Publications

(students in bold)

Fetalvero K.M., Shyu M, Nomikos AP, Wagner R.J., Powell R.J., Hwa J, Martin K.A. The prostacyclin receptor induces human vascular smooth muscle cell differentiation via the protein kinase A pathway Am J Physiol 290: H1337-H1346, 2006

Stitham J., Gleim S.R., Douville K., Arehart E., Hwa J. Versatility and differential roles of cysteine residues in human prostacyclin receptor structure and function. J Biol Chem 281(48):37227-36 2006

Stitham J., Arehart E.J., Gleim S.R., Douville K.L., Hwa J. Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations. Prostaglandins and Other Lipid Mediators 82,1:95-108 2007 (Review)

Fetalvero, K., Martin K.A., Hwa J. Cardioprotective prostacyclin signaling in vascular smooth muscle. Prostaglandins and Other Lipid Mediators 82,1:109-118 2007 (Review)

Arehart E, Gleim S, Kasza Z, Fetalvero K, Martin K.A., Hwa J. Prostacyclin atherothrombosis and cardiovascular disease.. Current Medicinal Chemistry 14(20): 2161-2169 2007 (Review)

Stitham J., Arehart E.J., Gleim S., Douville K.L., MacKenzie T., Hwa J. Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR). Gene 396(1):180-187 2007.

Stitham J, Arehart E.J., Gleim S.R., Li N., Douville K, Hwa J. New insights into human prostacyclin receptor function through natural and synthetic mutations of transmembrane charged residues. British Journal of Pharmacology (in Press) 2007

Martin KA, Merenick BL, Ding M, Fetalvero KM, Rzucidlo EM, Kozul CD, Brown DJ, Chiu HY, Shyu M, Drapeau BL, Wagner RJ, Powell RJ. Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate 1/phosphatidylinositol 3-kinase/Akt2 feedback signaling. J Biol Chem. 2007 Dec 7;282(49):36112-20.

Mabaera R, Greene MR, Richardson CA, Conine SJ, Kozul CD, Lowrey CH. Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin. Blood. 2008 Jan 1;111(1):411-20.

Farzan SF, Singh S, Schilling NS, Robbins DJ. Hedgehog Processing and Biological Activity. Am J Physiol Gastrointest Liver Physiol. 2008 Jan 31;

Arehart E, Stitham J, Asselbergs FW, Douville K, Mackenzie T, Fetalvero KM, Gleim S, Kasza Z, Rao Y, Martel L, Segel S, Robb J, Kaplan A, Simons M, Powell RJ, Moore JH, Rimm EB, Martin KA, Hwa J. Acceleration of Cardiovascular Disease by a Dysfunctional Prostacyclin Receptor Mutation. Potential Implications for Cyclooxygenase-2 Inhibition. Circ Res. 2008 Mar 6;

Freemantle SJ, Liu X, Feng Q, Galimberti F, Blumen S, Sekula D, Kitareewan S, Dragnev KH, Dmitrovsky E. Cyclin degradation for cancer therapy and chemoprevention. J Cell Biochem. 2007 Nov 1;102(4):869-77. (Review)

Farzan SF, Ascano M Jr, Ogden SK, Sanial M, Brigui A, Plessis A, Robbins DJ. Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway. Curr Biol. 2008 Aug 26;18(16):1215-20.

Kozul CD, Nomikos AP, Hampton TH, Warnke LA, Gosse JA, Davey JC, Thorpe JE, Jackson BP, Ihnat MA, Hamilton JW. Laboratory diet profoundly alters gene expression and confounds genomic analysis in mouse liver and lung. Chem Biol Interact. 2008 May 28;173(2):129-40.