Dartmouth researchers have identified nine traits that are not dependent on P values to predict single nucleotide polymorphisms (SNP) reproducibility in genome-wide association studies (GWAS) and reduce false positives
Post Tagged with: "genetics"
Geisel Researcher Receives Data-Driven Discovery Grant from Gordon and Betty Moore Foundation
Casey Greene, PhD, an assistant professor of genetics at Dartmouth’s Geisel School of Medicine, has been selected for a highly competitive award from the Gordon and Betty Moore Foundation to support his work to bring the power of big data into the biology lab.
Assortativity Signatures of Transcription Factor Networks (TFNs)Contribute to Robustness
Dartmouth researchers explored the type and number of connections in transcription factor networks (TFNs) to evaluate the role assortativity plays on robustness in a study published in PLOS Computational Biology in August. The study found that the assortativity signature contributes to a network’s resilience against mutations.
Mutation to BRCA2 Gene Can Double the Risk of Lung Cancer in Smokers
New research by an international group of scientists confirms a vulnerability to lung cancer can be inherited and implicates the BRCA2 gene as harboring one of the involved genetic mutations.
Dartmouth Scientists Identify Genetic Blueprint for Cancers of the Appendix
Using next generation DNA sequencing, Dartmouth scientists have identified potentially actionable mutations in cancers of the appendix. When specific mutations for a cancer type are identified, patients can be treated with chemotherapy or other targeted agents that work on those mutations.
Researchers Issue Update on Genetic-based Testing and Treatment for Breast Cancer
Dartmouth researchers at its Norris Cotton Cancer Center have compiled a review of the role that information gathered through genetic testing plays in the diagnosis and treatment of breast cancer.
Expert Insight: The limitations of personal genetics
Dartmouth Medicine asked geneticist Jason Moore about his thoughts on the FDA’s decision to order 23andMe, a company that provides personal genetic testing, to stop selling its genetic test for health-related purposes.
Dartmouth Research: Coevolution Between Humans and Bacteria Reduces Gastric Cancer Risk
Research carried out in two distinct communities in Colombia illustrates how coevolution between humans and bacteria can affect a person’s risk of disease.
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