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Tor D Tosteson, ScD

Professor of Biomedical Data Science
Professor of The Dartmouth Institute
Professor of Community and Family Medicine

Additional Titles/Positions/Affiliations:
Director, Division of Biostatistics, Department of Biomedical Data Science

Biomedical Data Science
The Dartmouth Institute
Community and Family Medicine

Biostatistics, Harvard University, SCD
Biostatistics, Harvard University, MS
Economics, University of North Carolina - Chapel Hill, BA

Norris Cotton Cancer Center
The Dartmouth Institute for Health Policy and Clinical Practice


Contact Information:

Geisel School of Medicine at Dartmouth
One Medical Center Drive
Lebanon NH 03756

Office: Rubin 875
Phone: 603-653-3677

Assistant: Lamar Moss
Asst. Phone: (603) 650-1763
Asst. Email:

Professional Interests:

My current research interests revolve around challenging methodological and statistical problems in biomedical data science. I collaborate extensively in the areas of cancer and musculoskeletal disease involving clinical, translational and outcomes research. I develop related statistical methodology in the areas of covariate measurement error for nonlinear regression models, clinical trials, instrumental variables,joint modeling of survival and longitudinal patient outcomes, and randomization in learning health systems.

Grant Information:

T32 CA134286-11 Training Program for Quantitative Population Sciences in Cancer (MPI)
NCI P30 CA023108-41 Biostatistics and Bioinformatics (BBSR) (Subaward PI)
T32 LM012204-05 Predoctoral Training in Quantitative Biomedical Sciences at Dartmouth (PI)

Courses Taught:

QBS Fundamentals of Biostatistics I & II; QBS Statistical Consulting


Prior to coming to Dartmouth, I spent 5 years on the faculties of Harvard Medical School at the Channing Laboratory, and Harvard School of Public Health in the Department of Biostatistics. I was elected as a Fellow of the American Statistical Association in 2014.

Mentoring Information:

I am an active mentor for pre and post docs and junior faculty and lead 2 NIH training grants.

Selected Publications:


Guidance for biostatisticians on their essential contributions to clinical and translational research protocol review.
Ciolino JD, Spino C, Ambrosius WT, Khalatbari S, Cayetano SM, Lapidus JA, Nietert PJ, Oster RA, Perkins SM, Pollock BH, Pomann GM, Price LL, Rice TW, Tosteson TD, Lindsell CJ, Spratt H
J Clin Transl Sci. 2021;5(1):e161. doi: 10.1017/cts.2021.814. Epub 2021 Jul 12.
PMID: 34527300

Pathogenic DPYD Variants and Treatment-Related Mortality in Patients Receiving Fluoropyrimidine Chemotherapy: A Systematic Review and Meta-Analysis.
Sharma BB, Rai K, Blunt H, Zhao W, Tosteson TD, Brooks GA
Oncologist. 2021 Sep 10; doi: 10.1002/onco.13967. Epub 2021 Sep 10.
PMID: 34506675

Pandemic Use of Telehealth by Oncology at a Rural Academic Medical Center.
Curtis K, Alford-Teaster J, Lowry M, Mackwood M, Snide J, Tosteson T, Tosteson A
Telemed J E Health. 2021 Jul 20; doi: 10.1089/tmj.2020.0556. Epub 2021 Jul 20.
PMID: 34287089

Journey across epidemiology's third variables: an anesthesiologist's guide for successfully navigating confounding, mediation, and effect modification.
Levy J, Lebeaux R, Christensen B, Tosteson T, Bryan Y
Reg Anesth Pain Med. 2021 Nov;46(11):936-940. doi: 10.1136/rapm-2020-101984. Epub 2021 May 21.
PMID: 34021076

Geriatric Snowmobile Trauma: Longer Courses After Similar Injuries.
Goldwag JL, Porter ED, Wilcox AR, Li Z, Tosteson TD, Crockett AO, Wolffing AB, Mancini DJ, Martin ED, Scott JW, Briggs A
J Surg Res. 2021 Jun;262:85-92. doi: 10.1016/j.jss.2020.12.060. Epub 2021 Feb 4.
PMID: 33549849

Kynurenine-Induced Aryl Hydrocarbon Receptor Signaling in Mice Causes Body Mass Gain, Liver Steatosis, and Hyperglycemia.
Rojas IY, Moyer BJ, Ringelberg CS, Wilkins OM, Pooler DB, Ness DB, Coker S, Tosteson TD, Lewis LD, Chamberlin MD, Tomlinson CR
Obesity (Silver Spring). 2021 Feb;29(2):337-349. doi: 10.1002/oby.23065.
PMID: 33491319

Geriatric Skiers: Active But Still at Risk, a National Trauma Data Bank Study.
Porter ED, Goldwag JL, Wilcox AR, Li Z, Tosteson TD, Mancini DJ, Wolffing AB, Martin E, Crockett AO, Scott JW, Briggs A
J Surg Res. 2021 Mar;259:121-129. doi: 10.1016/j.jss.2020.11.013. Epub 2020 Dec 3.
PMID: 33279837

Integration of Registries with EHRs to Accelerate Generation of Real-World Evidence for Clinical Practice and Learning Health Systems Research: Recommendations from a Workshop on Registry Best Practices.
Franklin PD, Lurie J, Tosteson TD, Tosteson ANA, Task Force on Musculoskeletal Registries.
J Bone Joint Surg Am. 2020 Oct 7;102(19):e110. doi: 10.2106/JBJS.19.01464.
PMID: 33027129

Zheng Y, Corley DA, Doubeni C, Halm E, Shortreed SM, Barlow WE, Zauber A, Tosteson TD, Chubak J
Ann Appl Stat. 2020 Jun;14(2):1030-1044. doi: 10.1214/20-aoas1342. Epub 2020 Jun 29.
PMID: 34531936

A Randomized Prospective Trial of Supine MRI-Guided Versus Wire-Localized Lumpectomy for Breast Cancer.
Barth RJ Jr, Krishnaswamy V, Paulsen KD, Rooney TB, Wells WA, Angeles CV, Zuurbier RA, Rosenkranz K, Poplack S, Tosteson TD
Ann Surg Oncol. 2019 Oct;26(10):3099-3108. doi: 10.1245/s10434-019-07531-4. Epub 2019 Jul 29.
PMID: 31359283

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