{"id":19,"date":"2013-05-19T23:47:56","date_gmt":"2013-05-19T23:47:56","guid":{"rendered":"http:\/\/dartmouse01.wordpress.com\/?page_id=6"},"modified":"2018-12-10T16:53:49","modified_gmt":"2018-12-10T16:53:49","slug":"services-and-pricing","status":"publish","type":"page","link":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/services-and-pricing\/","title":{"rendered":"Services"},"content":{"rendered":"<p><b>DartMouse\u2122<\/b><b>\u00a0<\/b>offers clients a\u00a0marker-assisted congenic breeding strategy<i>\u00a0<\/i>to produce congenic mice with &gt;99% recipient strain genetic purity in\u00a0half the time (5 generations; 1.25-1.5 years) instead of the more practiced 10-20 generations, which can take greater than 5 years.<b> <\/b><\/p>\n<ul>\n<li>DartMouse uses the Illumina Infinium Genotyping Assay to examine SNPs (single nucleotide polymorphisms) throughout the mouse genome \u2013 with analysis of the data we can help you select the \u201cbest\u201d (most-like your genetic background of interest) mouse to backcross for the next generation.\u00a0\u00a0Using this speed congenic approach saves valuable time and money.<\/li>\n<\/ul>\n<ul>\n<li>Each experimental sample is interrogated for over 5300 SNPs spaced throughout the mouse genome with an average density of 0.5 Mbp providing very detailed interval mapping.<\/li>\n<\/ul>\n<p><strong>Instrumentation<\/strong><br \/>\nThe workhorse of our analysis is the Illumina iScan SNP-Chip Reader.\u00a0This piece of equipment is serviced yearly by the manufacturer to ensure that the lasers and cameras are optimally calibrated.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DartMouse\u2122\u00a0offers clients a\u00a0marker-assisted congenic breeding strategy\u00a0to produce congenic mice with &gt;99% recipient strain genetic purity in\u00a0half the time (5 generations; 1.25-1.5 years) instead of the more practiced 10-20 generations, which can take greater than 5 years. DartMouse uses the Illumina Infinium Genotyping Assay to examine SNPs (single nucleotide polymorphisms) throughout [\u2026] <\/p>\n<div class=\"clear\"><\/div>\n<p><a class=\"more_link clearfix\" href=\"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/services-and-pricing\/\" rel=\"nofollow\">Read More<\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-19","page","type-page","status-publish","hentry","author-9"],"_links":{"self":[{"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/pages\/19","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/comments?post=19"}],"version-history":[{"count":2,"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/pages\/19\/revisions"}],"predecessor-version":[{"id":232,"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/pages\/19\/revisions\/232"}],"wp:attachment":[{"href":"https:\/\/geiselmed.dartmouth.edu\/dartmouse\/wp-json\/wp\/v2\/media?parent=19"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}