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Jeremiah R. Brown

Title(s):
Associate Professor of The Dartmouth Institute
Associate Professor of Epidemiology
Associate Professor of Biomedical Data Science

Department(s):
The Dartmouth Institute
Epidemiology
Biomedical Data Science

Education:
BS - 1999 St. Lawrence University
MS - 2003 Dartmouth College, CECS Program
PhD - 2006 Dartmouth College, CECS Program

Programs:
Heart and Vascular Research Center
SYNERGY
The Dartmouth Institute for Health Policy and Clinical Practice

Websites:
www.nnecdsg.org

Contact Information:

Dartmouth-Hitchcock Medical Center
HB 7505
Lebanon NH 03756

Office: Rubin
Phone: (603) 653-3576
Fax: (603) 653-3554
Email: Jeremiah.R.Brown@Dartmouth.edu

Assistant: Suzanne Burge
Asst. Phone: (603) 653-0824
Asst. Email: Suzanne.L.Burge@Dartmouth


Professional Interests:

Cardiovascular Epidemiology and Health Services Research
Risk prediction and risk modeling
Contrast-induced Acute Kidney Injury
Cardiac Surgery Associated Acute Kidney Injury
Molecular Epidemiology and Biomarkers for risk prediction

Grant Information:

National Heart, Lung and Blood Institute (NHLBI), Novel Biomarkers to Predict Readmission in Pediatric and Adult Heart Surgery R01 HL119664

National Heart, Lung and Blood Institute (NHLBI), Information Extraction from EMRs to Predict Readmission following Acute Myocardial Infarction R01 HL130828

Health Services Research and Development Service (HSR&D), National Surveillance of Acute Kidney Injury Following Cardiac Catheterization


Courses Taught:

Research Capstone, The Dartmouth Institute for Health Policy and Clinical Practice (ECS 177, 178, 179)
PH 117, Co-Director, Health and Healthcare Improvement
PH 126, Co-Director Statistical Methods for Healthcare Improvement
PH233, Co-Director, Statistics for Improvement
SYNERGY Certificate Program

Biography:

Dr. Brown is the principal investigator on two NHLBI R01 grants focusing on predictive analytics for readmission. He leads the Cardiovascular Outcomes team at The Dartmouth Institute focusing on cardiovascular epidemiology and biomedical informatics research. Dr. Brown has also received funding from the American Heart Association focusing on molecular epidemiology, Agency for Healthcare Research and Quality (AHRQ) studying patient safety and acute kidney injury, and the Veterans Administration focusing on the development and evaluation of a national risk model for acute kidney injury.

An active collaborator on a global scale, Dr. Brown develops guidelines for the Acute Kidney Injury Network, is a guidelines taskforce member for the International Consortium of Evidence Based Perfusion, and is a taskforce member for the Workforce on Cardiopulmonary Bypass for the Society for Thoracic Surgeons (STS) where he leads the Renal workgroup. He is a member of the American Heart Association (AHA), the Society of Thoracic Surgeons (STS), American Medical Informatics Association (AMIA), and the Northern New England Cardiovascular Disease Study Group (NNE).

An associate professor of epidemiology, and associate professor of biomedical data science at the Geisel School of Medicine, Dr. Brown is committed to supporting student research and instruction. Dr. Brown and the Cardiovascular Outcomes team is currently training PhD students, postdoctoral fellows, clilnical residents and fellows, TDI graduate students, medical school fellows, and undergraduate scholars through the Women in Science (WISP) program, Neukom Institute, and undergraduate advising & research (UGAR).

The author of more than 110 publications, Brown has published in the New England Journal of Medicine, Journal of the American Medical Association, British Medical Journal Quality and Safety, Circulation, and many others. He serves as epidemiology and statistics editor for the Journal of ExtraCorporeal Technology and a referee for more than a dozen additional medical journals. He earned a BS from St. Lawrence University and a MS and PhD from The Dartmouth Institute for Health Policy and Clinical Practice.


Selected Publications:

 

  • Brown JR, Sox HC, Goodman DC Financial incentives to improve quality: skating to the puck or avoiding the penalty box? JAMA. 2014 Mar 12;311(10):1009-10. (view details on MedLine)

  • Brown JR, O'Connor GT Coronary heart disease and prevention in the United States. N Engl J Med. 2010 Jun 10;362(23):2150-3 (view details on MedLine)

  • Brown JR, MacKenzie TA, Dacey LJ, Leavitt BJ, Braxton JH, Westbrook BM, Helm RE, Klemperer JD, Frumiento C, Sardella GL, Ross CS, O'Connor GT Using biomarkers to improve the preoperative prediction of death in coronary artery bypass graft patients. J Extra Corpor Technol. 2010 Dec;42(4):293-300. (view details on MedLine)

  • Brown JR, Robb JF, Block CA, Schoolwerth AC, Kaplan AV, O'Connor GT, Solomon RJ, Malenka DJ. Does safe dosing of iodinated contrast prevent contrast-induced acute kidney injury? Circ Cardiovasc Interv. 2010 Aug;3(4):346-50. Epub 2010 Jun 29. (view details on MedLine)

  • Brown JR, Block CA, Malenka DJ, O'Connor GT, Schoolwerth AC, Thompson CA. Sodium bicarbonate plus N-acetylcysteine prophylaxis: a meta-analysis. JACC Cardiovasc Interv. 2009 Nov;2(11):1116-24. Review. (view details on MedLine)

  • Brown JR, Malenka DJ, DeVries JT, Robb JF, Jayne JE, Friedman BJ, Hettleman BD, Niles NW, Kaplan AV, Schoolwerth AC, Thompson CA; Dartmouth Dynamic Registry Investigators. Transient and persistent renal dysfunction are predictors of survival after percutaneous coronary intervention: insights from the Dartmouth Dynamic Registry. Catheter Cardiovasc Interv. 2008 Sep 1;72(3):347-54. (view details on MedLine)

  • Brown JR, Cochran RP, Leavitt BJ, Dacey LJ, Ross CS, MacKenzie TA, Kunzelman KS, Kramer RS, Hernandez F Jr, Helm RE, Westbrook BM, Dunton RF, Malenka DJ, O'Connor GT; Northern New England Cardiovascular Disease Study Group. Multivariable prediction of renal insufficiency developing after cardiac surgery. Circulation. 2007 Sep 11;116(11 Suppl):I139-43. (view details on MedLine)

  • Brown JR, DeVries JT, Piper WD, Robb JF, Hearne MJ, Ver Lee PM, Kellet MA, Watkins MW, Ryan TJ, Silver MT, Ross CS, MacKenzie TA, O'Connor GT, Malenka DJ; Northern New England Cardiovascular Disease Study Group. Serious renal dysfunction after percutaneous coronary interventions can be predicted. Am Heart J. 2008 Feb;155(2):260-6. Epub 2007 Nov 26. (view details on MedLine)

  • Brown JR, Cochran RP, Dacey LJ, Ross CS, Kunzelman KS, Dunton RF, Braxton JH, Charlesworth DC, Clough RA, Helm RE, Leavitt BJ, Mackenzie TA, O'Connor GT; Northern New England Cardiovascular Disease Study Group. Perioperative increases in serum creatinine are predictive of increased 90-day mortality after coronary artery bypass graft surgery. Circulation. 2006 Jul 4;114(1 Suppl):I409-13. (view details on MedLine)

  • Brown JR, O'Connor GT. Coronary heart disease and prevention in the United States. N Engl J Med. 2010 Jun 10;362(23):2150-3. (view details on MedLine)