Jay C. Dunlap, PhD
Title(s)
Professor of Molecular and Systems Biology
Professor of Biochemistry and Cell Biology
Nathan Smith Professor
Department(s)
Molecular and Systems Biology
Biochemistry and Cell Biology
Education
Harvard University, Ph.D. 1979
Programs
Molecular and Cellular Biology Graduate Programs
Contact Information
Dartmouth Medical School
HB 7400
Hanover NH 03755
Office: 603-650-1907
Phone: 603-650-1108
Fax: 603-650-1233
Email: jay.dunlap@Dartmouth.edu
Assistant: Cheryl Bush
Asst. Phone: 603-650-1907
Asst. Email: genetics@dartmouth.edu
Professional Interests
Dr. Dunlap's laboratory is interested in understanding the mechanism by which eukaryotic organisms, including humans, keep time on a daily basis, and how this capacity to keep time is used to regulate metabolism and development. They have cloned "clock genes" as a first step towards identifying gears in the circadian oscillator , have isolated genes whose activities are controlled on a daily basis by the clock, and are studying the means by which the clock controls gene expression.
Grant Information
Dr. Dunlap is supported by an R35 MIRA grant from NIGMS and a U01 consortium grant from NIBIB.
Trends in circadian rhythms research in fungi since the millenium. Roles for Phosphatase PP4 in Rhythmicity and Compensation in the Neurospora Circadian System. A Screen To Identify Protein Phosphatases with Roles in Circadian Period, Temperature Compensation and Output in the Neurospora Circadian Clock. Core clock protein subcellular dynamics coordinate local and global circadian control in syncytia. The Case for Kinases: A Phosphorylation Driven Model for Circadian Temperature Compensation. Rhythmic nuclear import mediated by importins regulates the Neurospora circadian clock. Cell-Autonomous and Systemic Circadian Regulation of Gene Expression in Adipocytes. A daily cycle of White Collar Complex dephosphorylation sustains circadian rhythmicity in Neurospora. Rhythmic Nuclear Import Mediated by Importins Regulates the Neurospora Circadian Clock. Core Clock Protein Subcellular Dynamics Coordinate Local and Global Circadian Control in Syncytia. |
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