Edit Entry | Edit CV

Michael W. Fanger, PhD

Emeritus Professor of Microbiology and Immunology

Microbiology and Immunology

Yale University, Ph.D., 1967

Wabash College, B.A., 1962

Professor Fanger received the B.A. degree from Wabash College in 1962 and the Ph.D. in Biochemistry from Yale University in 1967. After postdoctoral training at the National Institute for Medical Research in London, England and the University of Illinois Medical School in Chicago, he was appointed to the faculty of the Microbiology Department at Case Western Reserve University in Cleveland in 1970. In 1981, Professor Fanger moved to the Dartmouth Medical School. He served as Chair of the Department of Microbiology and Immunology from 1992 to 2002, and is currently Professor of Microbiology and Immunology, and Professor of Medicine.

Immunology Program


Academic Analytics
View Profile

Contact Information

Dartmouth Medical School
Borwell Research Building-HB 7556
1 Medical Center Drive
Lebanon NH 03756

Office: Borwell 600W
Phone: 603-650-7505
Fax: 603-650-6223
Email: Michael.W.Fanger@Dartmouth.EDU

Professional Interests

Research in Dr. Fanger's laboratory has focused on studies of the role that innate immunity plays in inducing adaptive immunity in the human female reproductive tract and on the mechanisms by which antigen presentation is mediated by human Dendritic Cells (DCs). As DCs play a major role in the initiation of immunity through processing and presentation of antigen, fusion proteins that target antigens to molecules expressed primarily on antigen presenting cells are being investigated as vaccines for immunotherapy of cancer.

Courses Taught

Biology 42

Selected Publications


Manufacturing development and clinical production of NKG2D chimeric antigen receptor-expressing T cells for autologous adoptive cell therapy.
Murad JM, Baumeister SH, Werner L, Daley H, Trebeden-Negre H, Reder J, Sentman CL, Gilham D, Lehmann F, Snykers S, Sentman ML, Wade T, Schmucker A, Fanger MW, Dranoff G, Ritz J, Nikiforow S
Cytotherapy. 2018 Jul;20(7):952-963. doi: 10.1016/j.jcyt.2018.05.001. Epub 2018 Jun 29.
PMID: 30180944

Mechanisms of Acute Toxicity in NKG2D Chimeric Antigen Receptor T Cell-Treated Mice.
Sentman ML, Murad JM, Cook WJ, Wu MR, Reder J, Baumeister SH, Dranoff G, Fanger MW, Sentman CL
J Immunol. 2016 Dec 15;197(12):4674-4685. Epub 2016 Nov 14.
PMID: 27849169

Effects of menstrual cycle status and gender on human neutrophil phenotype.
Smith JM, Shen Z, Wira CR, Fanger MW, Shen L
Am J Reprod Immunol. 2007 Aug;58(2):111-9.
PMID: 17631004

Human fallopian tube neutrophils--a distinct phenotype from blood neutrophils.
Smith JM, Wira CR, Fanger MW, Shen L
Am J Reprod Immunol. 2006 Oct;56(4):218-29.
PMID: 16938110

Differential regulation of neutrophil chemotaxis to IL-8 and fMLP by GM-CSF: lack of direct effect of oestradiol.
Shen L, Smith JM, Shen Z, Hussey SB, Wira CR, Fanger MW
Immunology. 2006 Feb;117(2):205-12.
PMID: 16423056

Chemokine receptor expression in the human ectocervix: implications for infection by the human immunodeficiency virus-type I.
Yeaman GR, Asin S, Weldon S, Demian DJ, Collins JE, Gonzalez JL, Wira CR, Fanger MW, Howell AL
Immunology. 2004 Dec;113(4):524-33.
PMID: 15554931

Synergy between IL-8 and GM-CSF in reproductive tract epithelial cell secretions promotes enhanced neutrophil chemotaxis.
Shen L, Fahey JV, Hussey SB, Asin SN, Wira CR, Fanger MW
Cell Immunol. 2004 Jul;230(1):23-32.
PMID: 15541716

Transmission of HIV-1 by primary human uterine epithelial cells and stromal fibroblasts.
Asin SN, Fanger MW, Wildt-Perinic D, Ware PL, Wira CR, Howell AL
J Infect Dis. 2004 Jul 15;190(2):236-45. Epub 2004 Jun 11.
PMID: 15216456

Inhibition of human polymorphonuclear cell oxidative burst by 17-beta-estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Abrahams VM, Collins JE, Wira CR, Fanger MW, Yeaman GR
Am J Reprod Immunol. 2003 Dec;50(6):463-72.
PMID: 14750553

Human immunodeficiency virus type 1 infection of human uterine epithelial cells: viral shedding and cell contact-mediated infectivity.
Asin SN, Wildt-Perinic D, Mason SI, Howell AL, Wira CR, Fanger MW
J Infect Dis. 2003 May 15;187(10):1522-33. Epub 2003 Apr 23.
PMID: 12721932

View more publications on PubMed