional Interests

My current research interests revolve around challenging methodological and statistical problems in biomedical data science. I collaborate extensively in the areas of cancer and musculoskeletal disease involving clinical, translational and outcomes research. I develop related statistical methodology in the areas of covariate measurement error for nonlinear regression models, clinical trials, instrumental variables,joint modeling of survival and longitudinal patient outcomes, and randomization in learning health systems.

Grant Information


T32 CA134286-11 Training Program for Quantitative Population Sciences in Cancer (MPI)
NCI P30 CA023108-41 Biostatistics and Bioinformatics (BBSR) (Subaward PI)
T32 LM012204-05 Predoctoral Training in Quantitative Biomedical Sciences at Dartmouth (PI)



Courses Taught

QBS Fundamentals of Biostatistics I & II; QBS Statistical Consulting

Mentoring Information

I am an active mentor for pre and post docs and junior faculty and lead 2 NIH training grants.

Biography

Prior to coming to Dartmouth, I spent 5 years on the faculties of Harvard Medical School at the Channing Laboratory, and Harvard School of Public Health in the Department of Biostatistics. I was elected as a Fellow of the American Statistical Association in 2014.


Selected Publications

 

Association of DPYD rs4294451, plasma uracil concentration, and sex with 5-fluorouracil exposure in patients with gastrointestinal cancer.
Brooks GA, Ness DB, Hourdequin KC, Ripple GH, Amin M, Lord-Halvorson S, Khan WA, Deharvengt SJ, Busque V, Dragnev KH, Zhao W, Tosteson TD, Lewis LD
Cancer Chemother Pharmacol. 2025 Dec 4;95(1):120. doi: 10.1007/s00280-025-04851-z. Epub 2025 Dec 4.
PMID: 41339584

Comparing Trends in Telemedicine Use and Geographic Disparities in Utilization Among Patients With Cancer in the United States.
Mackwood M, Wang Q, Tosteson TD, Brooks G, Smith RE, Tosteson ANA
JCO Oncol Pract. 2025 Oct 9;:OP2400751. doi: 10.1200/OP-24-00751. Epub 2025 Oct 9.
PMID: 41066715

A pragmatic, single-arm clinical trial of a dose modification algorithm for preventing cytopenia-related delays during FOLFOX chemotherapy.
Wright HN, Tosteson TD, Hourdequin KC, Ripple GH, Fuld AD, Dragnev KH, Amin M, Muralikrishnan S, McGrath EB, Stannard MG, Schofield LL, Lord-Halvorson S, Tosteson ANA, Brooks GA
Support Care Cancer. 2025 Aug 8;33(9):769. doi: 10.1007/s00520-025-09784-0. Epub 2025 Aug 8.
PMID: 40779182

Peer review of clinical and translational research manuscripts: Perspectives from statistical collaborators.
Schulte PJ, Goldberg JD, Oster RA, Ambrosius WT, Bonner LB, Cabral H, Carter RE, Chen Y, Desai M, Li D, Lindsell CJ, Pomann GM, Slade E, Tosteson TD, Yu F, Spratt H
J Clin Transl Sci. 2024;8(1):e20. doi: 10.1017/cts.2023.707. Epub 2024 Jan 4.
PMID: 38384899

Evaluating Physician Emotion Regulation in Serious Illness Conversations Using Multimodal Assessment.
Wasp GT, Kaur-Gill S, Anderson EC, Vergo MT, Chelen J, Tosteson T, Barr PJ, Barnato AE
J Pain Symptom Manage. 2023 Oct;66(4):351-360.e1. doi: 10.1016/j.jpainsymman.2023.07.001. Epub 2023 Jul 9.
PMID: 37433418

Association of Life Expectancy With Surveillance Colonoscopy Findings and Follow-up Recommendations in Older Adults.
Calderwood AH, Tosteson TD, Wang Q, Onega T, Walter LC
JAMA Intern Med. 2023 May 1;183(5):426-434. doi: 10.1001/jamainternmed.2023.0078.
PMID: 36912828

Preventing metastatic recurrence in low-risk ER/PR + breast cancer patients-a retrospective clinical study exploring the evolving challenge of persistence with adjuvant endocrine therapy.
Kuhn EP, Pirruccello J, Boothe JT, Li Z, Tosteson TD, Stahl JE, Schwartz GN, Chamberlin MD
Breast Cancer Res Treat. 2023 Feb;198(1):31-41. doi: 10.1007/s10549-022-06849-0. Epub 2023 Jan 2.
PMID: 36592233

A phase I trial of BNC105P and ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia.
Pooler DB, Ness DB, Danilov AV, Labrie BM, Tosteson TD, Eastman A, Lewis LD, Lansigan F
EJHaem. 2022 Nov;3(4):1445-1448. doi: 10.1002/jha2.543. Epub 2022 Aug 11.
PMID: 36467840

Sensitizing brain metastases to stereotactic radiosurgery using hyperbaric oxygen: A proof-of-principle study.
Hartford AC, Gill GS, Ravi D, Tosteson TD, Li Z, Russo G, Eskey CJ, Jarvis LA, Simmons NE, Evans LT, Williams BB, Gladstone DJ, Roberts DW, Buckey JC Jr
Radiother Oncol. 2022 Dec;177:179-184. doi: 10.1016/j.radonc.2022.10.024. Epub 2022 Oct 28.
PMID: 36404528

Adoption of Telemedicine in a Rural US Cancer Center Amid the COVID-19 Pandemic: Qualitative Study.
Mackwood M, Butcher R, Vaclavik D, Alford-Teaster JA, Curtis KM, Lowry M, Tosteson TD, Zhao W, Tosteson ANA
JMIR Cancer. 2022 Aug 16;8(3):e33768. doi: 10.2196/33768. Epub 2022 Aug 16.
PMID: 35895904

View more publications on PubMed