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David J. Gladstone, Sc.D.

Title(s):
Associate Professor of Medicine
Chief of Clinical Physics

Department(s):
Medicine

Education:
Harvard Medical School, Post Doctoral Fellowship 1991
Massachusetts Institute of Technology Sc.D. 1989
University of Denver, B.S.Ch. 1983

Programs:
Norris Cotton Cancer Center

Contact Information:

Dartmouth Medical School
HB 7999
Hanover NH 03755

Office: 1 Medical Center Drive
Phone: 603-650-6442
Fax: 603-650-6616
Email: david.gladstone@dartmouth.edu


Professional Interests:

Ultra conformal radiation therapy to spare normal tissues from damage secondary to treatment. Image guided radiation therapy, biological gating of therapeutic X-ray beams, image guided brachytherapy.

Grant Information:

NIH/PO1 GM51630-05 Physics Consultant
NIH / NCI 1R43CA78005-01 - Phase II Co-Investigator
ACS grant #IRG82-003016IRG IRG-157M PI
NIH/NCI P01 CA23108-35 Co-director Radiation Shared Resource
NIH/NCI R43 CA103567-01 Co-Investigator

Courses Taught:

ENGS-56, ENGS-157


Selected Publications:

 

  • David J Gladstone, Michael F Flanagan, Jean B Southworth, Vaughn Hadley, MelissaWei Thibualt, Eugen B Hug and P Jack Hoopes Radiation-induced cardiomyopathy as a function of radiation beam gating to the cardiac cycle. Phys. Med. Biol. 49 (2004) 14751484

  • Hein P, Gladstone DJ, Bellerive MR, Hug EB Importance of protocol target definition on the ability to spare normal tissue: an IMRT and 3D-CRT planning comparison for intraorbital tumors. Int J. Radiat Oncol Biol Phys 2005 Aug 1;62(5) 1540-8

  • Lollis SS, Hug EB, Gladstone DJ, Chaffee S, Duhaime AC, Acquired Chiari malformation type I following fractionated radiation therapy to the anterior skull base in a 20-month-old boy. Case report. J Neurosurg. 2006 Feb;104(2 Suppl):133-7

  • Hou H, Lariviere JP, Demidenko E, Gladstone DJ, Swartz H, Kahn N Repeated tumor pO2 measurements by multi-site EPR oximetry as prognostic marker for enhanced therapeutic efficacy of fractionated radiotherapy. Submitted to Radiotherapy and Oncology 7/2008

  • Osterman KS, Hoopes PJ, Gladstone DJ, DeLorenzo C, Paulsen KD Non-invasive assessment of radiation injury with electrical impedance spectroscopy. Physics in Medicine and Biology,49(8):1475-84, 2004

  • Amdur RJ, Gladstone DJ, Leopold KA, Harris, RD Prostate seed implant quality assessment using MR and CT image fusion. Int. J. Radiation Oncology Biol. Phys., 1999;43(1):67-72