Mardi A Crane-Godreau, Ph.D.
Assistant Professor of Microbiology and Immunology
Microbiology and Immunology
UVM 1968 BS
Massachusettes College of Liberal Arts 1998 BA
Dartmouth Medical School 2004 PhD
Norris Cotton Cancer Center
630 Rubin Bldg.
1 Medical Center Drive
Lebanon NH 03756
Mucosal immunology, effects of cigarette smoke exposure on innate immune function. Neuro-endocrine-immune system function and dysfunction.
Our lab has focused on the innate immune system at the mucosal surfaces. A special interest has been to determine the effects of cigarette smoke on changes in immune protection. The relationship of cigarette smoke exposure to increased risk of infection is well established, however the mechanisms involved are not. Our research shows that cigarette smoke exposure reduces production of a key antimicrobial chemokine, CCL20. New research in the lab seeks to determine the role of cigarette smoke exposure in neuro-endocrine-immune system dysregulation. This has implications in a range of disease states including infection, metabolic diseases, cancer and affective disorders such as depression and anxiety.
As director of the of the DMS CSEAL Dr Crane-Godreau manages the cigarette smoke exposure facility, supporting research in cancer biology, sudden infant death syndrome, cardiovascular, endocrine and immune system pathologies.
Research in our laboratory is supported by FAMRI, the Flight Attendant Medical Research Institute.
FAMRI (Flight Attendant Medical Research Institute)
Payne P, Crane-Godreau MA
Crane-Godreau MA, Black CC, Giustini AJ, Dechen T, Ryu J, Jukosky JA, Lee HK, Bessette K, Ratcliffe NR, Hoopes PJ, Fiering S, Kelly JA, Leiter JC
Robey RB, Crane-Godreau MA
Crane-Godreau MA, Payne P
Larsson L, Pehrson C, Dechen T, Crane-Godreau M
Crane-Godreau MA, Maccani MA, Eszterhas SK, Warner SL, Jukosky JA, Fiering S
Xia L, Crane-Godreau M, Leiter JC, Bartlett D Jr
Soboll G, Crane-Godreau MA, Lyimo MA, Wira CR
Crane-Godreau MA, Wira CR
Wira CR, Grant-Tschudy KS, Crane-Godreau MA