DartLab

We Aspire To

‘…… the right answer, the first time, with the least variability’

We provide a wide variety of human and mouse immunology services.  These include up to 20-color cell subset phenotyping and intracellular staining, lymphoproliferation assays, ELISPOTs, and multiplexed cytokine determination.

We also provide operator-assisted cell sorting (FACS) and round-the-clock access to a variety of flow cytometers.

Quality control is a priority of our Shared Resource as is proficiency testing of our Technologists. We  conduct proficiency testing on an annual basis where possible and participate in multiple proficiency testing programs.

DartLab staff are available for consultation and assistance with planning, execution, analysis and interpretation of immunological assays and multi-color flow cytometry.

We encourage users to become self-sufficient and have an active teaching and training program, including a 5-lecture flow cytometry course taught by DartLab staff.

In addition, our services are available to Pharma for clinical trial end-point assays on a fee-for-service basis.  End-point assays aid in the monitoring of the trial’s efficacy for treatments and prophylaxis/prevention.  We consult on, and develop, customized end-point immunoassays.

About Us

The Flow Cytometry Laboratory was established as a service core in Dartmouth Medical School in 1981 and became a Norris Cotton Cancer Center (NCCC) core in 1998. The Immune Monitoring Laboratory was established by Dr Channon Smith in 2002 with funds obtained by Drs Lloyd Kasper and Randy Noelle, together with COBRE and Cancer Center funds, specifically to carry out correlative immunological endpoint assays for clinical trials, in addition to basic immunology research at Dartmouth Hitchcock Medical Center (DHMC).

In 2010 the two laboratories were combined under the direction of Dr Channon Smith. The consolidated Shared Resource moves beyond the simple provisioning of technical services to making complex experiments possible by providing scientific and technological support for implementing advanced, high-complexity assays in a cost-effective way, and by providing a mechanism for the acquisition of new methodologies. This Shared Resource is unique, not only at Dartmouth, but also regionally.

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Contact Us

Director
Jacqueline Channon Smith
(603) 653-9916
722 Rubin

Assistant Director
Dan Mielcarz
(603) 653-9925
720 Rubin

Flow Cytometry Lab Manager
Gary Ward
(603) 650-7907
336W Borwell

Immune Monitoring Lab Manager
Alan Bergeron
(603) 653-9914
710 Rubin

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