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Rahul Sarpeshkar, PhD

Professor of Microbiology and Immunology
Professor of Physiology and Neurobiology

Additional Titles/Positions/Affiliations:
Thomas E. Kurtz Professor
Professor of Engineering
Professor of Physics

Microbiology and Immunology
Physiology and Neurobiology

BS, Electrical Engineering and Physics, MIT
PhD, Computation and Neural Systems, California Institute of Technology

Molecular and Cellular Biology Graduate Programs


Contact Information:

Professional Interests:

Synthetic analog and digital biological circuits in electri-cigenic and other microbes. Applications of synthetic and systems biology to immunology, infectious disease, and cancer.


ONR Young Investigator Award
Packard Fellow Award
Junior Bose Teaching Award, MIT

Selected Publications:


Bioelectronic measurement and feedback control of molecules in living cells.
Banerjee A, Weaver I, Thorsen T, Sarpeshkar R
Sci Rep. 2017 Oct 2;7(1):12511. doi: 10.1038/s41598-017-12655-2. Epub 2017 Oct 2.
PMID: 28970494

Guest Editorial - Special Issue on Synthetic Biology.
Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2015 Aug;9(4):449-52.
PMID: 26839930

Synthetic Biology: A Unifying View and Review Using Analog Circuits.
Teo JJ, Woo SS, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2015 Aug;9(4):453-74. Epub 2015 Sep 11.
PMID: 26372648

Analog synthetic biology.
Sarpeshkar R
Philos Trans A Math Phys Eng Sci. 2014 Mar 28;372(2012):20130110. doi: 10.1098/rsta.2013.0110. Epub 2014 Feb 24.
PMID: 24567476

Synthetic analog computation in living cells.
Daniel R, Rubens JR, Sarpeshkar R, Lu TK
Nature. 2013 May 30;497(7451):619-23. doi: 10.1038/nature12148. Epub 2013 May 15.
PMID: 23676681

Efficient universal computing architectures for decoding neural activity.
Rapoport BI, Turicchia L, Wattanapanitch W, Davidson TJ, Sarpeshkar R
PLoS One. 2012;7(9):e42492. doi: 10.1371/journal.pone.0042492. Epub 2012 Sep 12.
PMID: 22984404

A glucose fuel cell for implantable brain-machine interfaces.
Rapoport BI, Kedzierski JT, Sarpeshkar R
PLoS One. 2012;7(6):e38436. doi: 10.1371/journal.pone.0038436. Epub 2012 Jun 12.
PMID: 22719888

An energy-efficient, adiabatic electrode stimulator with inductive energy recycling and feedback current regulation.
Arfin SK, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2012 Feb;6(1):1-14. doi: 10.1109/TBCAS.2011.2166072.
PMID: 23852740

A low-power 32-channel digitally programmable neural recording integrated circuit.
Wattanapanitch W, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2011 Dec;5(6):592-602. doi: 10.1109/TBCAS.2011.2163404.
PMID: 23852555

An articulatory silicon vocal tract for speech and hearing prostheses.
Keng Hoong Wee, Turicchia L, Sarpeshkar R
IEEE Trans Biomed Circuits Syst. 2011 Aug;5(4):339-46. doi: 10.1109/TBCAS.2011.2159858.
PMID: 23851948