Margaret Rita Karagas, PhD
Chair and Professor of Epidemiology
Professor of Community and Family Medicine
Director, Children's Environmental Health and Disease Prevention Research Center and Center for Molecular Epidemiology
Community and Family Medicine
University of Washington, PhD 1990
Norris Cotton Cancer Center
Quantitative Biomedical Sciences
Department of Epidemiology
1 Medical Center Drive
7927 Rubin Building
Lebanon NH 03756
Office: 863 Rubin Bldg Lebanon, NH
Assistant: Claire Weaver
Asst. Phone: 603-653-9022
Asst. Email: Claire.Weaver@dartmouth.edu
Professor Karagas' research encompasses several epidemiological studies focusing on the etiology and prevention of human cancers, as well as adverse pregnancy and children's health outcomes. These include investigations to determine incidence rates of basal cell and squamous cell skin cancer for a geographically defined US population, and to assess the extent of any increase over the past 20 years. Another aspect of this research is a case-control study of these malignancies to identify risks associated with emerging exposures such as indoor tanning, ingestion of arsenic-containing drinking water and foods, immunosuppressive therapies and other factors. This research has been extended to bladder cancer. One of her current initiatives involves establishing a cohort of pregnant women in New Hampshire to assess the potential impact of arsenic and other exposures on risk of maternal and child health. Her ongoing work further includes studies of melanoma in women and collaborative investigations of exposure biomarkers, individual susceptibility, and biological response to environmental agents. Professor Karagas is one of the Principal Investigators of a NCI-funded cross-disciplinary postdoctoral training grant, serves as a mentor for early career investigators and participates in a variety of courses at the undergraduate and graduate level.
Bladder Cancer and Water Disinfection By-product Exposures through Multiple Routes: A Population-Based Case-Control Study (New England, USA).
Distinct arsenic metabolites following seaweed consumption in humans.
The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression.
Wood Stove Pollution in the Developed World: A Case to Raise Awareness Among Pediatricians.
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure and the associated health in later life.
Prenatal exposure to neurotoxic metals is associated with increased placental glucocorticoid receptor DNA methylation.
Levels of infants' urinary arsenic metabolites related to formula feeding and weaning with rice products exceeding the EU inorganic arsenic standard.
Maternal and infant inflammatory markers in relation to prenatal arsenic exposure in a U.S. pregnancy cohort.
Sexual epigenetic dimorphism in the human placenta: implications for susceptibility during the prenatal period.
Assessment of human dietary exposure to arsenic through rice.