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Brent L Berwin, Ph.D.

Title(s):
Associate Professor of Microbiology and Immunology

Department(s):
Microbiology and Immunology

Education:
University of Wisconsin-Madison, Ph.D., 1999
Lewis & Clark College, B.S., 1991

Dr. Berwin graduated from the University of Wisconsin-Madison in 1999. He did his postdoc training at Duke University and joined Dartmouth Medical School in the fall of 2004. Dr. Berwin is an Associate Professor in the Department of Microbiology and Immunology.

Programs:
Immunology Program
Molecular and Cellular Biology Graduate Programs
Norris Cotton Cancer Center

NIH Biosketch:
Berwin_B_BIO_2009-02-03.pdf

Websites:
http://dms.dartmouth.edu/microbio/
http://dms.dartmouth.edu/immuno/
http://www.dartmouth.edu/~immuno-cobre/

Contact Information:

Dartmouth Medical Center
1 Medical Center Dr.
HB 7556 - Rm. 614W
Lebanon NH 03756

Phone: 603-650-6899
Fax: 603-650-6223
Email: berwin@dartmouth.edu

Selected Publications:
 

Patankar YR, Lovewell RR, Poynter ME, Jyot J, Kazmierczak BI, Berwin B
Flagellar Motility Is a Key Determinant of the Magnitude of the Inflammasome Response to Pseudomonas aeruginosa.
Infect Immun 2013 Jun; 81(6):2043-52
PMID: 23529619

Lovewell RR, Collins RM, Acker JL, O'Toole GA, Wargo MJ, Berwin B
Step-wise loss of bacterial flagellar torsion confers progressive phagocytic evasion.
PLoS Pathog 2011 Sep; 7(9):e1002253
PMID: 21949654

Hart KM, Byrne KT, Molloy MJ, Usherwood EM, Berwin B
IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer.
Front Immunol 2011; 2:29
PMID: 22566819

Amiel E, Lovewell RR, O'Toole GA, Hogan DA, Berwin B
Pseudomonas aeruginosa evasion of phagocytosis is mediated by loss of swimming motility and is independent of flagellum expression.
Infect Immun 2010 Jul; 78(7):2937-45
PMID: 20457788

Peter S, Bak G, Hart K, Berwin B
Ovarian tumor-induced T cell suppression is alleviated by vascular leukocyte depletion.
Transl Oncol 2009 Dec; 2(4):291-9
PMID: 19956391

Amiel E, Acker JL, Collins RM, Berwin B
Uncoupling scavenger receptor A-mediated phagocytosis of bacteria from endotoxic shock resistance.
Infect Immun 2009 Oct; 77(10):4567-73
PMID: 19667044

Hart KM, Bak SP, Alonso A, Berwin B
Phenotypic and functional delineation of murine CX(3)CR1 monocyte-derived cells in ovarian cancer.
Neoplasia 2009 Jun; 11(6):564-73, 1 p following 573
PMID: 19484145

Amiel E, Alonso A, Uematsu S, Akira S, Poynter ME, Berwin B
Pivotal Advance: Toll-like receptor regulation of scavenger receptor-A-mediated phagocytosis.
J Leukoc Biol 2009 Apr; 85(4):595-605
PMID: 19112093

Bak SP, Alonso A, Turk MJ, Berwin B
Murine ovarian cancer vascular leukocytes require arginase-1 activity for T cell suppression.
Mol Immunol 2008 Dec; 46(2):258-68
PMID: 18824264

Bak SP, Amiel E, Walters JJ, Berwin B
Calreticulin requires an ancillary adjuvant for the induction of efficient cytotoxic T cell responses.
Mol Immunol 2008 Mar; 45(5):1414-23
PMID: 17936359