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Jason H. Moore, B.S., M.A., M.S., Ph.D.

Title(s):
Professor of Genetics
Professor of Community and Family Medicine
Third Century Professor
Director of the Institute for Quantitative Biomedical Sciences (iQBS)
Director of the Graduate Program in Quantitative Biomedical Sciences (QBS)
Associate Director, Norris-Cotton Cancer Center (NCCC)
Associate Director, SYNERGY
Editor-in-Chief, BioData Mining

Department(s):
Genetics
Community and Family Medicine

Education:
University of Michigan - PhD 1999 (Human Genetics)
University of Michigan - MA 1998 (Applied Statistics)
University of Michigan - MS 1994 (Human Genetics)
Florida State University - BS 1991 (Biological Sciences)

Programs:
Molecular and Cellular Biology Graduate Programs
Molecular Pathogenesis Program
Neuroscience Center at Dartmouth
Norris Cotton Cancer Center
Quantitative Biomedical Sciences
SYNERGY

Websites:
http://www.epistasis.org
http://www.iqbs.org
http://compgen.blogspot.com
http://www.twitter.com/moorejh

Contact Information:

DHMC
One Medical Center Dr.
HB 7937
Lebanon NH 03756

Office: 706 Rubin
Phone: 603-653-9939
Fax: 603-653-9952
Email: Jason.H.Moore@Dartmouth.edu

Assistant: Kim Becker
Asst. Phone: 603-653-3634
Asst. Email: Kimberly.S.Becker@Dartmouth.EDU


Professional Interests:

Artificial Intelligence, Artificial Life, Biodefense, Bioinformatics, Biomedical Informatics, Biostatistics, Canalization, Cancer, Cardiovascular Disease, Clinical Informatics, Complex Adaptive Systems, Computational Biology, Computational Genetics, Computational Intelligence, Data Mining, Digital Genetics, Environmental Health Sciences, Epidemiology, Epistasis, Evolutionary Computing, Functional Genomics, Gene-Environment Interaction, Genetic Architecture, Genetic Epidemiology, Genetic Heterogeneity, Genome-Wide Association Studies, Genomics, Human-Computer Interaction, Human Genetics, Information Visualization, Machine Learning, Metagenomics, Network Science, Neuropsychiatric Disease, Personal Genetics, Personalized Medicine, Pharmacogenetics, Pleiotropy, Reaction Norms, Software, Statistical Genetics, Systems Biology, Video Games, Visual Analytics

Rotations and Thesis Projects:

Rotation students are always welcome. Research projects range from applied analysis of complex biomedical data to theoretical aspects of computer science, complex adaptive systems and bioinformatics.

Grant Information:

NIH R01 AI59694 (PI - Moore) "Bioinformatics Strategies for Biodefense Vaccine Research"

NIH R01 LM009012 (PI - Moore) "Machine Learning Prediction of Cancer Susceptibility"

NIH R01 LM010098 (PI - Moore) "Bioinformatics Strategies for Genome-Wide Association Analysis"

NIH R01 EY022300 (PI - Moore) "Bioinformatics Approaches for Visual Disease Genetics"

NIH R01 LM011360 (PI - Moore) "Bioinformatics Strategies for Multidimensional Brain Imaging"

NIH P20 RR024475 (PI - Moore) "Quantitative Biology Research Institute"

NIH R25 CA134286 (PI - Moore) "Training Program for Quantitative Population Sciences"

NIH R41 GM097765 (PI - Moore) CG-GRID: Computational Genetics Grid Resource for Interaction Discovery

Courses Taught:

GEN/QBS 146: Molecular and Computational Genomics

Biography:

Dr. Moore was an Ingram Associate Professor of Cancer Research and a member of the Center for Human Genetics Research at Vanderbilt University before joining the faculty at The Geisel School of Medicine at Dartmouth in 2004. He was elected a Fellow of the American Association for the Advancement of Science (AAAS) in 2011. He was selected as a Kavli Fellow of the National Academy of Sciences in 2013. He serves as Editor-in-Chief of the journal BioData Mining.


Selected Publications:

 

Frost HR, Li Z, Moore JH
Spectral gene set enrichment (SGSE).
BMC Bioinformatics 2015 Mar 3; 16(1):70
PMID: 25879888

Yan J, Kim S, Nho K, Chen R, Risacher SL, Moore JH, Saykin AJ, Shen L
Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease.
Front Genet 2015; 6:117
PMID: 25859259

Hoen AG, Li J, Moulton LA, O'Toole GA, Housman ML, Koestler DC, Guill MF, Moore JH, Hibberd PL, Morrison HG, Sogin ML, Karagas MR, Madan JC
Associations between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis.
J Pediatr 2015 Mar 25;
PMID: 25818499

Beaulieu-Jones BR, O'Brien DM, Hopkins SE, Moore JH, Boyer BB, Gilbert-Diamond D
Sex, Adiposity, and Hypertension Status Modify the Inverse Effect of Marine Food Intake on Blood Pressure in Alaska Native (Yup'ik) People.
J Nutr 2015 May; 145(5):931-8
PMID: 25788581

Ma S, Johnson D, Ashby C, Xiong D, Cramer CL, Moore JH, Zhang S, Huang X
SPARCoC: a new framework for molecular pattern discovery and cancer gene identification.
PLoS One 2015; 10(3):e0117135
PMID: 25768286

White MJ, Eren F, Ağırbaşlı D, Chen J, Hu T, Moore JH, Williams SM, Ağırbaşlı M
A systems genetics approach to dyslipidemia in children and adolescents.
OMICS 2015 Apr; 19(4):248-59
PMID: 25671407

Huang X, Jennings SF, Bruce B, Buchan A, Cai L, Chen P, Cramer CL, Guan W, Hilgert UK, Jiang H, Li Z, McClure G, McMullen DF, Nanduri B, Perkins A, Rekepalli B, Salem S, Specker J, Walker K, Wunsch D, Xiong D, Zhang S, Zhang Y, Zhao Z, Moore JH
Big data - a 21st century science Maginot Line? No-boundary thinking: shifting from the big data paradigm.
BioData Min 2015; 8:7
PMID: 25670967

Pattin KA, Greene AC, Altman RB, Cohen KB, Wethington E, Gorg C, Hunter LE, Muse SV, Radivojac P, Moore JH
Training the next generation of quantitative biologists in the era of big data.
Pac Symp Biocomput 2015; :488-92
PMID: 25592609

Hu T, Darabos C, Cricco ME, Kong E, Moore JH
Genome-wide genetic interaction analysis of glaucoma using expert knowledge derived from human phenotype networks.
Pac Symp Biocomput 2015; :207-18
PMID: 25592582

Frost HR, Andrew AS, Karagas MR, Moore JH
A screening-testing approach for detecting gene-environment interactions using sequential penalized and unpenalized multiple logistic regression.
Pac Symp Biocomput 2015; :183-94
PMID: 25592580