Edit Entry

Margaret Rita Karagas, Ph.D.

Title(s):
Professor of Community and Family Medicine

Department(s):
Community and Family Medicine

Education:
University of Washington, PhD 1990

Programs:
Norris Cotton Cancer Center

Websites:
http://bio-epi.hitchcock.org

Contact Information:

Section of Biostatistics & Epidemiology, Dartmouth Medical School
1 Medical Center Drive
7927 Rubin Building
Lebanon NH 03756

Office: 863 Rubin Bldg Lebanon, NH
Phone: 603-653-9010
Fax: 603-653-9093
Email: Margaret.Karagas@dartmouth.edu

Assistant: Crystal Flaherty
Asst. Phone: 603-653-9022
Asst. Email: Crystal.M.Flaherty@Dartmouth.edu


Professional Interests:

Professor Karagas’ research includes several epidemiological studies focusing on the etiologic mechanisms and prevention of human cancers and other adverse health outcomes. Among these are investigations to determine the incidence rates of basal cell and squamous cell skin cancer and to assess the extent of any increase over the past 20 years. Another aspect of this research is a population-based case-control study of these malignancies designed to quantify the risks associated with emerging exposures such as tanning lamps, ingestion of arsenic-containing drinking water, immunosuppressive therapy and other factors. The research has been extended to study the effects of arsenic on bladder cancer and to conduct chemical analyses of household drinking water supplies. Her work also includes studies of melanoma among women and collaborative investigations of markers of individual susceptibility and biological response to environmental agents.

Grant Information:

http://bio-epi.hitchcock.org/research.html

Courses Taught:

http://bio-epi.hitchcock.org/education.html


Selected Publications:

 

  • Karagas MR, Nelson HH, Zens MS, Linet M, Stukel TA, Spencer S, Applebaum KM, Mott L, Mabuchi K. Squamous cell and basal cell carcinoma of the skin in relation to radiation therapy and potential modification of risk by sun exposure. Epidemiology 2007 Nov; 18(6): 776-84. (view details on MedLine)

  • Karagas MR, Stukel TA, Umland V, Tsoukas MM, Mott LA, Sorensen HT, Jensen AO, Nelson HH, Spencer SK, Perry AE, Stern RS. Reported use of photosensitizing medications and basal cell and squamous cell carcinoma of the skin: results of a population-based case-control study. J Invest Dermatol 2007 Dec; 127(12): 2901-3. (view details on MedLine)

  • Andrew AS, Karagas MR, Nelson HH, Guarrerra S, Polidoro S, Gamberini S, Sacerdote C, Moore JH, Kelsey KT, Demidenko E, Vineis P, Matullo G. DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy. Hum Hered 2008; 65(2): 105-18. (view details on MedLine)

  • Applebaum KM, Karagas MR, Hunter DJ, Catalano PJ, Byler SH, Morris S, Nelson HH. Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire. Environ Health Perspect 2007 Aug; 115(8): 1231-6. (view details on MedLine)

  • Karagas MR, Nelson HH, Sehr P, Waterboer T, Stukel TA, Andrew A, Green AC, Bavinck JN, Perry A, Spencer S, Rees JR, Mott LA, Pawlita M. Human papillomavirus infection and incidence of squamous cell and basal cell carcinomas of the skin. J Natl Cancer Inst 2006; 98(6): 389-95 (view details on MedLine)