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James B Moseley, PHD

Associate Professor of Biochemistry and Cell Biology

Biochemistry and Cell Biology

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Selected Publications:


Cell size-dependent regulation of Wee1 localization by Cdr2 cortical nodes.
Allard CAH, Opalko HE, Liu KW, Medoh U, Moseley JB
J Cell Biol. 2018 Mar 7; pii: jcb.201709171. doi: 10.1083/jcb.201709171. Epub 2018 Mar 7.
PMID: 29514920

Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division.
Lee ME, Rusin SF, Jenkins N, Kettenbach AN, Moseley JB
Curr Biol. 2018 Jan 8;28(1):84-92.e4. doi: 10.1016/j.cub.2017.11.034. Epub 2017 Dec 14.
PMID: 29249658

Dynamic regulation of Cdr1 kinase localization and phosphorylation during osmotic stress.
Opalko HE, Moseley JB
J Biol Chem. 2017 Nov 10;292(45):18457-18468. doi: 10.1074/jbc.M117.793034. Epub 2017 Sep 18.
PMID: 28924043

Transient activation of fission yeast AMPK is required for cell proliferation during osmotic stress.
Schutt KL, Moseley JB
Mol Biol Cell. 2017 Jul 1;28(13):1804-1814. doi: 10.1091/mbc.E17-04-0235. Epub 2017 May 17.
PMID: 28515144

Wee1 and Cdc25: Tools, pathways, mechanisms, questions.
Moseley JB
Cell Cycle. 2017 Apr 3;16(7):599-600. doi: 10.1080/15384101.2017.1302229.
PMID: 28272970

Phosphatases Generate Signal Specificity Downstream of Ssp1 Kinase in Fission Yeast.
Deng L, Lee ME, Schutt KL, Moseley JB
Mol Cell Biol. 2017 May 15;37(10) pii: e00494-16. doi: 10.1128/MCB.00494-16. Epub 2017 May 2.
PMID: 28223368

CAG Expansions Are Genetically Stable and Form Nontoxic Aggregates in Cells Lacking Endogenous Polyglutamine Proteins.
Zurawel AA, Kabeche R, DiGregorio SE, Deng L, Menon KM, Opalko H, Duennwald ML, Moseley JB, Supattapone S
MBio. 2016 Sep 27;7(5) pii: e01367-16. doi: 10.1128/mBio.01367-16. Epub 2016 Sep 27.
PMID: 27677791

Pil1 cytoplasmic rods contain bundles of crosslinked tubules.
Kabeche R, Howard L, Moseley JB
Commun Integr Biol. 2015 Jan-Feb;8(1):e990848. doi: 10.4161/19420889.2014.990848. Epub 2015 Mar 4.
PMID: 26609339

Eisosomes provide membrane reservoirs for rapid expansion of the yeast plasma membrane.
Kabeche R, Howard L, Moseley JB
J Cell Sci. 2015 Nov 15;128(22):4057-62. doi: 10.1242/jcs.176867. Epub 2015 Sep 24.
PMID: 26403204

Eisosomes Regulate Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2) Cortical Clusters and Mitogen-activated Protein (MAP) Kinase Signaling upon Osmotic Stress.
Kabeche R, Madrid M, Cansado J, Moseley JB
J Biol Chem. 2015 Oct 23;290(43):25960-73. doi: 10.1074/jbc.M115.674192. Epub 2015 Sep 10.
PMID: 26359496