Donald Bartlett, M.D.
Title(s):
Professor of Physiology and Neurobiology
Department(s):
Physiology and Neurobiology
Education:
Dartmouth College, AB 1959
Dartmouth Medical School, BMS 1961
Harvard Medical School, MD 1964
Programs:
Program in Experimental and Molecular Medicine
Websites:
http:
Contact Information:
Room 736E
Borwell Building
Dartmouth Medical School
Lebanon NH 03756
Office: 736E Borwell
Phone: 603-650-7723
Fax: 603-650-6130
Email: donald.bartlett@dartmouth.edu
Professional Interests:
Dr. Bartlett's research is directed at elucidating the role of the upper airways in the control of breathing. Studies focus both on the sensory physiology of the larynx and on the control of muscles that influence resistance to airflow through the nose, pharynx, larynx and trachea. The work is intended to advance the understanding of normal upper airway physiology and to provide information that will aid in the diagnosis and management of diseases, such as obstructive sleep apnea and the sudden infant death syndrome. Current experiments are focused on laryngeal chemoreflex apnea, its enhancement by hyperthermia and its possible role in the pathogenesis of the Sudden Infant Death Syndrome.
Rotations and Thesis Projects:
None available at present
Grant Information:
Supported by grants from the National Institute of Child Health and Human Development
Courses Taught:
Physiology 110 (Course Director)
Physiology 125
Scientific Basis of Medicine
PEMM 101 - Scientific Basis of Disease
Biography:
After graduating from Dartmouth College in 1959 with a B.A. in English, Dr. Bartlett attended medical school at Dartmouth and Harvard, receiving his M.D. in 1964. He studied physiology at Dartmouth as a predoctoral fellow in 1961-62. Following internship and residency training in internal medicine at Strong Memorial Hospital in Rochester, New York, he joined the U.S. Public Health Service, serving first as an air pollution epidemiologist and then as Chief of the Medical Research Section of the Health Effects Research Program at the National Center for Air Pollution Control. In 1968 he returned to Dartmouth as a postdoctoral fellow in Physiology and joined the faculty in 1971. He has been Professor of Physiology since 1978 and was Andrew C. Vail Professor (1989 – 2010). He served as Department Chairman for 17 years (1989–2005).
Selected Publications: |
|
Curran AK, Xia L, Leiter JC, Bartlett D Jr. Elevated body temperature enhances the laryngeal chemoreflex in decerebrate piglets. J Appl Physiol. 2005 Mar;98(3):780-6. Epub 2004 Nov 12. (view details on MedLine) Xia L, Leiter JC, Bartlett D Jr. Laryngeal water receptors are insensitive to body temperature in neonatal piglets. Respir Physiol Neurobiol. 2006 Jan 25;150(1):82-6. Epub 2005 Jul 1. (view details on MedLine) Xia L, Damon TA, Leiter JC, Bartlett D Jr. Focal warming in the nucleus of the solitary tract prolongs the laryngeal chemoreflex in decerebrate piglets. J Appl Physiol. 2007 Jan;102(1):54-62. Epub 2006 Sep 7. (view details on MedLine) Böhm I., Xia L, Leiter JC, Bartlett D Jr. GABAergic processes mediate thermal prolongation of the laryngeal reflex apnea in decerebrate piglets. Respir. Physiol. & Neurobiol. 156:229-233, 2007. Xia L, Damon T, Niblock MM, Bartlett D Jr, Leiter JC. Unilateral microdialysis of gabazine in the dorsal medulla reverses thermal prolongation of the laryngeal chemoreflex in decerebrate piglets. J Appl Physiol. 2007 Nov;103(5):1864-72. Epub 2007 Sep 6. (view details on MedLine) Xia L, Leiter JC, Bartlett D Jr. Laryngeal apnea in rat pups: effects of age and body temperature. J Appl Physiol. 2008 Jan;104(1):269-74. Epub 2007 Oct 25. (view details on MedLine) Xia L, Bartlett D Jr, Leiter JC. An adenosine A(2A) antagonist injected in the NTS reverses thermal prolongation of the LCR in decerebrate piglets. Respir Physiol Neurobiol. 2008 Dec 31;164(3):358-65. Epub 2008 Aug 15. (view details on MedLine) Xia L, Crane-Godreau M, Leiter JC, Bartlett D Jr. Gestational cigarette smoke exposure and hyperthermic enhancement of laryngeal chemoreflex in rat pups. Respir Physiol Neurobiol. 2009 Feb 28;165(2-3):161-6. Epub 2008 Nov 12. (view details on MedLine) Xia L, Leiter JC, Bartlett D Jr. Gestational nicotine exposure exaggerates hyperthermic enhancement of laryngeal chemoreflex in rat pups. Respir Physiol Neurobiol. 2010 Apr 15;171(1):17-21. Epub 2010 Jan 25. (view details on MedLine) Duy PM, Xia L, Bartlett D Jr, Leiter JC. An adenosine A(2A) agonist injected in the nucleus of the solitary tract prolongs the laryngeal chemoreflex by a GABAergic mechanism in decerebrate piglets. Exp Physiol. 2010 Jul;95(7):774-87. Epub 2010 Apr 23. (view details on MedLine) |
|